3.4.21.75: Furin

This is an abbreviated version!
For detailed information about Furin, go to the full flat file.

Word Map on EC 3.4.21.75

Reaction

Release of mature proteins from their proproteins by cleavage of -Arg-Xaa-Yaa-Arg-/- bonds, where Xaa can by any amino acid and Yaa is Arg or Lys. Releases albumin, complement component C3 and von Willebrand factor from their respective precursors =

Synonyms

More, Proprotein convertase, prohormone convertase, Dibasic processing enzyme, PACE, Paired basic amino acid cleaving enzyme, Paired basic amino acid converting enzyme, Serine proteinase PACE, PC1, SPC3, PC2, Paired basic amino acid residue cleaving enzyme, Trans golgi network protease furin, sheddase, Bfurin, Sfurin, hfurin, PC1/3, prohormone convertase 1, prohormone convertase 2, furin convertase, proconvertase, subtilisin-like proprotein convertase, furin-like protease, subtilisin-like protein convertase, furin protease, furin B, furin A, furin, PCSK3, proprotein convertase subtilisin/kexin type 3, furin-like prohormone convertase, furin-like proprotein convertase, FurinA, furinase, proprotein convertase subtilisin/kexin type3, FUR, Dfurin1, KPC-1, proprotein convertase subtilisin/kexin 3, furin-like proteinase, furin-like pro-protein convertase

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.75 Furin