3.4.21.74: venombin A

This is an abbreviated version!
For detailed information about venombin A, go to the full flat file.

Word Map on EC 3.4.21.74

Reaction

Selective cleavage of Arg-/- bond in fibrinogen, to form fibrin, and release fibrinopeptide A. The specificity of further degradation of fibrinogen varies with species origin of the enzyme =

Synonyms

alpha-Fibrinogenase, Habutobin, Ancrod, Batroxobin, Crotalase, EC 3.4.21.28, EC 3.4.21.29, EC 3.4.21.30, TLE, Bothrops atrox serine proteinase, Protein C activator, Reptilase, Thrombin-like enzyme, bothrombin, VLAF, viper venom serine protease, albofibrase1, alpha fibrinogenase, RVBCMP, Russell's viper basic coagulant metalloprotease, venom gloshedobin, gloshedobin, Bhalternin, TA-2, thrombin-like serine protease, BpirSP-39, RVV protease, VaF1, beta-fibrinogenase, VLBF, metalloproteinase 1, Vaa serine proteinase homolog 1, VaaSPH-1, snake venom serine protease, Lachesis stenophrys venom serine proteinase, Dav-PA, AaV-SP-II, coagulant serine protease, VLCII

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.74 venombin A

KM Value

KM Value on EC 3.4.21.74 - venombin A

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.39
benzoyl-Pro-Phe-Arg 4-nitroanilide
-
-
0.025
carbobenzoxyl-Glu-(alpha-tert-butoxy)-Gly-Arg-4-nitroanilide
-
-
0.18
D-Phe-L-pipecoyl-L-Arg 4-nitroanilide
0.06
D-Pro-L-Phe-L-Arg 4-nitroanilide
-
-
0.14
D-Val-L-Leu-L-Arg 4-nitroanilide
-
-
3.3
H-D-Aminobutyric acid-cyclohexylalanyl-Lys 4-nitroanilide
-
methylsulfonyl-Leu-Gly-Arg 4-nitroanilide
0.45
H-D-Hexahydrotyrosyl-Ala-Arg 4-nitroanilide
-
-
0.27
H-D-Nle-cyclohexylalanyl-Arg 4-nitroanilide
-
H-D-phenylglycyl-Phe-Arg 4-nitroanilide
2.7
H-D-Nle-hexahydrotyrosyl-Lys 4-nitroanilide
-
-
0.058
H-D-Pro-hexahydrotyrosyl-Arg 4-nitroanilide
-
-
0.0066 - 0.0105
human plasma fibrinogen
-
0.3
Tosyl-Gly-Pro-Arg 4-nitroanilide
-
-
1.4
tosyl-Gly-Pro-Lys 4-nitroanilide
-
-