3.4.21.69: Protein C (activated)

This is an abbreviated version!
For detailed information about Protein C (activated), go to the full flat file.

Word Map on EC 3.4.21.69

Reaction

degradation of blood coagulation factors Va and VIIIa =

Synonyms

Blood-coagulation factor XIVa, Activated blood coagulation factor XIV, Activated protein C, Autoprothrombin II-A, Blood-coagulation factor XIV, activated, Protein Ca, APC, GSAPC, Autoprothrombin IIA, Blood coagulation factor XIV, anticoagulant protein C/protein S system, rhAPC, anticoagulant activated protein C, hAPC, ghrelin endopeptidase, anticoagulant serine protease-activated protein C, anticoagulant-activated protein C, PROC

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.69 Protein C (activated)

Purification

Purification on EC 3.4.21.69 - Protein C (activated)

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PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
mutant
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native enzyme from bovine plasma by gel filtration, mannose affinity and Blue Sepharose chromatography
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recombinant enzyme
recombinant wild-type and mutant enzymes from HEK-293 cell culture medium by anion exchange chromatography
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use of the insolubilized inhibitor aprotinin for purification
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