3.4.21.67: Endopeptidase So

This is an abbreviated version!
For detailed information about Endopeptidase So, go to the full flat file.

Word Map on EC 3.4.21.67

Reaction

Hydrolysis of proteins, but not Bz-Tyr-OEt, Ac-Phe-beta-naphthylester, or Bz-Arg-Oet =

Synonyms

EC 3.4.21.14, E. coli cytoplasmic proteinase, Proteinase So, Escherichia coli serine proteinase So, Proteinase, Escherichia coli serine, So, endopeptidase So, SK-1, subtilisin kexin isozyme-1, kexin

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.67 Endopeptidase So

Substrates Products

Substrates Products on EC 3.4.21.67 - Endopeptidase So

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
Abz-DIYISRRLL-GTFT-Tyx-A + H2O
Abz-DIYISRRLL + GTFT-Tyx-A
show the reaction diagram
-
-
-
-
?
Ac-Ala4 + H2O
?
show the reaction diagram
-
-
-
-
?
Acid-soluble peptides + H2O
?
show the reaction diagram
-
-
-
-
?
Ada protein + H2O
19000 MW polypeptide + 18000 MW fragment
show the reaction diagram
-
a DNA repair enzyme and a transcriptional activator of the expression of its own ada gene, generation of a C-terminal 19000 MW polypeptide and further processing mainly to an 18000 MW fragment
-
?
Ada protein + H2O
?
show the reaction diagram
-
involved in endogenous cleavage of Ada protein (a DNA repair enzyme and a transcriptional activator of the expression of its own ada gene), which may play a role in down-regulating the adaptive response to alkylating agents
-
-
?
casein + H2O
?
show the reaction diagram
-
-
-
-
?
casein + H2O
hydrolyzed casein
show the reaction diagram
-
-
-
-
?
Denatured bovine serum albumin + H2O
Hydrolyzed denatured bovine serum albumin
show the reaction diagram
-
-
-
?
denatured bovine serum albumine + H2O
?
show the reaction diagram
-
-
-
-
?
Globin + H2O
?
show the reaction diagram
-
-
-
-
?
Globin + H2O
Hydrolyzed globin
show the reaction diagram
-
-
-
-
?
Glucagon + H2O
?
show the reaction diagram
-
-
-
-
?
Glucagon + H2O
Hydrolyzed glucagon
show the reaction diagram
-
-
-
?
Methyl-alpha-casein + H2O
Hydrolyzed methyl-alpha-casein
show the reaction diagram
-
-
-
?
Methylhemoglobin + H2O
Hydrolyzed methylhemoglobin
show the reaction diagram
-
-
-
?
Oxidatively damaged glutamine synthetase + H2O
?
show the reaction diagram
-
to acid-soluble peptides, degradation is 5-10times faster than with the native glutamine synthetase
-
-
?
additional information
?
-