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3.4.21.57: Leucyl endopeptidase

This is an abbreviated version!
For detailed information about Leucyl endopeptidase, go to the full flat file.

Word Map on EC 3.4.21.57

Reaction

Hydrolysis of proteins. Preferential cleavage: Leu-/- in small molecule substrates =

Synonyms

Leu-proteinase, Leucine endopeptidase, Leucine-specific serine proteinase, Plant Leu-proteinase, Proteinase, leucine-specific, Proteinase, spinach serine (leucine specific), Spinach leucine-specific serine proteinase

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.57 Leucyl endopeptidase

Inhibitors

Inhibitors on EC 3.4.21.57 - Leucyl endopeptidase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1,10-phenanthroline
-
20% inhibition at 0.01 mM, 55% inhibition at 0.1 mM, 64% inhibition at 0.5 mM
bestatin
-
6% inhibition at 0.001 mM, 39% inhibition at 0.005 mM, 54% inhibition at 0.01 mM, 57% inhibition at 0.1 mM
Cu2+
-
87% inhibition at 1 mM
diisopropyl fluorophosphate
-
-
EDTA
-
45% inhibition at 0.01 mM, 64% inhibition at 0.1 mM, 84% inhibition at 0.5 mM
Eglin c
-
-
EGTA
-
17% inhibition at 0.01 mM, 44% inhibition at 0.1 mM, 44% inhibition at 0.5 mM
Fe2+
-
100% inhibition at 0.1 mM
Nalpha-tosyl-L-Leu chloromethyl ketone
-
-
phenylmethylsulfonyl fluoride
Soybean Bowman-Birk proteinase inhibitor
-
and its chymotrypsin and trypsin inhibiting fragments
-