3.4.21.57: Leucyl endopeptidase
This is an abbreviated version!
For detailed information about Leucyl endopeptidase, go to the full flat file.
Word Map on EC 3.4.21.57
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3.4.21.57
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mast
-
histamine
-
allergic
-
degranulation
-
chymase
-
anaphylaxis
-
basophil
-
mastocytosis
-
eosinophil
-
asthma
-
nafamostat
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tryptase-induced
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anti-tryptase
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beta-tryptase
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leech-derived
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tryptase-positive
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anaphylactic
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ige-dependent
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proteinase-activated
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trypsin-like
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chymase-positive
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mast-cell
-
receptor-2
-
mesilate
-
anti-ige
- 3.4.21.57
-
mast
- histamine
-
allergic
-
degranulation
- chymase
-
anaphylaxis
-
basophil
-
mastocytosis
-
eosinophil
-
asthma
- nafamostat
-
tryptase-induced
-
anti-tryptase
-
beta-tryptase
-
leech-derived
-
tryptase-positive
-
anaphylactic
-
ige-dependent
-
proteinase-activated
-
trypsin-like
-
chymase-positive
-
mast-cell
-
receptor-2
- mesilate
-
anti-ige
Reaction
Hydrolysis of proteins. Preferential cleavage: Leu-/- in small molecule substrates =
Synonyms
Leu-proteinase, Leucine endopeptidase, Leucine-specific serine proteinase, Plant Leu-proteinase, Proteinase, leucine-specific, Proteinase, spinach serine (leucine specific), Spinach leucine-specific serine proteinase
ECTree
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Inhibitors
Inhibitors on EC 3.4.21.57 - Leucyl endopeptidase
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1,10-phenanthroline
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20% inhibition at 0.01 mM, 55% inhibition at 0.1 mM, 64% inhibition at 0.5 mM
bestatin
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6% inhibition at 0.001 mM, 39% inhibition at 0.005 mM, 54% inhibition at 0.01 mM, 57% inhibition at 0.1 mM
EDTA
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45% inhibition at 0.01 mM, 64% inhibition at 0.1 mM, 84% inhibition at 0.5 mM
EGTA
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17% inhibition at 0.01 mM, 44% inhibition at 0.1 mM, 44% inhibition at 0.5 mM
Soybean Bowman-Birk proteinase inhibitor
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and its chymotrypsin and trypsin inhibiting fragments
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67% inhibition at 0.01 mM, 100% inhibition above 0.1 mM