3.4.21.54: gamma-Renin

This is an abbreviated version!
For detailed information about gamma-Renin, go to the full flat file.

Word Map on EC 3.4.21.54

Reaction

Cleavage of the Leu-/-Leu bond in synthetic tetradecapeptide renin substrate (horse), to produce angiotensin I, but not active on natural angiotensinogen, unlike renin (EC 3.4.23.15). Also hydrolyses Bz-Arg-p-nitroanilide =

Synonyms

renin, gamma-, MGK-16, kallikrein 16, mK 16, S01.163

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.54 gamma-Renin

Natural Substrates Products

Natural Substrates Products on EC 3.4.21.54 - gamma-Renin

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
additional information
?
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it is proposed that gamma-renin in mouse saliva cleaves peptides which are homologous to angiotensinogen and have potent vasoactivity and action in the central nervous system
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?