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3.4.21.53: Endopeptidase La

This is an abbreviated version!
For detailed information about Endopeptidase La, go to the full flat file.

Word Map on EC 3.4.21.53

Reaction

hydrolysis of proteins in presence of ATP =

Synonyms

AAA+ Lon protease, AAA+ protease, AAAP, AF0364, AfLon, archaeal Lon protease, ATP-dependent lon protease, ATP-dependent Lon proteinase, ATP-dependent PIM1 protease, ATP-dependent protease La, ATP-dependent protease lon, ATP-dependent protease LonA, ATP-dependent serine proteinase, ATP-independent Lon-like protease, bacterial protease lon, BPP1347, ClpXP, EcLon, Ec-Lon, Ec-Lon protease, EcLon, EcLon protease, ELon, Escherichia coli proteinase La, Escherichia coli serine proteinase La, Gene lon protease, Gene lon proteins, hLon, human ATP-dependent protease, human lon protease, HVO_0783, i-AAA Protease, la, La protease, lon, lon (la) protease, lon (Pim1p) protease, Lon AAA+ protease, lon ATP-dependent protease, lon protease, LON protease 1, Lon protein, Lon proteinase, lon-like protease, Lon-like-Ms, lon1, lon2, lon3, lon4, lonA, lonB, lonB protease, LonC, LonC protease, lonD, LONP1, lonR9, LONRF1, lonS, lonTK, lonV, mitochondrial ATP-dependent protease, mitochondrial ATP-dependent protease La, mitochondrial Lon protease, MLon, Ms-Lon, Msm 1754, Msm_1754, MtaLonA, MtaLonC, Nmag_2822, NmLon, non-canonical RNA viral Lon proteinase, peroxisomal Lon protease, PIM1, PIM1 protease, PIM1 proteinase, Pim1p, PLon, protease, Protease La, protease lon, Proteinase La, Proteinase, Escherichia coli serine, La, Proteinase, La, Proteins, gene lon, Proteins, specific or class, gene lon, ScLon, serine protease, Serine protease La, Ta1081, Thela2p4_005149, Thela2p4_006664, TK1264, TonLonB, TON_0529, yeast mitochondrial lon, yeast protease

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.53 Endopeptidase La

Molecular Weight

Molecular Weight on EC 3.4.21.53 - Endopeptidase La

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
100000
105000
106000
117000
-
each lon subunit has a mass of 117 kDa, heptamer
120000
122000
-
mature PIM1 protease
15060
-
analytical ultracentrifugation, monomer
25000
-
LonP, gel filtration
36000
mutants deltaTM1-lon and deltaTM2-lon
360000
-
E. coli
403000
gel filtration
420000
-
mutant enzyme, gel filtration
430000
450000
-
E. coli, gel filtration, glycerol density gradient centrifugation
525000
-
hexamer, gel filtration and sedimentation velocity analytical ultracentrifugation
549000
gel filtration
550000
-
rat, gel filtration
65856
6 * 65856, calculated
67000
-
limited tryptic digestion
68200
x * 68200, the subunit consist of ATPase and proteolytic domains
700000
72000
750000 - 850000
-
gel filtration
800000
-
E. coli, gel filtration
804000
818000
838000
-
measuring the mass of the pure enzyme complex by analytical ultracentrifugation. When purified in the presence of ATP, enzyme has a mass of 838 kDa as determined by sedimentation to equilibrium. Adding ATP is essential for preserving the Lon oligomer during ultracentrifugation
840000 - 900000
-
E. coli, calculated from sedimentation coefficient and Stokes radius
84269
x * 84269, calculated
87000
87400
88000
88800
x * 88800, calculated
89000
x * 89000, Lon, SDS-PAGE
90000
90700
x * 90700, calculated and SDS-PAGE
930000
-
dodecamer, gel filtration and sedimentation velocity analytical ultracentrifugation
94000
977000
-
predicted molecular mass of the subunit calculated from the gene
additional information