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3.4.21.53: Endopeptidase La

This is an abbreviated version!
For detailed information about Endopeptidase La, go to the full flat file.

Word Map on EC 3.4.21.53

Reaction

hydrolysis of proteins in presence of ATP =

Synonyms

AAA+ Lon protease, AAA+ protease, AAAP, AF0364, AfLon, archaeal Lon protease, ATP-dependent lon protease, ATP-dependent Lon proteinase, ATP-dependent PIM1 protease, ATP-dependent protease La, ATP-dependent protease lon, ATP-dependent protease LonA, ATP-dependent serine proteinase, ATP-independent Lon-like protease, bacterial protease lon, BPP1347, ClpXP, EcLon, Ec-Lon, Ec-Lon protease, EcLon, EcLon protease, ELon, Escherichia coli proteinase La, Escherichia coli serine proteinase La, Gene lon protease, Gene lon proteins, hLon, human ATP-dependent protease, human lon protease, HVO_0783, i-AAA Protease, la, La protease, lon, lon (la) protease, lon (Pim1p) protease, Lon AAA+ protease, lon ATP-dependent protease, lon protease, LON protease 1, Lon protein, Lon proteinase, lon-like protease, Lon-like-Ms, lon1, lon2, lon3, lon4, lonA, lonB, lonB protease, LonC, LonC protease, lonD, LONP1, lonR9, LONRF1, lonS, lonTK, lonV, mitochondrial ATP-dependent protease, mitochondrial ATP-dependent protease La, mitochondrial Lon protease, MLon, Ms-Lon, Msm 1754, Msm_1754, MtaLonA, MtaLonC, Nmag_2822, NmLon, non-canonical RNA viral Lon proteinase, peroxisomal Lon protease, PIM1, PIM1 protease, PIM1 proteinase, Pim1p, PLon, protease, Protease La, protease lon, Proteinase La, Proteinase, Escherichia coli serine, La, Proteinase, La, Proteins, gene lon, Proteins, specific or class, gene lon, ScLon, serine protease, Serine protease La, Ta1081, Thela2p4_005149, Thela2p4_006664, TK1264, TonLonB, TON_0529, yeast mitochondrial lon, yeast protease

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.53 Endopeptidase La

KM Value

KM Value on EC 3.4.21.53 - Endopeptidase La

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.026
alpha-casein
-
-
-
0.003 - 0.58
ATP
0.073
beta-galactosidase fragment 3-93
-
37°C
-
0.007
beta-galactosidase-93-titinI27
-
pH not specified in the publication, 37°C
-
0.15
diphosphate
-
(+ peptide)
0.0046
F-QLRSLNGEWRFAWFPAPEAV-Q
-
37°C
1.027
FRETN 89-98
pH 8.0, 37°C, recombinant enzyme
0.4 - 0.5
Glutaryl-Ala-Ala-Phe-methoxynaphthylamide
-
-
0.035 - 0.05
human alphaA-crystallin
-
0.026 - 0.058
human alphaB-crystallin
-
0.0022 - 0.053
human titin
-
0.017 - 0.018
IbpA
-
0.016
IbpB
-
0.016
QLRSLNGEWRFAWFPAPEAV
-
37°C
0.3
titin-I27CD
-
37°C
-
0.015
titinI27-beta-galactosidase-93
-
pH not specified in the publication, 37°C
-
0.023
titinI27-beta-galactosidase-93-titinI27
-
pH not specified in the publication, 37°C
-
0.276
Y(3-NO2)-RGIT2-aminobuytric acid-SGRQ-K(anthranilamide)
-
-
0.262
Y(3-NO2)-RGITCSGRQ-K(anthranilamide)
-
-
1.3
Y(3-NO2)-RGITCysSGRQ-K(anthranilamide)
-
-
additional information
additional information
Michaelis-Menten plot of YbeA-ssrA degradation
-