Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

3.4.21.50: lysyl endopeptidase

This is an abbreviated version!
For detailed information about lysyl endopeptidase, go to the full flat file.

Word Map on EC 3.4.21.50

Reaction

Preferential cleavage: Lys-/-, including -Lys-/-Pro- =

Synonyms

Achrombacter protease I, Achromobacter lysyl endopeptidase, Achromobacter protease I, Achromobacter proteinase I, achromopeptidase, API, caseinase, endo-Lys-C protease, endopeptidase Lys-C, endoproteinase, endoproteinase Lys-C, endoproteinase lysine-C, KGP, LEP, Lys-C, Lys-C endoproteinase, Lys-specific serine endopeptidase, lysine endoproteinase, lysine specific gingipain, lysine specific protease, lysine specific proteinase, lysine-specific protease, Lysobacter lysyl endoproteinase, lysyl bond specific proteinase, Lysyl endopeptidase, protease I, protease IV, proteinase, Achromobacter lyticus alkaline I, proteinase, lysine specific, proteinase, Pseudomonas lyticus alkaline , I, Ps-1, Pseudomonas aeruginosa lysine -specific protease

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.50 lysyl endopeptidase

Inhibitors

Inhibitors on EC 3.4.21.50 - lysyl endopeptidase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
6-amino-1-hexanoic acid
-
-
acetonitrile
-
-
antipain
benzamidine
-
0.1 mM, 21% inhibition
benzoyl-DL-lysinal
-
-
Benzoyl-Lys
-
-
benzyloxycarbonyl-Leu-Leu-lysinal
benzyloxycarbonyl-Leu-Pro-lysinal
-
-
benzyloxycarbonyl-Pro-lysinal
-
-
benzyloxycarbonyl-Val-lysinal
benzyloxycarbonyl-Val-lysinol
-
poor competitive inhibitor
Cyclohexylamine
-
-
diisopropyl fluorophosphate
diisopropylfluorophosphate
ethylamine
-
-
Guanidine-HCl
0.1 M, 20 min, 72% loss of activity
Isobutylamine
-
-
methylamine
-
-
n-alkylamine
-
-
n-amylamine
-
-
n-butylamine
-
-
n-Hexylamine
-
-
n-Propylamine
-
-
N-tosyl-L-Lys chloromethyl ketone
N-tosyl-L-Lys chloromethylketone
-
Nalpha-p-tosyl-L-Lys-chloromethylketone
Nalpha-p-tosyl-L-lysine chloromethyl ketone
-
1 mM, complete inhibition
phenylmethanesulfonyl fluoride
sodium dodecylsulfate
0.1%, 20 min, 70% loss of activity
tosyl-L-lysine chloromethylketone
-
i.e. TLCK
additional information
-