3.4.21.4: trypsin
This is an abbreviated version!
For detailed information about trypsin, go to the full flat file.
Word Map on EC 3.4.21.4
-
3.4.21.4
-
soybean
-
pancreas
-
elastase
-
pepsin
-
thrombin
-
amylase
-
proteinases
-
albumin
-
lipase
-
porcine
-
collagenase
-
pronase
-
erythrocyte
-
plasmin
-
collagen
-
kallikreins
-
sephadex
-
neuraminidase
-
bean
-
lectin
-
exocrine
-
carboxypeptidase
-
juice
-
cathepsins
-
coagulation
-
edman
-
casein
-
duodenal
-
plasminogen
-
acinar
-
aprotinin
-
cyanogen
-
subtilisin
-
zymogen
-
heparin
-
radioimmunoassay
-
midguts
-
cholecystokinin
-
reversed-phase
-
lysozyme
-
venom
-
125i-labeled
-
hydrolysates
-
protease-activated
-
kinin
-
tryptase
-
flour
-
phosphopeptides
-
hemagglutination
-
hyaluronidase
-
biotechnology
-
synthesis
-
food industry
-
medicine
-
analysis
- 3.4.21.4
- soybean
- pancreas
- elastase
- pepsin
- thrombin
- amylase
- proteinases
- albumin
- lipase
- porcine
- collagenase
- pronase
- erythrocyte
- plasmin
- collagen
- kallikreins
- sephadex
- neuraminidase
- bean
- lectin
-
exocrine
- carboxypeptidase
- juice
- cathepsins
- coagulation
-
edman
- casein
- duodenal
- plasminogen
-
acinar
- aprotinin
-
cyanogen
- subtilisin
- zymogen
- heparin
-
radioimmunoassay
- midguts
- cholecystokinin
-
reversed-phase
- lysozyme
- venom
-
125i-labeled
- hydrolysates
-
protease-activated
- kinin
- tryptase
- flour
- phosphopeptides
-
hemagglutination
- hyaluronidase
- biotechnology
- synthesis
- food industry
- medicine
- analysis
Reaction
preferential cleavage: Arg-/-, Lys-/- =
Synonyms
acrosin, alpha-trypsin, anionic salmon trypsin, anionic trypsin, Anionic trypsinogen, AST, aT-I, aT-II, Atlantic cod trypsin I, beta-trypsin, BPT, Brain trypsinogen, BT, cationic trypsin, Cationic trypsinogen, cocoonase, CST, EC 3.4.4.4, EFE, EG-T, fibrinolytic enzyme, gamma-trypsin, GM-T, group III trypsin, mesotrypsin, Mesotrypsinogen, midgut-specific serine protease 1, midgut-specific serine protease 2, More, p23, parenzyme, parenzymol, PPT, pro23, pseudotrypsin, SET, SGT, sperm receptor hydrolase, ST-1, ST-2, ST-3, TI, TIIA, TIII, TLE, TLE I, TLE II, TR-P, TR-S, tripcellim, TRP, Try, TRY-3, TryI, TryII, TryIII, TRYP, trypsin 1, trypsin 3A1, trypsin 4, trypsin A, trypsin B, trypsin I, trypsin IV, trypsin type III, trypsin Y, trypsin-1, trypsin-2, trypsin-3, trypsin-4, trypsin-like enzyme, trypsin-like serine proteinase, tryptar, tryptase, trypure, TrypZean, type I trypsin, type IX pancreatic trypsin
ECTree
3.4.21.4 trypsinAdvanced search results
results (
results (Natural Substrates Products
Natural Substrates Products on EC 3.4.21.4 - trypsin
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
DrmSP8-36 + H2O
?
-
trypsin is the major endopeptidase regulating N-terminal truncated sex peptide DrmSP8-36 in hemolymph, the trypsin cleavage site R7-K8 is essential for release of the C-terminal fragment SP8-36 from sperm tail, the protein is cleaved more rapidly and completely in mated female hemolymph
-
-
?
enhanced green fluorescent protein-T1 + H2O
?
-
enhanced green fluorescent protein-T1 is specifically cleaved into two major fragments by trypsin at the grafted cleavage site, approximately 20 and 8 kDa
-
-
?
enhanced green fluorescent protein-T2 + H2O
?
-
enhanced green fluorescent protein-T2 is specifically cleaved into two major fragments by trypsin at the grafted cleavage site, approximately 18 and 10 kDa
-
-
?
human cartilage collagen type II + H2O
?
-
use of enzyme and its regulators as markers of prognosis and disease activity in rheumatoid arthritis
-
-
?
intestinal alkaline sphingomyelinase bound to mucosa + H2O
free intestinal alkaline sphingomyelinase
-
cleavage at R440, first tryptic site upstream of signal anchor. Physiological role of enzyme in sphingomyelin digestion
-
-
?
additional information
?
-
-
trypsin treatment increases zone of polarizing activity signaling of non-zone of polarizing activity tissue
-
-
?
additional information
?
-
-
trypsin is involved in the progesterone-induced acrosome reaction in canine spermatozoa
-
-
?
additional information
?
-
-
trypsin-catalyzed peptide synthesis with inverse substrates as acyl donor components, overview
-
-
?
additional information
?
-
-
capable of agglutinating both bloodstream-form and procyclic trypanosomes as well as rabbit red blood cells
-
-
?
additional information
?
-
-
enzyme pancreatic isoforms cationic trypsin and anionic trypsin show activity on human proteinase-activated receptors PAR-1, PAR-2, PAR-3 comparable to that of bovine pancreatic trypsin. Mesotrypsin cannot activate or disable proteinase-activated receptors in human epithelial cells, but activates PAR-1 in human astrocytoma cells
-
-
?
additional information
?
-
-
active 1918 pandemic flu viral neuraminidase is resistant to trypsin digestion
-
-
?
additional information
?
-
-
does not cleave enhanced green fluorescent protein-T1m and wild type enhanced green fluorescent protein
-
-
?
additional information
?
-
trypsin specifically cleaves the peptide bond on the carboxyl side of Lys and Arg residues. It is characterized by a common catalytic mechanism involving the catalytic triad of three essential amino acid residues His57, Asp102, and Ser195 and a substrate determinant residue Asp189
-
-
?
additional information
?
-
-
trypsin treatment alters a number of characteristics of KATP channel pharmacology, this may be due to action at possibly more than one site but includes the functional cleavage of the sulfonylurea receptor from the KATP channel
-
-
?
additional information
?
-
-
salmon trypsin induces interleukin-8 production in human airway epithelial cells, purified salmon trypsin activates nuclear factor-kappa B-mediated gene expression in HeLa cells overexpressing human protease-activated receptor-2, the production of interleukin-8 by salmon trypsin is mediated by protease-activated receptor-2
-
-
?
