3.4.21.4: trypsin

This is an abbreviated version!
For detailed information about trypsin, go to the full flat file.

Reaction

preferential cleavage: Arg-/-, Lys-/- =

Synonyms

acrosin, alpha-trypsin, anionic salmon trypsin, anionic trypsin, Anionic trypsinogen, AST, aT-I, aT-II, Atlantic cod trypsin I, beta-trypsin, BPT, Brain trypsinogen, BT, cationic trypsin, Cationic trypsinogen, cocoonase, CST, EC 3.4.4.4, EFE, EG-T, fibrinolytic enzyme, gamma-trypsin, GM-T, group III trypsin, mesotrypsin, Mesotrypsinogen, midgut-specific serine protease 1, midgut-specific serine protease 2, More, p23, parenzyme, parenzymol, PPT, pro23, pseudotrypsin, SET, SGT, sperm receptor hydrolase, ST-1, ST-2, ST-3, TI, TIIA, TIII, TLE, TLE I, TLE II, TR-P, TR-S, tripcellim, TRP, Try, TRY-3, TryI, TryII, TryIII, TRYP, trypsin 1, trypsin 3A1, trypsin 4, trypsin A, trypsin B, trypsin I, trypsin IV, trypsin type III, trypsin Y, trypsin-1, trypsin-2, trypsin-3, trypsin-4, trypsin-like enzyme, trypsin-like serine proteinase, tryptar, tryptase, trypure, TrypZean, type I trypsin, type IX pancreatic trypsin

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.21 Serine endopeptidases

                3.4.21.4 trypsin

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
18	Activating Compound
676	AA Sequence
20	Application
1	CAS Registry Number
24	Cloned(Commentary)
38	Crystallization (Commentary)
12526	Disease/ Diagnostics
1	Expression
20	General Information
28	General Stability
9	IC50 Value
419	Inhibitors
64	kcat/KM [mM/s]
70	Ki Value [mM]
400	KM Value [mM]
3	Localization
34	Metals/Ions
92	Molecular Weight [Da]
21	Natural Substrates/ Products (Substrates)
8	Organic Solvent Stability
308	Organism
1	Oxidation Stability
1	Pathway
853	PDB ID
90	pH Optimum
27	pH Range
41	pH Stability
17	pI Value
18	Posttranslational Modification
44	Protein Variants
80	Purification (Commentary)
3	Reaction
2	Reaction Type
306	Reference
3	Renatured (Commentary)
230	Source Tissue
58	Specific Activity [micromol/min/mg]
6	Storage Stability
618	Substrates and Products (Substrate)
51	Subunits
102	Synonyms
69	Temperature Optimum [°C]
19	Temperature Range [°C]
58	Temperature Stability [°C]
375	Turnover Number [1/s]

IC50 Value

print visible entries

print all entries

IC50 Value on EC 3.4.21.4 - trypsin

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to IC50 Value Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

IC50 VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.0003

1-[N2-[(7-methoxynaphthalen-2-yl)sulfonyl]-L-arginyl]-4-phenylpiperidine-2-carboxylic acid

Bos taurus

P00760

IC50: 0.0003 mM

652004

0.04

antipain

Bos taurus

P00760

IC50: 0.04 mM

652004

0.0002

leupeptin

Bos taurus

P00760

IC50: 0.0002 mM

652004

0.0013

lily bulb trypsin inhibitor

Bos taurus

-

in 50 M Tris-HCl (pH 8.0), at 25°C

700850

-

0.00008

mustard trypsin inhibitor 2

Plutella xylostella

-

in 100 mM Tris-HCl, pH 8

698283

-

0.00003

nafamostat mesilate

Bos taurus

P00760

IC50: 0.00003 mM

652004

0.019

small glossy black soybean trypsin inhibitor

Bos taurus

-

in 0.1 M Tris-HCl (pH 7.4), at 37°C

694789

-

0.000006

soybean Kunitz trypsin inhibitor

Plutella xylostella

-

in 100 mM Tris-HCl, pH 8

698283

-

0.000009

Soybean trypsin inhibitor

Bos taurus

P00760

IC50: 0.000009 mM

652004

-