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3.4.21.38: coagulation factor XIIa

This is an abbreviated version!
For detailed information about coagulation factor XIIa, go to the full flat file.

Word Map on EC 3.4.21.38

Reaction

selective cleavage of Arg-/-Ile bonds in factor VII to form factor VIIa and factor XI to form factor XIa =

Synonyms

activated coagulation factor XII, activated factor XII, alpha-FXIIa, alphaFXIIa, beta-factor XIIa, beta-FXIIa, blood coagulation factor XII, blood-coagulation factor XII, activated beta, blood-coagulation factor XIIabeta, blood-coagulation factor XIIf, coagulation beta-factor XIIa, coagulation factor XII, coagulation factor XIIa, F12, factor XII, factor XII Osaka, factor XIIa, FXII, FXIIa, HAF, Hageman factor, Hageman factor beta-fragment, Hageman factor fragment HFf, Hagemann factor, kallikreinogen, activator, prealbumin activator, prekallikrein activator, single-chain FXII

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.38 coagulation factor XIIa

Reference

Reference on EC 3.4.21.38 - coagulation factor XIIa

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Davie, E.W.; Fujikawa, K.; Kurachi, K.; Kisiel, W.
The role of serine proteases in the blood coagulation cascade
Adv. Enzymol. Relat. Areas Mol. Biol.
48
277-318
1979
Bos taurus
Manually annotated by BRENDA team
McMullen, B.A.; Fujikawa, K.
Amino acid sequence of the heavy chain of human alpha-factor XIIa (activated Hageman factor)
J. Biol. Chem.
260
5328-5341
1985
Homo sapiens
Manually annotated by BRENDA team
Silverberg, M.; Kaplan, A.P.
Enzymatic activities of activated and zymogen forms of human Hageman factor (factor XII)
Blood
60
64-70
1982
Homo sapiens
Manually annotated by BRENDA team
Hojima, Y.; Pierce, J.V.; Pisano, J.J.
Pumpkin seed inhibitor of human factor XIIa (activated Hageman factor) and bovine trypsin
Biochemistry
21
3741-3746
1982
Homo sapiens
Manually annotated by BRENDA team
Semba, U.; Yamamoto, T.; Kunisada, T.; Shibuya, Y.; Tanase, S.; Kambara, T.; Okabe, H.
Primary structure of guinea-pig Hageman factor: sequence around the cleavage site differs from the human molecule
Biochim. Biophys. Acta
1159
113-121
1992
Cavia porcellus, Homo sapiens
Manually annotated by BRENDA team
Fujikawa, K.; Kurachi, K.; Davie, E.W.
Characterization of bovine factor XIIa (activated Hageman factor)
Biochemistry
16
4182-4188
1977
Bos taurus
Manually annotated by BRENDA team
Kisiel, W.; Fujikawa, K.; Davie, E.W.
Activation of bovine factor VII (proconvertin) by factor XIIa (activated Hageman factor)
Biochemistry
16
4189-4194
1977
Bos taurus
Manually annotated by BRENDA team
Kurachi, K.; Davie, E.W.
Activation of human factor XI (plasma thromboplastin antecedent) by factor XIIa (activated Hageman factor)
Biochemistry
16
5831-5839
1977
Bos taurus
Manually annotated by BRENDA team
Ratnoff, O.D.; Saito, H.
Amidolytic properties of single-chain activated Hageman factor
Proc. Natl. Acad. Sci. USA
76
1461-1463
1979
Homo sapiens
Manually annotated by BRENDA team
Que, B.G.; Davie, E.W.
Characterization of a cDNA coding for human factor XII (Hageman Factor)
Biochemistry
25
1525-1528
1986
Homo sapiens
Manually annotated by BRENDA team
Cho, K.; Tanaka, T.; Cook, R.R.; Kisiel, W.; Fujikawa, K.; Kurachi, K.
Active-site mapping of bovine and human blood coagulation serine proteases using synthetic peptide 4-nitroanilide and thio ester substrates
Biochemistry
23
644-650
1984
Homo sapiens
Manually annotated by BRENDA team
Loiseau, C.; Randriamahazaka, H.N.; Nigretto, J.M.
Explicit constants for the dextran-sulfate-mediated activation and autoactivation of purified human factor XII (Hageman factor)
Eur. J. Biochem.
239
692-701
1996
Homo sapiens
Manually annotated by BRENDA team
Gordon, E.M.; Johnson, T.R.; Ramos, L.P.; Schmeidler-Sapiro, K.T.
Enhanced expression of factor XII (Hageman factor) in isolated livers of estrogen- and prolacton-treated rats
J. Lab. Clin. Med.
117
353-358
1991
Rattus norvegicus
Manually annotated by BRENDA team
Nuijens, J.H.; Huijbregts, C.C.M.; Eerenberg-Belmer, A.J.M.; Meijers, J.C.M.; Bouma, B.N.; Hack, C.E.
Activation of the contact system of coagulation by a monoclonal antibody directed against a neodeterminant in the heavy chain region of human coagulation factor XII (Hageman factor)
J. Biol. Chem.
264
12941-12949
1989
Homo sapiens
Manually annotated by BRENDA team
Real, K.J.; Masterson, B.F.
Availability in pooled normal blood plasma of activated Hageman factor and kallikrein for contact induced coagulation
Biochem. Soc. Trans.
26
S274
1998
Homo sapiens
Manually annotated by BRENDA team
Samuel, M.; Samuel, E.; Villanueva, G.B.
The low pH stability of human coagulation factor XII (Hageman factor) is due to reversible conformational transitions
Thromb. Res.
75
259-268
1994
Homo sapiens
Manually annotated by BRENDA team
Gordon, E.M.; Gallagher, C.A.; Johnson, T.R.; Blossey, B.K.; Ilan, J.
Hepatocytes express blood coagulation factor XII (Hageman factor)
J. Lab. Clin. Med.
115
463-469
1990
Rattus norvegicus
Manually annotated by BRENDA team
Fujikawa, K.; Davie, E.W.
Human factor XII (Hageman factor)
Methods Enzymol.
80
198-211
1981
Homo sapiens
Manually annotated by BRENDA team
Fujikawa, K.
Bovine Hageman factor and its fragments
Methods Enzymol.
163
54-68
1988
Bos taurus
Manually annotated by BRENDA team
Silverberg, M.; Kaplan, A.P.
Human Hageman factor and its fragments
Methods Enzymol.
163
68-80
1988
Homo sapiens
Manually annotated by BRENDA team
Yamamoto, T.; Shibuya, Y.; Nishino, N.; Okabe, H.; Kambara, T.
Activation of human Hageman factor by Pseudomonas aeruginosa elastase in the presence or absence of negatively charged substance in vitro
Biochim. Biophys. Acta
1038
231-239
1990
Homo sapiens
Manually annotated by BRENDA team
Shan, J.; Baguinon, M.; Zheng, L.; Krishnamoorthi, R.
Expression, refolding, and activation of the catalytic domain of human blood coagulation factor XII
Protein Expr. Purif.
27
143-149
2003
Homo sapiens
Manually annotated by BRENDA team
Carmona, F.; Lazaro, I.; Reverter, J.C.; Tassies, D.; Font, J.; Cervera, R.; Balasch, J.
Impaired factor XIIa-dependent activation of fibrinolysis in treated antiphospholipid syndrome gestations developing late-pregnancy complications
Am. J. Obstet. Gynecol.
194
457-465
2006
Homo sapiens
Manually annotated by BRENDA team
Lowe, G.D.; Rumley, A.; McMahon, A.D.; Ford, I.; OReilly, D.S.; Packard, C.J.; Packard, C.J.
Interleukin-6, fibrin D-dimer, and coagulation factors VII and XIIa in prediction of coronary heart disease
Arterioscler. Thromb. Vasc. Biol.
24
1529-1534
2004
Homo sapiens
Manually annotated by BRENDA team
Johne, J.; Blume, C.; Benz, P.M.; Pozgajova, M.; Ullrich, M.; Schuh, K.; Nieswandt, B.; Walter, U.; Renne, T.
Platelets promote coagulation factor XII-mediated proteolytic cascade systems in plasma
Biol. Chem.
387
173-178
2006
Homo sapiens
Manually annotated by BRENDA team
Kleinschnitz, C.; Stoll, G.; Bendszus, M.; Schuh, K.; Pauer, H.U.; Burfeind, P.; Renne, C.; Gailani, D.; Nieswandt, B.; Renne, T.
Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis
J. Exp. Med.
203
513-518
2006
Mus musculus
Manually annotated by BRENDA team
Ebbesen, L.S.; Ingerslev, J.
Folate deficiency-induced hyperhomocysteinemia attenuates, and folic acid supplementation restores, the functional activities of rat coagulation factors XII, X, and II
J. Nutr.
135
1836-1840
2005
Rattus norvegicus
Manually annotated by BRENDA team
Latacha, M.P.; Schaiff, W.T.; Eisenberg, P.R.; Abendschein, D.R.
Factor XII-dependent increases in thrombin activity induce carboxypeptidase-mediated attenuation of pharmacological fibrinolysis
J. Thromb. Haemost.
2
128-134
2004
Homo sapiens
Manually annotated by BRENDA team
Schousboe, I.
Endothelial cells express a matrix protein which binds activated factor XII in a zinc-independent manner
Thromb. Haemost.
95
312-319
2006
Homo sapiens
Manually annotated by BRENDA team
Gallimore, M.J.; Harris, S.L.; Jones, D.W.; Winter, M.
Plasma levels of factor XII, prekallikrein and high molecular weight kininogen in normal blood donors and patients having suffered venous thrombosis
Thromb. Res.
114
91-96
2004
Homo sapiens
Manually annotated by BRENDA team
Amfilochiadis, A.A.; Backx, P.H.; Floras, J.S.
Adrenomedullary catecholamine, pressor and chronotropic responses to human coagulation beta-FXIIa mediated by endogenous kinins
J. Hypertens.
26
61-69
2008
Rattus norvegicus (D3ZTE0)
Manually annotated by BRENDA team
Poenitz, V.; Pritchard, D.; Grundt, H.; Nilsen, D.W.
Specific types of activated Factor XII increase following thrombolytic therapy with tenecteplase
J. Thromb. Thrombolysis
22
199-203
2006
Homo sapiens (P00748), Homo sapiens
Manually annotated by BRENDA team
Kravtsov, D.V.; Matafonov, A.; Tucker, E.I.; Sun, M.F.; Walsh, P.N.; Gruber, A.; Gailani, D.
Factor XI contributes to thrombin generation in the absence of factor XII
Blood
114
452-458
2009
Homo sapiens
Manually annotated by BRENDA team
Matsubayashi, H.; Sugi, T.; Suzuki, T.; Uchida, N.; Atsumi, H.; Izumi, S.; Mikami, M.
Decreased factor XII activity is associated with recurrent IVF-ET failure
Am. J. Reprod. Immunol.
59
316-322
2008
Homo sapiens
Manually annotated by BRENDA team
Barbasz, A.; Kozik, A.
The assembly and activation of kinin-forming systems on the surface of human U-937 macrophage-like cells
Biol. Chem.
390
269-275
2009
Homo sapiens
Manually annotated by BRENDA team
Lombardi, A.M.; Bortoletto, E.; Scarparo, P.; Scapin, M.; Santarossa, L.; Girolami, A.
Genetic study in patients with factor XII deficiency: a report of three new mutations exon 13 (Q501STOP), exon 14 (P547L) and -13C>T promoter region in three compound heterozygotes
Blood Coagul. Fibrinolysis
19
639-643
2008
Homo sapiens
Manually annotated by BRENDA team
Okorie, U.M.; Denney, W.S.; Chatterjee, M.S.; Neeves, K.B.; Diamond, S.L.
Determination of surface tissue factor thresholds that trigger coagulation at venous and arterial shear rates: amplification of 100 fM circulating tissue factor requires flow
Blood
111
3507-3513
2008
Homo sapiens
Manually annotated by BRENDA team
Stoll, G.; Kleinschnitz, C.; Nieswandt, B.
Molecular mechanisms of thrombus formation in ischemic stroke: novel insights and targets for treatment
Blood
112
3555-3562
2008
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Schousboe, I.; Nystrom, B.T.; Hansen, G.H.
Differential binding of factor XII and activated factor XII to soluble and immobilized fibronectin--localization of the Hep-1/Fib-1 binding site for activated factor XII
FEBS J.
275
5161-5172
2008
Homo sapiens
Manually annotated by BRENDA team
Schmaier, A.H.
The elusive physiologic role of Factor XII
J. Clin. Invest.
118
3006-3009
2008
Homo sapiens
Manually annotated by BRENDA team
Davis, A.E.; Mejia, P.; Lu, F.
Biological activities of C1 inhibitor
Mol. Immunol.
45
4057-4063
2008
Homo sapiens
Manually annotated by BRENDA team
Reuner, K.H.; Jenetzky, E.; Aleu, A.; Litfin, F.; Mellado, P.; Kloss, M.; Juettler, E.; Grau, A.J.; Rickmann, H.; Patscheke, H.; Lichy, C.
Factor XII C46T gene polymorphism and the risk of cerebral venous thrombosis
Neurology
70
129-132
2008
Homo sapiens
Manually annotated by BRENDA team
Kleinschnitz, C.; Braeuninger, S.; Pham, M.; Austinat, M.; Noelte, I.; Renne, T.; Nieswandt, B.; Bendszus, M.; Stoll, G.
Blocking of platelets or intrinsic coagulation pathway-driven thrombosis does not prevent cerebral infarctions induced by photothrombosis
Stroke
39
1262-1268
2008
Mus musculus
Manually annotated by BRENDA team
Melo, F.R.; Mourao, P.A.
An algal sulfated galactan has an unusual dual effect on venous thrombosis due to activation of factor XII and inhibition of the coagulation proteases
Thromb. Haemost.
99
531-538
2008
Homo sapiens
Manually annotated by BRENDA team
Fonseca, R.J.; Oliveira, S.N.; Melo, F.R.; Pereira, M.G.; Benevides, N.M.; Mourao, P.A.
Slight differences in sulfation of algal galactans account for differences in their anticoagulant and venous antithrombotic activities
Thromb. Haemost.
99
539-545
2008
Rattus norvegicus
Manually annotated by BRENDA team
Fink, H.; Faxaelv, L.; Molnar, G.F.; Drotz, K.; Risberg, B.; Lindahl, T.L.; Sellborn, A.
Real-time measurements of coagulation on bacterial cellulose and conventional vascular graft materials
Acta Biomater.
6
1125-1130
2010
Homo sapiens
Manually annotated by BRENDA team
Vogler, E.A.; Siedlecki, C.A.
Contact activation of blood-plasma coagulation
Biomaterials
30
1857-1869
2009
Bos taurus, Equus caballus, Gallus gallus, Homo sapiens
Manually annotated by BRENDA team
Chatterjee, K.; Thornton, J.L.; Bauer, J.W.; Vogler, E.A.; Siedlecki, C.A.
Moderation of prekallkrein-factor XII interactions in surface activation of coagulation by protein-adsorption competition
Biomaterials
30
4915-4920
2009
Homo sapiens
Manually annotated by BRENDA team
Bork, K.; Kleist, R.; Hardt, J.; Witzke, G.
Kallikrein-kinin system and fibrinolysis in hereditary angioedema due to factor XII gene mutation Thr309Lys
Blood Coagul. Fibrinolysis
20
325-332
2009
Homo sapiens
Manually annotated by BRENDA team
Kwon, M.J.; Kim, H.J.; Lee, K.O.; Jung, C.W.; Kim, S.H.
Molecular genetic analysis of Korean patients with coagulation factor XII deficiency
Blood Coagul. Fibrinolysis
21
308-312
2010
Homo sapiens (P00748), Homo sapiens
Manually annotated by BRENDA team
Papageorgiou, P.C.; Simos, D.; Boomsma, F.; Rojkjaer, R.; Osmond, D.H.
Angiotensin converting enzyme-regulated, noncholinergic sympathoadrenal catecholamine release mediates the cardiovascular actions of human new pressor protein related to coagulation beta-factor XIIa
Can. J. Cardiol.
25
e100-e108
2009
Homo sapiens
Manually annotated by BRENDA team
Kraft, P.; Schwarz, T.; Pochet, L.; Stoll, G.; Kleinschnitz, C.
COU254, a specific 3-carboxamide-coumarin inhibitor of coagulation factor XII, does not protect mice from acute ischemic stroke
Exp. Transl. Stroke Med.
2
5
2010
Mus musculus, Mus musculus C57BL/6
Manually annotated by BRENDA team
Wang, R.; Zhang, T.; Ma, Z.; Wang, Y.; Cheng, Z.; Xu, H.; Li, W.; Wang, X.
The interaction of coagulation factor XII and monocyte/macrophages mediating peritoneal metastasis of epithelial ovarian cancer
Gynecol. Oncol.
117
460-466
2010
Homo sapiens
Manually annotated by BRENDA team
Jablonska, E.; Markart, P.; Zakrzewicz, D.; Preissner, K.T.; Wygrecka, M.
Transforming growth factor-beta1 induces expression of human coagulation factor XII via Smad3 and JNK signaling pathways in human lung fibroblasts
J. Biol. Chem.
285
11638-11651
2010
Homo sapiens
Manually annotated by BRENDA team
Chatterjee, K.; Guo, Z.; Vogler, E.; Siedlecki, C.
Contributions of contact activation pathways of coagulation factor XII in plasma
J. Biomed. Mater. Res. A
90
27-34
2009
Homo sapiens
Manually annotated by BRENDA team
Decrem, Y.; Rath, G.; Blasioli, V.; Cauchie, P.; Robert, S.; Beaufays, J.; Frere, J.M.; Feron, O.; Dogne, J.M.; Dessy, C.; Vanhamme, L.; Godfroid, E.
Ir-CPI, a coagulation contact phase inhibitor from the tick Ixodes ricinus, inhibits thrombus formation without impairing hemostasis
J. Exp. Med.
206
2381-2395
2009
Homo sapiens, Mus musculus, Rattus norvegicus
Manually annotated by BRENDA team
Pham, M.; Kleinschnitz, C.; Helluy, X.; Bartsch, A.J.; Austinat, M.; Behr, V.C.; Renne, T.; Nieswandt, B.; Stoll, G.; Bendszus, M.
Enhanced cortical reperfusion protects coagulation factor XII-deficient mice from ischemic stroke as revealed by high-field MRI
Neuroimage
49
2907-2914
2010
Mus musculus
Manually annotated by BRENDA team
Suzuki, K.; Murai, K.; Suwabe, A.; Ishida, Y.
Factor XII Ofunato: Lys346Asn mutation associated with blood coagulation factor XII deficiency causes impaired secretion through a proteasome-mediated degradation
Thromb. Res.
125
438-443
2010
Homo sapiens
Manually annotated by BRENDA team
Bäck, J.; Sanchez, J.; Elgue, G.; Ekdahl, K.; Nilsson, B.
Activated human platelets induce factor XIIa-mediated contact activation
Biochem. Biophys. Res. Commun.
391
11-17
2010
Homo sapiens
Manually annotated by BRENDA team
Cheng, Q.; Tucker, E.; Pine, M.; Sisler, I.; Matafonov, A.; Sun, M.; White-Adams, T.; Smith, S.; Hanson, S.; McCarty, O.; Renne, T.; Gruber, A.; Gailani, D.
A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo
Blood
116
3981-3989
2010
Mus musculus
Manually annotated by BRENDA team
MacQuarrie, J.L.; Stafford, A.R.; Yau, J.W.; Leslie, B.A.; Vu, T.T.; Fredenburgh, J.C.; Weitz, J.I.
Histidine-rich glycoprotein binds factor XIIa with high affinity and inhibits contact-initiated coagulation
Blood
117
4134-4141
2011
Homo sapiens
Manually annotated by BRENDA team
Pham, M.; Stoll, G.; Nieswandt, B.; Bendszus, M.; Kleinschnitz, C.
Blood coagulation factor XII-a neglected player in stroke pathophysiology
J. Mol. Med.
90
119-126
2011
Mus musculus, Mus musculus (P00748)
Manually annotated by BRENDA team
Iijima, K.; Arakawa, Y.; Sugahara, Y.; Matsushita, M.; Moriguchi, Y.; Shimohiro, H.; Nakagawa, M.
Factor XII Osaka: Abnormal factor XII with partially defective prekallikrein cleavage activity
Thromb. Haemost.
105
473-478
2011
Homo sapiens
Manually annotated by BRENDA team
Kuijpers, M.J.; van der Meijden, P.E.; Feijge, M.A.; Mattheij, N.J.; May, F.; Govers-Riemslag, J.; Meijers, J.C.; Heemskerk, J.W.; Renne, T.; Cosemans, J.M.
Factor XII regulates the pathological process of thrombus formation on ruptured plaques
Arterioscler. Thromb. Vasc. Biol.
34
1674-1680
2014
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Papageorgiou, P.C.; Yeo, E.L.; Backx, P.H.; Floras, J.S.
Activated plasma coagulation beta-factor XII-induced vasoconstriction in rats
Clin. Sci.
122
581-590
2012
Rattus norvegicus
Manually annotated by BRENDA team
Van Der Meijden, P.E.; Van Schilfgaarde, M.; Van Oerle, R.; Renne, T.; ten Cate, H.; Spronk, H.M.
Platelet- and erythrocyte-derived microparticles trigger thrombin generation via factor XIIa
J. Thromb. Haemost.
10
1355-1362
2012
Homo sapiens
Manually annotated by BRENDA team
Puy, C.; Tucker, E.I.; Wong, Z.C.; Gailani, D.; Smith, S.A.; Choi, S.H.; Morrissey, J.H.; Gruber, A.; McCarty, O.J.
Factor XII promotes blood coagulation independent of factor XI in the presence of long-chain polyphosphates
J. Thromb. Haemost.
11
1341-1352
2013
Homo sapiens (P00748)
Manually annotated by BRENDA team
Sylman, J.; Daalkhaijav, U.; Zhang, Y.; Gray, E.; Farhang, P.; Chu, T.; Zilberman-Rudenko, J.; Puy, C.; Tucker, E.; Smith, S.; Morrissey, J.; Walker, T.; Nan, X.; Gruber, A.; McCarty, O.
Differential roles for the coagulation factors XI and XII in regulating the physical biology of fibrin
Ann. Biomed. Eng.
45
1328-1340
2017
Homo sapiens
Manually annotated by BRENDA team
Ivanov, I.; Matafonov, A.; Sun, M.F.; Cheng, Q.; Dickeson, S.K.; Verhamme, I.M.; Emsley, J.; Gailani, D.
Proteolytic properties of single-chain factor XII a mechanism for triggering contact activation
Blood
129
1527-1537
2017
Homo sapiens
Manually annotated by BRENDA team
Dementiev, A.; Silva, A.; Yee, C.; Li, Z.; Flavin, M.T.; Sham, H.; Partridge, J.R.
Structures of human plasma beta-factor XIIa cocrystallized with potent inhibitors
Blood Adv.
2
549-558
2018
Homo sapiens (P00748), Homo sapiens
Manually annotated by BRENDA team
Didiasova, M.; Wujak, L.; Schaefer, L.; Wygrecka, M.
Factor XII in coagulation, inflammation and beyond
Cell. Signal.
51
257-265
2018
Mus musculus
Manually annotated by BRENDA team
Ivanov, I.; Matafonov, A.; Gailani, D.
Single-chain factor XII a new form of activated factor XII
Curr. Opin. Hematol.
24
411-418
2017
Homo sapiens
Manually annotated by BRENDA team
Wujak, L.; Didiasova, M.; Zakrzewicz, D.; Frey, H.; Schaefer, L.; Wygrecka, M.
Heparan sulfate proteoglycans mediate factor XIIa binding to the cell surface
J. Biol. Chem.
290
7027-7039
2015
Homo sapiens
Manually annotated by BRENDA team
Stroo, I.; Zeerleder, S.; Ding, C.; Luken, B.M.; Roelofs, J.J.T.H.; de Boer, O.J.; Meijers, J.C.M.; Castellino, F.J.; van t Veer, C.; van der Poll, T.
Coagulation factor XI improves host defence during murine pneumonia-derived sepsis independent of factor XII activation
Thromb. Haemost.
117
1601-1614
2017
Mus musculus
Manually annotated by BRENDA team
Hess, R.; Wujak, L.; Hesse, C.; Sewald, K.; Jonigk, D.; Warnecke, G.; Fieguth, H.G.; de Maat, S.; Maas, C.; Bonella, F.; Preissner, K.T.; Weiss, B.; Schaefer, L.; Kuebler, W.M.; Markart, P.; Wygrecka, M.
Coagulation factor XII regulates inflammatory responses in human lungs
Thromb. Haemost.
117
1896-1907
2017
Homo sapiens
Manually annotated by BRENDA team
Konings, J.; Hoving, L.R.; Ariens, R.S.; Hethershaw, E.L.; Ninivaggi, M.; Hardy, L.J.; de Laat, B.; Ten Cate, H.; Philippou, H.; Govers-Riemslag, J.W.
The role of activated coagulation factor XII in overall clot stability and fibrinolysis
Thromb. Res.
136
474-480
2015
Homo sapiens
Manually annotated by BRENDA team