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3.4.21.38: coagulation factor XIIa

This is an abbreviated version!
For detailed information about coagulation factor XIIa, go to the full flat file.

Word Map on EC 3.4.21.38

Reaction

selective cleavage of Arg-/-Ile bonds in factor VII to form factor VIIa and factor XI to form factor XIa =

Synonyms

activated coagulation factor XII, activated factor XII, alpha-FXIIa, alphaFXIIa, beta-factor XIIa, beta-FXIIa, blood coagulation factor XII, blood-coagulation factor XII, activated beta, blood-coagulation factor XIIabeta, blood-coagulation factor XIIf, coagulation beta-factor XIIa, coagulation factor XII, coagulation factor XIIa, F12, factor XII, factor XII Osaka, factor XIIa, FXII, FXIIa, HAF, Hageman factor, Hageman factor beta-fragment, Hageman factor fragment HFf, Hagemann factor, kallikreinogen, activator, prealbumin activator, prekallikrein activator, single-chain FXII

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.38 coagulation factor XIIa

Natural Substrates Products

Natural Substrates Products on EC 3.4.21.38 - coagulation factor XIIa

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
factor VII + H2O
?
show the reaction diagram
-
enzyme is involved in the blood coagulation cascade
-
-
?
factor XI + H2O
?
show the reaction diagram
-
enzyme is involved in the blood coagulation cascade
-
-
?
factor XI + H2O
factor XIa + ?
show the reaction diagram
plasma prekallikrein + H2O
plasma kallikrein + ?
show the reaction diagram
-
-
-
-
?
plasminogen + H2O
plasmin + ?
show the reaction diagram
-
-
-
-
?
prekallikrein + H2O
kallikrein + ?
show the reaction diagram
prekallikrein + H2O
kallikrein + kallikrein prepeptide
show the reaction diagram
additional information
?
-