3.4.21.22: coagulation factor IXa
This is an abbreviated version!
For detailed information about coagulation factor IXa, go to the full flat file.
Word Map on EC 3.4.21.22
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3.4.21.22
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hemophilia
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bleeding
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clot
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prothrombin
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thrombin
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thromboplastin
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anticoagulant
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platelet
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thrombosis
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antithrombin
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viiia
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x-linked
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heparin
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adeno-associated
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fibrinogen
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plasma-derived
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willebrand
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prophylaxis
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k-dependent
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infusions
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prophylactic
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hemostatic
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zymogen
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procoagulant
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haemostasis
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fixa
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thrombogenicity
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gamma-carboxyglutamic
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one-stage
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coagulopathy
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thromboembolic
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anti-factor
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amidolytic
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on-demand
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high-purity
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fibrinopeptide
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d-dimer
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thrombin-antithrombin
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exosite
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arthropathy
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prekallikrein
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cryoprecipitate
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medicine
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gamma-carboxylation
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rfviia
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bethesda
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alloantibodies
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prothrombinase
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thrombin-activated
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diathesis
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novoseven
- 3.4.21.22
- hemophilia
- bleeding
- clot
- prothrombin
- thrombin
- thromboplastin
-
anticoagulant
- platelet
- thrombosis
- antithrombin
- viiia
-
x-linked
- heparin
-
adeno-associated
- fibrinogen
-
plasma-derived
- willebrand
-
prophylaxis
-
k-dependent
-
infusions
-
prophylactic
-
hemostatic
- zymogen
-
procoagulant
-
haemostasis
- fixa
-
thrombogenicity
-
gamma-carboxyglutamic
-
one-stage
- coagulopathy
-
thromboembolic
-
anti-factor
-
amidolytic
-
on-demand
-
high-purity
-
fibrinopeptide
-
d-dimer
-
thrombin-antithrombin
-
exosite
- arthropathy
- prekallikrein
-
cryoprecipitate
- medicine
-
gamma-carboxylation
- rfviia
-
bethesda
-
alloantibodies
- prothrombinase
-
thrombin-activated
- diathesis
- novoseven
Reaction
Selective cleavage of Arg-/-Ile bond in factor X to form factor Xa =
Synonyms
activated Christmas factor, activated coagulation factor IX, activated factor IX, activated FIX, blood coagulation factor IXa, Christmas factor, circulating factor IXa, coagulation factor IX, coagulation factor IXa, factor IX, factor IXa, factor IXaAL, factor IXaalpha, factor IXabeta, factor IXabeta', factor IXaCH, factor IXalphabeta, factor IXaN, factor XIa, FIX, FIXa, FIXC, Gla-domainless factor IXabeta', human coagulation factor IXa, intrinsic Xase, More
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Posttranslational Modification
Posttranslational Modification on EC 3.4.21.22 - coagulation factor IXa
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proteolytic modification
activation by purified factor X activator from the venom of Russells Vipe cleaving fIX after Arg180 to generate active enzyme fIXaalpha
proteolytic modification
proteolytic cleavages at two peptide bonds after Arg145 and Arg180 by either one of two physiological activators, the factor VIIa-tissue factor complex or factor XIa, leads to removal of the activation peptide and conversion of fIX to a fully active enzyme consisting of a light and a heavy chain held together by a single disulfie bond
proteolytic modification
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purified factor IX is activated with human factor XIa