3.4.21.20: cathepsin G
This is an abbreviated version!
For detailed information about cathepsin G, go to the full flat file.
Word Map on EC 3.4.21.20
-
3.4.21.20
-
elastase
-
neutrophil
-
leukocyte
-
proteinases
-
granule
-
polymorphonuclear
-
myeloperoxidase
-
chymase
-
granulocyte
-
thrombin
-
platelet
-
mast
-
azurophilic
-
serpins
-
plasmin
-
lactoferrin
-
collagenase
-
neutrophil-derived
-
granzyme
-
kallikrein
-
1-proteinase
-
degranulation
-
tryptase
-
antineutrophil
-
1-antichymotrypsin
-
eglin
-
drug development
-
nsp4
-
antiproteinases
-
2-macroglobulin
-
fmlp
-
hne
-
alpha-chymotrypsin
-
wegener
-
chediak-higashi
-
antiprotease
-
elastolytic
-
chymostatin
-
slpi
-
elastase-like
-
p-anca
-
procollagenase
-
alpha1-proteinase
-
pharmacology
-
pmn-derived
-
elafin
-
1-antitrypsin
-
medicine
-
granulomatosis
-
alpha1-antichymotrypsin
-
anti-cathepsin
-
neutrophil-mediated
-
anca-positive
- 3.4.21.20
- elastase
- neutrophil
- leukocyte
- proteinases
- granule
-
polymorphonuclear
- myeloperoxidase
- chymase
- granulocyte
- thrombin
- platelet
-
mast
-
azurophilic
- serpins
- plasmin
- lactoferrin
- collagenase
-
neutrophil-derived
-
granzyme
- kallikrein
-
1-proteinase
-
degranulation
- tryptase
-
antineutrophil
-
1-antichymotrypsin
- eglin
- drug development
- nsp4
-
antiproteinases
-
2-macroglobulin
- fmlp
- hne
- alpha-chymotrypsin
-
wegener
-
chediak-higashi
-
antiprotease
-
elastolytic
- chymostatin
- slpi
-
elastase-like
-
p-anca
- procollagenase
- alpha1-proteinase
- pharmacology
-
pmn-derived
- elafin
-
1-antitrypsin
- medicine
-
granulomatosis
- alpha1-antichymotrypsin
-
anti-cathepsin
-
neutrophil-mediated
-
anca-positive
Reaction
specificity similar to chymotrypsin C =
Synonyms
alpha-protease, cat G, Cat-G, Cat.G, CatG, Cath G, cathepsin G, chymotrypsin-like proteinase, CTSG, More, neutral proteinase, serine protease cathepsin G, Vimentin-specific protease, VSP
ECTree
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KM Value
KM Value on EC 3.4.21.20 - cathepsin G
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0.0097
7-methoxycoumarin-4-yl-acetyl-Phe-Val-Thr-(4-guanidine-L-phenylalanyl)-amino benzoyl-NH2
-
pH 7.5, 25°C
0.0099
7-methoxycoumarin-4-yl-acetyl-Phe-Val-Thr-(4-guanidine-L-phenylalanyl)-Ser-amino benzoyl-NH2
-
pH 7.5, 25°C
0.0035
7-methoxycoumarin-4-yl-acetyl-Phe-Val-Thr-(4-guanidine-L-phenylalanyl)-Ser-Asp-amino benzoyl-NH2
-
pH 7.5, 25°C
0.0032
7-methoxycoumarin-4-yl-acetyl-Phe-Val-Thr-(4-guanidine-L-phenylalanyl)-Ser-Phe-amino benzoyl-NH2
-
pH 7.5, 25°C
0.0021
7-methoxycoumarin-4-yl-acetyl-Phe-Val-Thr-(4-guanidine-L-phenylalanyl)-Ser-Trp-amino benzoyl-NH2
-
pH 7.5, 25°C
0.203
acetyl-Phe-Val-Thr-(4-guanidine-L-phenylalanyl)-amino benzoyl-NH2
-
pH 7.5, 25°C
0.12
-
wild type enzyme, in 1.8 M NaCl, pH 8.0, 37°C
0.2
N-succinyl-L-Val-L-Pro-L-Phe-4-nitroanilide
-
wild type enzyme, in PBS buffer, pH 8.0, 37°C
0.37
N-succinyl-L-Val-L-Pro-L-Phe-4-nitroanilide
-
mutant enzyme S189A/A226E, in PBS buffer, pH 8.0, 37°C
0.63
N-succinyl-L-Val-L-Pro-L-Phe-4-nitroanilide
-
mutant enzyme A226E, in PBS buffer, pH 8.0, 37°C
0.69
N-succinyl-L-Val-L-Pro-L-Phe-4-nitroanilide
-
wild type enzyme, in PBS buffer, pH 8.0, 37°C
1.73
N-succinyl-L-Val-L-Pro-L-Phe-4-nitroanilide
-
wild type enzyme, in 1.8 M NaCl, pH 8.0, 37°C
1.88
N-succinyl-L-Val-L-Pro-L-Phe-4-nitroanilide
-
mutant enzyme S189A/A226E, in 1.8 M NaCl, pH 8.0, 37°C
3.1
N-succinyl-L-Val-L-Pro-L-Phe-4-nitroanilide
-
mutant enzyme A226E, in 1.8 M NaCl, pH 8.0, 37°C