3.4.21.20: cathepsin G
This is an abbreviated version!
For detailed information about cathepsin G, go to the full flat file.
Word Map on EC 3.4.21.20
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3.4.21.20
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elastase
-
neutrophil
-
leukocyte
-
proteinases
-
granule
-
polymorphonuclear
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myeloperoxidase
-
chymase
-
granulocyte
-
thrombin
-
platelet
-
mast
-
azurophilic
-
serpins
-
plasmin
-
lactoferrin
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collagenase
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neutrophil-derived
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granzyme
-
kallikrein
-
1-proteinase
-
degranulation
-
tryptase
-
antineutrophil
-
1-antichymotrypsin
-
eglin
-
drug development
-
nsp4
-
antiproteinases
-
2-macroglobulin
-
fmlp
-
hne
-
alpha-chymotrypsin
-
wegener
-
chediak-higashi
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antiprotease
-
elastolytic
-
chymostatin
-
slpi
-
elastase-like
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p-anca
-
procollagenase
-
alpha1-proteinase
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pharmacology
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pmn-derived
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elafin
-
1-antitrypsin
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medicine
-
granulomatosis
-
alpha1-antichymotrypsin
-
anti-cathepsin
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neutrophil-mediated
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anca-positive
- 3.4.21.20
- elastase
- neutrophil
- leukocyte
- proteinases
- granule
-
polymorphonuclear
- myeloperoxidase
- chymase
- granulocyte
- thrombin
- platelet
-
mast
-
azurophilic
- serpins
- plasmin
- lactoferrin
- collagenase
-
neutrophil-derived
-
granzyme
- kallikrein
-
1-proteinase
-
degranulation
- tryptase
-
antineutrophil
-
1-antichymotrypsin
- eglin
- drug development
- nsp4
-
antiproteinases
-
2-macroglobulin
- fmlp
- hne
- alpha-chymotrypsin
-
wegener
-
chediak-higashi
-
antiprotease
-
elastolytic
- chymostatin
- slpi
-
elastase-like
-
p-anca
- procollagenase
- alpha1-proteinase
- pharmacology
-
pmn-derived
- elafin
-
1-antitrypsin
- medicine
-
granulomatosis
- alpha1-antichymotrypsin
-
anti-cathepsin
-
neutrophil-mediated
-
anca-positive
Reaction
specificity similar to chymotrypsin C =
Synonyms
alpha-protease, cat G, Cat-G, Cat.G, CatG, Cath G, cathepsin G, chymotrypsin-like proteinase, CTSG, More, neutral proteinase, serine protease cathepsin G, Vimentin-specific protease, VSP
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Expression
Expression on EC 3.4.21.20 - cathepsin G
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both CatG activity and transcript level are elevated in peripheral blood mononuclear cells from type 1 diabetes mellitus patients. Vitamin D reduces CatG activity only in myeloid dendritic cells from healthy donors
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level of cathepsin G is reduced in peripheral polymorphonuclear leukocytes of hemodialysis patients, while the mRNA enzyme level is not different
patients with atherosclerosis have significantly reduced plasma enzyme levels
the enzyme expression and activity is increased in peripheral blood mononuclear cells and muscle tissues of dermatomyositis patients
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patients with atherosclerosis have significantly reduced plasma enzyme levels