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3.4.21.1: chymotrypsin

This is an abbreviated version!
For detailed information about chymotrypsin, go to the full flat file.

Word Map on EC 3.4.21.1

Reaction

Preferential cleavage: Tyr-/-, Trp-/-, Phe-/-, Leu-/- =

Synonyms

4CHA, Alcalase, alpha chymar, alpha chymotrypsin, alpha-Chy, alpha-chymar ophth, alpha-chymotrypsin, alpha-chymotrypsin A, alpha-CT, avazyme, bovine alpha-chymotrypsin, caldecrin, cationic chymotrypsin, cellulomonadin, CHT, Chtp, Chtr1, Chtr2, Chtr3, Chtr4, ChTRP, CHY1, CHY20, chymar, chymotest, chymotrypsin, chymotrypsin A, chymotrypsin B, chymotrypsin C, chymotrypsin C1, chymotrypsin I, chymotrypsin II, chymotrypsin isoform Kh1, chymotrypsin isoform Kh2, chymotrypsin isoform Kh3, chymotrypsin-B, CTRA, Ctrb, EC 3.4.4.5, EC 3.4.4.6, enzeon, LBCP, lysosomal Bid cleavage protease, PEG-alpha-chymotrypsin, PEG-modified alpha-chymotrypsin, quimar, quimotrase, serine protease

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.1 chymotrypsin

pH Stability

pH Stability on EC 3.4.21.1 - chymotrypsin

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pH STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
1 - 2
-
the enzyme retains up to 80% of activity after 1 h of incubation at pH 3.0, 5.0, and 12.0
754581
2
-
5°C, about 55% loss of activity after 60 min
171870
4 - 8
-
60 min, less than 20% loss of activity
753641
5
-
the enzyme retains up to 80% of activity after 1 h of incubation at pH 3.0, 5.0, and 12.0
754581
5 - 10
120 min, no loss of activity
731855
5 - 12
-
5°C, stable for 60 min
171870
5 - 8
-
high stability at pH 7-8, unstable below pH 5
679953
6 - 11
7.4
-
25°C, stable for at least 10 h
171873
8
-
the enzyme conserves 100 % of its activity after 1 h
754581
additional information