Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
2-oxoimidazolidinyl-4-carbonyl-Gly-Ile + H2O
?
-
-
-
-
?
4(R)-N-(2-nitroxyethyl)-2-oxothiazolidine-4-carboxamide + H2O
L-2-oxothiazolidine-4-carboxylic acid + ?
5-pyrrolidone-2-carboxyl-His-Gly + H2O
?
-
slight activity
-
-
?
5-pyrrolidone-2-carboxyl-His-Trp + H2O
?
-
-
-
-
?
ACE inhibitor + H2O
pyroglutamate + ?
contains the N-terminal dipeptide pyroglutamyl-Trp-
-
?
acid-thyroliberin + H2O
pyroglutamate + His-Pro
bombesin + H2O
pyroglutamate + ?
contains the N-terminal dipeptide pyroglutamyl-Arg-
-
?
bombesin + H2O
pyroglutamate + Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2
bradykinin potentiator + H2O
pyroglutamate + ?
bradykinin potentiator B + H2O
pyroglutamate + ?
contains the N-terminal dipeptide pyroglutamyl-Gly-
-
?
bradykinin-potentiating peptide B + H2O
?
-
cleavage of the peptide bond adjacent to the pyroglutamic residue
-
-
?
ethyl L-pyroglutamate + H2O
L-pyroglutamate + ethanol
Fibrinogen + H2O
?
-
bovine fribrinogen
-
-
?
Glu(OMe)2-litorin + H2O
pyroglutamate + ?
-
-
-
?
gonadotropin-releasing hormone + H2O
?
hydrolyzed exclusively at the pyroglutamyl-/-Xaa bond
-
-
?
L-2-oxoimidazolidine-4-carboxyl-L-Ala + H2O
?
L-2-oxooxazolidine-4-carboxyl-aminoethylnitrate + H2O
?
-
-
-
-
?
L-2-oxooxazolidine-4-carboxyl-L-Ala + H2O
?
L-2-oxothiazolidine-4-carboxyl-D-2-aminopropylnitrate + H2O
?
-
-
-
-
?
L-2-oxothiazolidine-4-carboxyl-ethanolamine + H2O
?
-
-
-
-
?
L-2-oxothiazolidine-4-carboxyl-L-2-aminopropylnitrate + H2O
?
-
-
-
-
?
L-2-oxothiazolidine-4-carboxyl-L-Ala + H2O
?
L-pyroglutamic acid 2-naphthylamide + H2O
L-pyroglutamate + 2-naphthylamine
-
-
-
-
?
L-pyroglutamyl p-nitroanilide + H2O
L-pyroglutamate + p-nitroaniline
-
-
-
-
?
L-pyroglutamyl-7-amido-4-methylcoumarin + H2O
L-pyroglutamate + 7-amino-4-methylcoumarin
-
-
-
?
L-pyroglutamyl-aminoethylnitrate + H2O
?
-
-
-
-
?
L-pyroglutamyl-beta-naphthylamide + H2O
L-pyroglutamate + 2-naphthylamine
L-pyroglutamyl-beta-naphthylamide + H2O
L-pyroglutamate + 2-naphtylamine
-
-
-
-
?
L-pyroglutamyl-beta-naphthylamide + H2O
L-pyroglutamate + beta-naphthylamine
L-pyroglutamyl-beta-naphthylamide + H2O
L-pyroglutamate + beta-naphtylamine
-
-
-
-
?
L-pyroglutamyl-His-Pro-4-methylcoumarin 7-amide + H2O
L-pyroglutamate + His-Pro-4-methylcoumarin 7-amide
-
-
-
-
?
L-pyroglutamyl-L-Ala + H2O
L-pyroglutamate + L-Ala
L-pyroglutamyl-L-Ile + H2O
L-pyroglutamate + L-Ile
-
-
-
-
?
L-pyroglutamyl-L-Thr + H2O
L-pyroglutamate + L-Thr
-
-
-
-
?
L-pyroglutamyl-p-nitroanilide + H2O
L-pyroglutamate + p-nitroaniline
L-pyroglutamyl-p-nitroanilide + H2O
L-pyroglutaminic acid + p-nitroaniline
-
-
-
?
L-pyrrolidonyl 2-naphthylamide + H2O
5-oxo-L-proline + 2-naphthylamine
-
-
-
-
?
leukopyrokinin + H2O
pyroglutamate + ?
contains the N-terminal dipeptide pyroglutamyl-Thr-
-
?
litorin + H2O
pyroglutamate + Gln-Trp-Ala-Val-Gly-His-Phe-Met-NH2
luliberin + H2O
pyroglutamate + His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
luteinizing hormone releasing hormone + H2O
pyroglutamate + ?
contains the N-terminal dipeptide pyroglutamyl-His-
-
?
luteinizing-hormone-releasing hormone + H2O
?
N-(4-methyl-2-oxo-2H-chromen-7-yl)-5-oxo-L-prolinamide + H2O
5-oxo-L-proline + 7-amino-4-methylcoumarin
-
-
-
-
?
neurotensin + H2O
pyroglutamate + ?
contains the N-terminal dipeptide pyroglutamyl-Leu-
-
?
neurotensin + H2O
pyroglutamate + Leu-Tyr-Glu-Asn-Lys-Pro-Ag-Arg-Pro-Tyr-Ile-Leu
physalaemin + H2O
pyroglutamate + Ala-Asp-Pro-Asn-Lys-Phe-Tyr-Gly-Leu-Met-NH2
pyroglutamic acid-7-amido-4-methylcoumarin + H2O
L-pyroglutamate + 7-amino-4-methylcoumarin
-
-
-
-
?
pyroglutamyl-2-naphthylamide + H2O
pyroglutamate + 2-naphthylamine
-
-
-
-
?
pyroglutamyl-4-methylcoumarin 7-amide + H2O
pyroglutamate + 7-amino-4-methylcoumarin
pyroglutamyl-4-methylcoumaryl-7-amide + H2O
pyroglutamate + 7-amino-4-methylcoumarin
-
-
?
pyroglutamyl-4-methylumbelliferyl ester + H2O
?
-
-
-
-
?
pyroglutamyl-Ala + H2O
pyroglutamate + Ala
pyroglutamyl-Arg + H2O
pyroglutamate + Arg
-
-
-
-
?
pyroglutamyl-Asp + H2O
pyroglutamate + Asp
-
-
-
-
?
pyroglutamyl-beta-naphthylamide + H2O
pyroglutamate + beta-naphthylamine
pyroglutamyl-D-Ala + H2O
pyroglutamate + D-Ala
pyroglutamyl-D-Leu + H2O
pyroglutamate + D-Leu
-
-
-
-
?
pyroglutamyl-Glu + H2O
pyroglutamate + Glu
-
-
-
-
?
pyroglutamyl-Gly + H2O
pyroglutamate + Gly
-
-
-
-
?
pyroglutamyl-Gly-Ile + H2O
pyroglutamate + Gly-Ile
-
-
-
-
?
pyroglutamyl-His + H2O
pyroglutamate + His
-
-
-
-
?
pyroglutamyl-His-Gly + H2O
pyroglutamate + His-Gly
pyroglutamyl-His-Gly-NH2 + H2O
pyroglutamate + His-Gly-NH2
pyroglutamyl-His-Pro-Gly + H2O
pyroglutamate + His-Pro-Gly
-
-
-
-
?
pyroglutamyl-His-Pro-Gly-NH2 + H2O
pyroglutamate + His-Pro-Gly-NH2
-
-
-
-
?
pyroglutamyl-Ile + H2O
pyroglutamate + Ile
-
-
-
-
?
pyroglutamyl-Leu + H2O
pyroglutamate + Leu
-
-
-
-
?
pyroglutamyl-Lys + H2O
pyroglutamate + Lys
-
-
-
-
?
pyroglutamyl-Met + H2O
pyroglutamate + Met
-
-
-
-
?
pyroglutamyl-p-nitroanilide + H2O
pyroglutamate + p-nitroaniline
pyroglutamyl-peptide + H2O
pyroglutamate + peptide
-
the enzyme is able to specifically remove the amino-terminal pyroglutamyl residue protecting proteins or peptides from aminopeptidases
-
?
pyroglutamyl-Phe + H2O
pyroglutamate + Phe
-
-
-
-
?
pyroglutamyl-Phe-Pro-NH2 + H2O
pyroglutamate + Phe-Pro-NH2
-
-
-
-
?
pyroglutamyl-Ser + H2O
pyroglutamate + Ser
-
-
-
-
?
pyroglutamyl-Thr + H2O
pyroglutamate + Thr
-
-
-
-
?
pyroglutamyl-Trp + H2O
pyroglutamate + Trp
-
-
-
-
?
pyroglutamyl-Tyr + H2O
pyroglutamate + Tyr
-
-
-
-
?
pyroglutamyl-Val + H2O
pyroglutamate + Val
-
-
-
-
?
thyroliberin + H2O
pyroglutamate + His-Pro-NH2
thyroliberin-releasing hormone + H2O
?
-
-
-
-
?
thyrotrophin releasing hormone
?
thyrotrophin-releasing hormone + H2O
?
thyrotropin-releasing hormone + H2O
?
additional information
?
-
4(R)-N-(2-nitroxyethyl)-2-oxothiazolidine-4-carboxamide + H2O
L-2-oxothiazolidine-4-carboxylic acid + ?
-
-
-
-
?
4(R)-N-(2-nitroxyethyl)-2-oxothiazolidine-4-carboxamide + H2O
L-2-oxothiazolidine-4-carboxylic acid + ?
-
-
-
-
?
4(R)-N-(2-nitroxyethyl)-2-oxothiazolidine-4-carboxamide + H2O
L-2-oxothiazolidine-4-carboxylic acid + ?
-
-
-
-
?
acid-thyroliberin + H2O
pyroglutamate + His-Pro
-
-
-
-
?
acid-thyroliberin + H2O
pyroglutamate + His-Pro
-
i.e. pyroglutamyl-His-Pro
-
?
bombesin + H2O
pyroglutamate + Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2
-
-
-
-
?
bombesin + H2O
pyroglutamate + Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2
-
i.e. pyroglutamyl-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2
-
?
bradykinin potentiator + H2O
pyroglutamate + ?
-
-
-
-
?
bradykinin potentiator + H2O
pyroglutamate + ?
-
-
-
?
ethyl L-pyroglutamate + H2O
L-pyroglutamate + ethanol
-
-
-
?
ethyl L-pyroglutamate + H2O
L-pyroglutamate + ethanol
-
-
-
?
L-2-oxoimidazolidine-4-carboxyl-L-Ala + H2O
?
-
-
-
-
?
L-2-oxoimidazolidine-4-carboxyl-L-Ala + H2O
?
-
-
-
-
?
L-2-oxoimidazolidine-4-carboxyl-L-Ala + H2O
?
-
-
-
-
?
L-2-oxooxazolidine-4-carboxyl-L-Ala + H2O
?
-
-
-
-
?
L-2-oxooxazolidine-4-carboxyl-L-Ala + H2O
?
-
-
-
-
?
L-2-oxooxazolidine-4-carboxyl-L-Ala + H2O
?
-
-
-
-
?
L-2-oxothiazolidine-4-carboxyl-L-Ala + H2O
?
-
-
-
-
?
L-2-oxothiazolidine-4-carboxyl-L-Ala + H2O
?
-
-
-
-
?
L-2-oxothiazolidine-4-carboxyl-L-Ala + H2O
?
-
-
-
-
?
L-pyroglutamyl-beta-naphthylamide + H2O
L-pyroglutamate + 2-naphthylamine
-
-
-
?
L-pyroglutamyl-beta-naphthylamide + H2O
L-pyroglutamate + 2-naphthylamine
-
-
-
?
L-pyroglutamyl-beta-naphthylamide + H2O
L-pyroglutamate + beta-naphthylamine
-
-
-
?
L-pyroglutamyl-beta-naphthylamide + H2O
L-pyroglutamate + beta-naphthylamine
-
-
-
?
L-pyroglutamyl-beta-naphthylamide + H2O
L-pyroglutamate + beta-naphthylamine
-
-
-
?
L-pyroglutamyl-beta-naphthylamide + H2O
L-pyroglutamate + beta-naphthylamine
-
-
-
?
L-pyroglutamyl-beta-naphthylamide + H2O
L-pyroglutamate + beta-naphthylamine
-
-
-
?
L-pyroglutamyl-L-Ala + H2O
L-pyroglutamate + L-Ala
-
-
-
-
?
L-pyroglutamyl-L-Ala + H2O
L-pyroglutamate + L-Ala
-
-
-
-
?
L-pyroglutamyl-L-Ala + H2O
L-pyroglutamate + L-Ala
-
-
-
-
?
L-pyroglutamyl-L-Ala + H2O
L-pyroglutamate + L-Ala
-
-
-
-
?
L-pyroglutamyl-p-nitroanilide + H2O
L-pyroglutamate + p-nitroaniline
-
-
-
?
L-pyroglutamyl-p-nitroanilide + H2O
L-pyroglutamate + p-nitroaniline
-
-
-
-
?
L-pyroglutamyl-p-nitroanilide + H2O
L-pyroglutamate + p-nitroaniline
-
-
-
?
L-pyroglutamyl-p-nitroanilide + H2O
L-pyroglutamate + p-nitroaniline
-
-
-
?
L-pyroglutamyl-p-nitroanilide + H2O
L-pyroglutamate + p-nitroaniline
-
-
-
?
litorin + H2O
pyroglutamate + Gln-Trp-Ala-Val-Gly-His-Phe-Met-NH2
-
frog litorin
-
?
litorin + H2O
pyroglutamate + Gln-Trp-Ala-Val-Gly-His-Phe-Met-NH2
-
frog litorin
-
?
luliberin + H2O
pyroglutamate + His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
-
i.e. pyroglutamyl-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
-
?
luliberin + H2O
pyroglutamate + His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
-
-
-
-
?
luteinizing-hormone-releasing hormone + H2O
?
-
-
-
-
?
luteinizing-hormone-releasing hormone + H2O
?
-
-
-
-
?
luteinizing-hormone-releasing hormone + H2O
?
-
-
-
-
?
neurotensin + H2O
pyroglutamate + Leu-Tyr-Glu-Asn-Lys-Pro-Ag-Arg-Pro-Tyr-Ile-Leu
-
-
-
-
?
neurotensin + H2O
pyroglutamate + Leu-Tyr-Glu-Asn-Lys-Pro-Ag-Arg-Pro-Tyr-Ile-Leu
-
-
-
-
?
neurotensin + H2O
pyroglutamate + Leu-Tyr-Glu-Asn-Lys-Pro-Ag-Arg-Pro-Tyr-Ile-Leu
-
i.e. pyroglutamyl-Leu-Tyr-Glu-Asn-Lys-Pro-Ag-Arg-Pro-Tyr-Ile-Leu
-
?
neurotensin + H2O
pyroglutamate + Leu-Tyr-Glu-Asn-Lys-Pro-Ag-Arg-Pro-Tyr-Ile-Leu
-
-
-
-
?
neurotensin + H2O
pyroglutamate + Leu-Tyr-Glu-Asn-Lys-Pro-Ag-Arg-Pro-Tyr-Ile-Leu
-
-
-
-
?
physalaemin + H2O
pyroglutamate + Ala-Asp-Pro-Asn-Lys-Phe-Tyr-Gly-Leu-Met-NH2
-
-
-
?
physalaemin + H2O
pyroglutamate + Ala-Asp-Pro-Asn-Lys-Phe-Tyr-Gly-Leu-Met-NH2
-
-
-
?
pyroglutamyl-4-methylcoumarin 7-amide + H2O
pyroglutamate + 7-amino-4-methylcoumarin
-
-
-
-
?
pyroglutamyl-4-methylcoumarin 7-amide + H2O
pyroglutamate + 7-amino-4-methylcoumarin
-
-
-
-
?
pyroglutamyl-4-methylcoumarin 7-amide + H2O
pyroglutamate + 7-amino-4-methylcoumarin
-
-
-
-
?
pyroglutamyl-Ala + H2O
pyroglutamate + Ala
-
-
-
-
?
pyroglutamyl-Ala + H2O
pyroglutamate + Ala
-
-
-
-
?
pyroglutamyl-Ala + H2O
pyroglutamate + Ala
-
-
-
-
?
pyroglutamyl-beta-naphthylamide + H2O
pyroglutamate + beta-naphthylamine
-
-
-
-
?
pyroglutamyl-beta-naphthylamide + H2O
pyroglutamate + beta-naphthylamine
-
-
-
-
?
pyroglutamyl-beta-naphthylamide + H2O
pyroglutamate + beta-naphthylamine
-
-
-
-
?
pyroglutamyl-beta-naphthylamide + H2O
pyroglutamate + beta-naphthylamine
-
-
-
-
?
pyroglutamyl-beta-naphthylamide + H2O
pyroglutamate + beta-naphthylamine
-
-
-
-
?
pyroglutamyl-beta-naphthylamide + H2O
pyroglutamate + beta-naphthylamine
no activity in Staphylococcus aureus
-
-
-
-
?
pyroglutamyl-beta-naphthylamide + H2O
pyroglutamate + beta-naphthylamine
no activity in Staphylococcus aureus ATCC 25923
-
-
-
-
?
pyroglutamyl-beta-naphthylamide + H2O
pyroglutamate + beta-naphthylamine
no activity in Staphylococcus pseudintermedius
-
-
-
-
?
pyroglutamyl-beta-naphthylamide + H2O
pyroglutamate + beta-naphthylamine
no activity in Staphylococcus pseudintermedius LMG 22219T
-
-
-
-
?
pyroglutamyl-beta-naphthylamide + H2O
pyroglutamate + beta-naphthylamine
-
-
-
-
?
pyroglutamyl-beta-naphthylamide + H2O
pyroglutamate + beta-naphthylamine
-
-
-
-
?
pyroglutamyl-beta-naphthylamide + H2O
pyroglutamate + beta-naphthylamine
-
-
-
-
?
pyroglutamyl-beta-naphthylamide + H2O
pyroglutamate + beta-naphthylamine
-
-
-
-
?
pyroglutamyl-beta-naphthylamide + H2O
pyroglutamate + beta-naphthylamine
-
-
-
-
?
pyroglutamyl-beta-naphthylamide + H2O
pyroglutamate + beta-naphthylamine
-
-
-
-
?
pyroglutamyl-beta-naphthylamide + H2O
pyroglutamate + beta-naphthylamine
-
-
-
-
?
pyroglutamyl-beta-naphthylamide + H2O
pyroglutamate + beta-naphthylamine
-
-
-
-
?
pyroglutamyl-beta-naphthylamide + H2O
pyroglutamate + beta-naphthylamine
-
-
-
-
?
pyroglutamyl-beta-naphthylamide + H2O
pyroglutamate + beta-naphthylamine
-
-
-
-
?
pyroglutamyl-beta-naphthylamide + H2O
pyroglutamate + beta-naphthylamine
-
-
-
-
?
pyroglutamyl-beta-naphthylamide + H2O
pyroglutamate + beta-naphthylamine
-
-
-
-
?
pyroglutamyl-beta-naphthylamide + H2O
pyroglutamate + beta-naphthylamine
-
-
-
-
?
pyroglutamyl-beta-naphthylamide + H2O
pyroglutamate + beta-naphthylamine
-
-
-
-
?
pyroglutamyl-beta-naphthylamide + H2O
pyroglutamate + beta-naphthylamine
-
-
-
-
?
pyroglutamyl-beta-naphthylamide + H2O
pyroglutamate + beta-naphthylamine
-
-
-
-
?
pyroglutamyl-D-Ala + H2O
pyroglutamate + D-Ala
-
-
-
-
?
pyroglutamyl-D-Ala + H2O
pyroglutamate + D-Ala
-
slight activity
-
-
?
pyroglutamyl-His-Gly + H2O
pyroglutamate + His-Gly
-
-
-
-
?
pyroglutamyl-His-Gly + H2O
pyroglutamate + His-Gly
-
-
-
-
?
pyroglutamyl-His-Gly + H2O
pyroglutamate + His-Gly
-
i.e. anorexogenic peptide
-
?
pyroglutamyl-His-Gly-NH2 + H2O
pyroglutamate + His-Gly-NH2
-
-
-
-
?
pyroglutamyl-His-Gly-NH2 + H2O
pyroglutamate + His-Gly-NH2
-
-
-
-
?
pyroglutamyl-p-nitroanilide + H2O
pyroglutamate + p-nitroaniline
-
-
-
-
?
pyroglutamyl-p-nitroanilide + H2O
pyroglutamate + p-nitroaniline
-
-
-
-
?
thyroliberin + H2O
pyroglutamate + His-Pro-NH2
-
-
-
-
?
thyroliberin + H2O
pyroglutamate + His-Pro-NH2
-
-
-
-
?
thyroliberin + H2O
pyroglutamate + His-Pro-NH2
-
removes the N-terminal pyroglutamic acid
-
-
?
thyroliberin + H2O
pyroglutamate + His-Pro-NH2
-
i.e. pyroglutamyl-His-Pro-NH2, i.e. thyrotrophin releasing hormone
-
?
thyroliberin + H2O
pyroglutamate + His-Pro-NH2
-
-
-
-
?
thyroliberin + H2O
pyroglutamate + His-Pro-NH2
-
-
-
-
?
thyroliberin + H2O
pyroglutamate + His-Pro-NH2
-
-
-
?
thyroliberin + H2O
pyroglutamate + His-Pro-NH2
-
-
-
-
?
thyrotrophin releasing hormone
?
-
the enzyme is proposed to inactivate thyrotrophin releasing hormone in brain extracellular space
-
-
?
thyrotrophin releasing hormone
?
-
-
-
-
?
thyrotrophin-releasing hormone + H2O
?
trypanosomal pyroglutamyl aminopeptidase I is responsible for the abnormally rapid degradation of thyrotrophin-releasing hormone in the circulation of infected rats
-
-
?
thyrotrophin-releasing hormone + H2O
?
hydrolyzed exclusively at the pyroglutamyl-/-Xaa bond
-
-
?
thyrotropin-releasing hormone + H2O
?
-
-
-
?
thyrotropin-releasing hormone + H2O
?
-
-
-
?
thyrotropin-releasing hormone + H2O
?
-
-
-
-
?
thyrotropin-releasing hormone + H2O
?
-
-
-
?
additional information
?
-
-
slight activity toward L-pyroglutamyl-D-amino acids, inert toward L-pyroglutamyl-L-Pro
-
-
?
additional information
?
-
-
the molecular recognition of pyroglutamic acid is achieved through two hydrogen bonds and an insertion in the hydrophobic pocket. In the pocket Phe10 is more important to the hydrophobic interaction than is Phe142 and furthermore Phe13 serves as an induced fit mechanism
-
?
additional information
?
-
-
the enzyme does not catalyze the hydrolysis of peptides with six-membered ureido rings at the amino terminus, but it tolerates well a five-membered ureido ring at this position
-
-
?
additional information
?
-
-
the enzyme appears to play an important role in the activation and inactivation of many N-terminal pyroglutamyl-terminating peptides
-
-
?
additional information
?
-
-
no hydrolysis of dipeptides containing N-terminal pyroglutamic acid or with pyroglutamyl peptides containing more than three amino acids
-
-
?
additional information
?
-
-
the enzyme appears to play an important role in the activation and inactivation of many N-terminal pyroglutamyl-terminating peptides
-
-
?
additional information
?
-
-
the enzyme appears to play an important role in the activation and inactivation of many N-terminal pyroglutamyl-terminating peptides
-
-
?
additional information
?
-
-
the enzyme appears to play an important role in the activation and inactivation of many N-terminal pyroglutamyl-terminating peptides
-
-
?
additional information
?
-
-
the enzyme is inactive towards uperolein and piperidone carbonyl His-Pro-NH2
-
-
?
additional information
?
-
-
the enzyme appears to play an important role in the activation and inactivation of many N-terminal pyroglutamyl-terminating peptides
-
-
?
additional information
?
-
-
enzyme may participate in regulating the levels of seminal thyrotropin-relasing hormone analogues and in mediating sperm death associated with necrozoospermia
-
-
?
additional information
?
-
-
the enzyme appears to play an important role in the activation and inactivation of many N-terminal pyroglutamyl-terminating peptides
-
-
?
additional information
?
-
-
-
-
-
?
additional information
?
-
-
pyroglutamate and iron regulate the expression of the enzyme
-
-
?
additional information
?
-
-
pyroglutamate and iron regulate the expression of the enzyme
-
-
?
additional information
?
-
-
PGAP performs enzymatic deblocking of pyroglutamylated immunoglobulins. Unfolding of immunoglobulins is required for excision of the pyroglutamate. The enzyme requires the substrate in an extended conformation, which is not fullfiled in the native form of immunoglobulins
-
-
?
additional information
?
-
-
the enzyme appears to play an important role in the activation and inactivation of many N-terminal pyroglutamyl-terminating peptides
-
-
?
additional information
?
-
-
diurnal variation and left-right distribution of pyroglutamyl peptidase I activity in the rat brain and retina
-
-
?
additional information
?
-
-
pyroglutamyl peptidase I levels and their left-right distribution in the rat retina and hypothalamus are influenced by light-dark conditions
-
-
?
additional information
?
-
the enzyme might not be dominantly involved in the degradation of thyrotropin-releasing hormone in rats
-
-
?
additional information
?
-
-
the enzyme appears to play an important role in the activation and inactivation of many N-terminal pyroglutamyl-terminating peptides
-
-
?
additional information
?
-
-
the enzyme appears to play an important role in the activation and inactivation of many N-terminal pyroglutamyl-terminating peptides
-
-
?