3.4.18.1: cathepsin X

This is an abbreviated version!
For detailed information about cathepsin X, go to the full flat file.

Word Map on EC 3.4.18.1

Reaction

Release of C-terminal amino acid residues with broad specificity, but lacks action on C-terminal proline. Shows weak endopeptidase activity =

Synonyms

cathepsin B2, cathepsin IV, acid carboxypeptidase, lysosomal carboxypeptidase B, cathepsin Z, cysteine-type carboxypeptidase, cathepsin X, CATX, CTPZ, CTSZ, PoCtX, CTSX, mopre, cathepsin P

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.18 Cysteine-type carboxypeptidases
                3.4.18.1 cathepsin X

KM Value

KM Value on EC 3.4.18.1 - cathepsin X

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0018
(2,4-dinitrophenyl)-GFFGW
-
pH 5.1, 37°C
0.0036
(2,4-dinitrophenyl)-GFFRW
-
pH 5.1, 37°C
0.001
(2,4-dinitrophenyl)-GFFW
-
pH 5.1, 37°C
0.0024
(2,4-dinitrophenyl)-GFRFW
-
pH 5.1, 37°C
0.0042
(2,4-dinitrophenyl)-GFRW
-
pH 5.1, 37°C
0.0046
(2,4-dinitrophenyl)-GRFFW
-
pH 5.1, 37°C
0.063
CBZ-FR-7-amido-4-methylcoumarin
-
pH 5.1, 37°C
0.13
CBZ-RR-7-amido-4-methylcoumarin
-
pH 5.1, 37°C
0.5
glucagon
-
-
0.69
hippuryl-L-Arg
-
D253R mutant
0.0083
ortho-aminobenzoyl-Arg-Arg-(2,3-diaminopropionyl)-(2,4-dinitrophenyl)-Pro +
-
pH 5.1, 37°C
-
0.0105
ortho-aminobenzoyl-Lys-Arg-(2,3-diaminopropionyl)-(2,4-dinitrophenyl)-Pro
-
pH 5.1, 37°C
-
0.0037
ortho-aminobenzoyl-Phe-Arg-(2,3-diaminopropionyl)-(2,4-dinitrophenyl)-Pro
-
pH 5.1, 37°C
-