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3.4.17.20: Carboxypeptidase U

This is an abbreviated version!
For detailed information about Carboxypeptidase U, go to the full flat file.

Word Map on EC 3.4.17.20

Reaction

release of C-terminal Arg and Lys from a polypeptide =

Synonyms

aCAP, activated thrombin activable fibrinolysis inhibitor, activated thrombin-activable fibrinolysis inhibitor, activated thrombin-activatable fibrinolysis inhibitor, active carboxypeptidase B, active thrombin-activatable fibrinolysis inhibitor, Arginine carboxypeptidase, Carboxypeptidase B, pro-, carboxypeptidase B2, Carboxypeptidase R, carboxypeptidase U, Carboxypeptidase-U, CPB2, CPR, CPU, Plasma carboxypeptidase B, plasma carboxypeptidase U, plasma CPB, plasma procarboxypeptidase B, plasma procarboxypeptidase B-like proenzyme, plasma procarboxypeptidase U, pro-pCPB, Procarboxypeptidase B, procarboxypeptidase R, procarboxypeptidase U, proCPU, pTAFI, rTAFI, TAFI, TAFIa, TFAI, thrombin activable fibrinolysis inhibitor, thrombin activatable fibrinolysis inhibitor, Thrombin-activable fibrinolysis inhibitor, thrombin-activatable fibrinolysis inhibitor

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.17 Metallocarboxypeptidases
                3.4.17.20 Carboxypeptidase U

Turnover Number

Turnover Number on EC 3.4.17.20 - Carboxypeptidase U

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
15.9 - 29.5
anisylazoformyl-Lys
748
Arg6-Leu5-enkephalin
-
-
647
Arg6-Met5-enkephalin
-
-
2.3
biotinyl-(epsilon-aminocaproic acid)-(epsilon-aminocaproic acid)-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Arg-OH
-
room temperature
121
bradykinin
-
-
2.67 - 2.74
hippuryl-Arg
0.00004 - 0.00043
hippuryl-arginine
26 - 56.7
hippuryl-L-Arg
169
Hippuryl-L-argininic acid
-
-
15 - 45.6
Hippuryl-L-Lys
282
Lys6-Leu5-enkephalin
-
-
290
Lys6-Met5-enkephalin
-
-
59
N-benzoyl-2'-cyano-L-Phe-L-Arg
-
in 50 mM HEPES (pH 8.0) at 25°C
64
N-benzoyl-Gly-L-Arg
-
in 50 mM HEPES (pH 8.0) at 25°C
36
N-[3-(2-Furylacryloyl)]-L-Ala-L-Arg
-
-
29 - 293
N-[3-(2-Furylacryloyl)]-L-Ala-L-Lys
0.205 - 0.377
p-anisylazoformyl-L-arginine