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3.4.17.20: Carboxypeptidase U

This is an abbreviated version!
For detailed information about Carboxypeptidase U, go to the full flat file.

Word Map on EC 3.4.17.20

Reaction

release of C-terminal Arg and Lys from a polypeptide =

Synonyms

aCAP, activated thrombin activable fibrinolysis inhibitor, activated thrombin-activable fibrinolysis inhibitor, activated thrombin-activatable fibrinolysis inhibitor, active carboxypeptidase B, active thrombin-activatable fibrinolysis inhibitor, Arginine carboxypeptidase, Carboxypeptidase B, pro-, carboxypeptidase B2, Carboxypeptidase R, carboxypeptidase U, Carboxypeptidase-U, CPB2, CPR, CPU, Plasma carboxypeptidase B, plasma carboxypeptidase U, plasma CPB, plasma procarboxypeptidase B, plasma procarboxypeptidase B-like proenzyme, plasma procarboxypeptidase U, pro-pCPB, Procarboxypeptidase B, procarboxypeptidase R, procarboxypeptidase U, proCPU, pTAFI, rTAFI, TAFI, TAFIa, TFAI, thrombin activable fibrinolysis inhibitor, thrombin activatable fibrinolysis inhibitor, Thrombin-activable fibrinolysis inhibitor, thrombin-activatable fibrinolysis inhibitor

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.17 Metallocarboxypeptidases
                3.4.17.20 Carboxypeptidase U

KM Value

KM Value on EC 3.4.17.20 - Carboxypeptidase U

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.979 - 1.26
anisylazoformyl-Lys
63
Arg6-Leu5-enkephalin
-
-
140
Arg6-Met5-enkephalin
-
-
0.012
biotinyl-(epsilon-aminocaproic acid)-(epsilon-aminocaproic acid)-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Arg-OH
-
room temperature
10
bradykinin
-
-
2.38 - 3.44
hippuryl-Arg
0.000005 - 0.00001
hippuryl-arginine
1.12 - 817
hippuryl-L-Arg
240
Hippuryl-L-argininic acid
-
-
1.45 - 933
Hippuryl-L-Lys
110
Lys6-Leu5-enkephalin
-
-
220
Lys6-Met5-enkephalin
-
-
0.02
N-benzoyl-2'-cyano-L-Phe-L-Arg
-
in 50 mM HEPES (pH 8.0) at 25°C
0.84
N-benzoyl-Gly-L-Arg
-
in 50 mM HEPES (pH 8.0) at 25°C
210
N-[3-(2-Furylacryloyl)]-L-Ala-L-Arg
-
-
3.41 - 280
N-[3-(2-Furylacryloyl)]-L-Ala-L-Lys
0.000162 - 0.000232
p-anisylazoformyl-L-arginine
additional information
additional information
-
binding kinetics of recombinant wild-type and chimeric mutant isozymes to fibrinogen and plasminogen, overview
-