3.4.17.2: carboxypeptidase B

This is an abbreviated version!
For detailed information about carboxypeptidase B, go to the full flat file.

Word Map on EC 3.4.17.2

Reaction

preferential release of a C-terminal lysine or arginine amino acid =

Synonyms

More, TAFI, EC 3.4.2.2, EC 3.4.12.3, protaminase, carboxypeptidase BII, CPB, Cbp, 47 kDa zymogen granule membrane associated protein, Pancreas-specific protein, PASP, ZAP47, PCB, CPB1, thrombin-activatable fibrinolysis inhibitor, HBCPB, PcpB, aCAP, tissue carboxypeptidase B, basic carboxypeptidase, pp-CpB, B carboxypeptidase, CPBAg1, CPB2, carboxypeptidase B, thrombin-activatable procarboxypeptidase B, Carboxypeptidase B1, HzCPB, cpbAs1, ppCPB, carboxypeptidase B2

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.17 Metallocarboxypeptidases
                3.4.17.2 carboxypeptidase B

Source Tissue

Source Tissue on EC 3.4.17.2 - carboxypeptidase B

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
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majority of the enzyme exists in the prepro-form
Manually annotated by BRENDA team
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longitudinal, of instestine
Manually annotated by BRENDA team
-
in synovial fluids from osteoarthritis patients, high levels of proCPB are associated with high levels of proinflammatory cytokines and complement components, and levels of proCPB correlated positively with those of membrane attack complex (MAC)
Manually annotated by BRENDA team
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fibroblast-like synoviocytes
Manually annotated by BRENDA team