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3.4.17.2: carboxypeptidase B

This is an abbreviated version!
For detailed information about carboxypeptidase B, go to the full flat file.

Word Map on EC 3.4.17.2

Reaction

preferential release of a C-terminal lysine or arginine amino acid =

Synonyms

47 kDa zymogen granule membrane associated protein, aCAP, B carboxypeptidase, basic carboxypeptidase, carboxypeptidase B, Carboxypeptidase B1, carboxypeptidase B2, carboxypeptidase BII, Cbp, CPB, CPB1, CPB2, CPBAg1, cpbAs1, EC 3.4.12.3, EC 3.4.2.2, HBCPB, HzCPB, More, Pancreas-specific protein, PASP, PCB, PcpB, pp-CpB, ppCPB, protaminase, TAFI, thrombin-activatable fibrinolysis inhibitor, thrombin-activatable procarboxypeptidase B, tissue carboxypeptidase B, ZAP47

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.17 Metallocarboxypeptidases
                3.4.17.2 carboxypeptidase B

KM Value

KM Value on EC 3.4.17.2 - carboxypeptidase B

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.012
3-(2-furyl)acryloyl-L-Ala-L-Arg
-
-
0.1 - 8
benzoyl-Gly-Arg
24 - 40
benzoyl-Gly-Gly-Phe
3 - 80
benzoyl-Gly-glycylphenyllactic acid
0.32
benzoyl-Gly-L-Arg
-
-
0.008
biotin-(epsilon-aminocaproic acid)2-GLMVGGVVR
-
pH 7.4
80 - 100
Carbobenzoxy-Gly-Phe
0.1
furylacryloyl-L-alanyl-L-arginine
-
-
-
0.12
furylacryloylalanylarginine
-
-
0.07 - 0.11
furylacryloylalanyllysine
0.277 - 0.54
hippuryl-Arg
0.05 - 28
hippuryl-L-Arg
2.63 - 3.55
hippuryl-Lys
0.06
N-(4-methoxyphenylazoformyl)-Arg
0.6
N-(phenylcarbonyl)glycyl-L-arginine
-
crystallized enzyme
0.15
N-benzoylglycyl-L-Arg
-
carboxypeptidase B I and B II
additional information
additional information
-