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3.4.17.2: carboxypeptidase B

This is an abbreviated version!
For detailed information about carboxypeptidase B, go to the full flat file.

Word Map on EC 3.4.17.2

Reaction

preferential release of a C-terminal lysine or arginine amino acid =

Synonyms

47 kDa zymogen granule membrane associated protein, aCAP, B carboxypeptidase, basic carboxypeptidase, carboxypeptidase B, Carboxypeptidase B1, carboxypeptidase B2, carboxypeptidase BII, Cbp, CPB, CPB1, CPB2, CPBAg1, cpbAs1, EC 3.4.12.3, EC 3.4.2.2, HBCPB, HzCPB, More, Pancreas-specific protein, PASP, PCB, PcpB, pp-CpB, ppCPB, protaminase, TAFI, thrombin-activatable fibrinolysis inhibitor, thrombin-activatable procarboxypeptidase B, tissue carboxypeptidase B, ZAP47

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.17 Metallocarboxypeptidases
                3.4.17.2 carboxypeptidase B

Activating Compound

Activating Compound on EC 3.4.17.2 - carboxypeptidase B

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
allopurinol
-
addition of allopurinol alone and allopurinol plus 5,5-dimethyl-1-pyrroline N-oxide results in increased CPB1 activity
L-Cys
-
activates
thrombin
-
-
-
Thrombomodulin
-
HT1080 cells mediate activation of TAFI in plasma in the presence of soluble-type thrombomodulin through cell-dependent prothrombin activation. HT1080 cells stably expressing thrombomodulin mediate plasma TAFI activation without added soluble thrombomodulin
-
additional information
-
the enzyme expression in the midgut is affected by ingestion of Plasmodium falciparum
-