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3.4.16.2: lysosomal Pro-Xaa carboxypeptidase

This is an abbreviated version!
For detailed information about lysosomal Pro-Xaa carboxypeptidase, go to the full flat file.

Word Map on EC 3.4.16.2

Reaction

Cleavage of a -Pro-/-Xaa bond to release a C-terminal amino acid =

Synonyms

aminoacylproline carboxypeptidase, angiotensinase C, carboxypeptidase, carboxypeptidase A6, Carboxypeptidase P, Carboxypeptidase R, carboxypeptidase, aminoacylproline, carboxypeptidase, peptidylprolylamino acid, CPA6, CPP, EC 3.4.12.4, endothelial cell prekallikrein activator, HUVEC PK activator, lysosomal carboxypeptidase, lysosomal carboxypeptidase C, lysosomal Pro-X carboxypeptidase, matrix PK activator, PCP, PKA, plasma carboxypeptidase, plasma procarboxypeptidase B, PRCP, procarboxypeptidase U, proline carboxypeptidase, proline-specific carboxypeptidase P, prolyl carboxypeptidase, prolyl-carboxypeptidase, prolylcarboxypeptidase, serine protease prolylcarboxypeptidase, TAFI, thrombin-activatable fibrinolysis inhibitor

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.16 Serine-type carboxypeptidases
                3.4.16.2 lysosomal Pro-Xaa carboxypeptidase

Source Tissue

Source Tissue on EC 3.4.16.2 - lysosomal Pro-Xaa carboxypeptidase

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
aortic aneurysm and normal aorta
Manually annotated by BRENDA team
-
pancreatic cancer cell line
Manually annotated by BRENDA team
-
greatest level of signals are detected in the cerebral cortex with very strong labeling in the cingulate and piriform cortex. Other areas of the cortex show moderate signal intensity
Manually annotated by BRENDA team
-
embryonic tissue
Manually annotated by BRENDA team
-
used for transfection
Manually annotated by BRENDA team
-
within the limbic system, strong signal is detected in the hippocampus and in the amygdaloid complex
Manually annotated by BRENDA team
anterior midgut of larvae
Manually annotated by BRENDA team
-
RNA is extracted from leukocytes
Manually annotated by BRENDA team
-
-
Manually annotated by BRENDA team
expression of PRCP protein or kallikrein mRNA expression is significantly inhibited in the right kidneys and mesenteric arteries of hypertensive rats. Expression is significantly increased after treatment with rutaecarpine or lorsartan
Manually annotated by BRENDA team
-
enzyme mRNA detected in the zona incerta and the ventral tegmental area
Manually annotated by BRENDA team
-
pancreatic cancer cell line
Manually annotated by BRENDA team
-
prolylcarboxypeptidase transcript levels are compared
Manually annotated by BRENDA team
-
pancreatic cancer cell line
Manually annotated by BRENDA team
-
foreskin fibroblast
Manually annotated by BRENDA team
-
root of seedling
Manually annotated by BRENDA team
-
shoot of seedling
Manually annotated by BRENDA team
-
strong expression
Manually annotated by BRENDA team