3.4.14.2: dipeptidyl-peptidase II
This is an abbreviated version!
For detailed information about dipeptidyl-peptidase II, go to the full flat file.
Word Map on EC 3.4.14.2
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3.4.14.2
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glucagon-like
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glp-1
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mellitus
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dpp-iv
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incretins
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peptidase-4
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peptide-1
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lysosomal
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dipeptides
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antidiabetic
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glycemic
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cathepsins
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prolyl
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insulinotropic
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linagliptin
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vildagliptin
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metformin
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glucose-dependent
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glucagon
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postprandial
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iv-deficient
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hypoglycemia
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glucose-lowering
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exopeptidase
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gip
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sulfonylurea
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aminopeptidases
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iv-like
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antihyperglycemic
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repopulation
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3.4.14.5
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proline-specific
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oligopeptidase
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saxagliptin
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gelatinase
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incretin-based
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alogliptin
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thiazolidinediones
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liraglutide
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excursion
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gliptins
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sodium-glucose
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retrorsine
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exenatide
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post-proline
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diprotin
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tripeptidyl
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crevicular
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analysis
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medicine
- 3.4.14.2
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glucagon-like
- glp-1
- mellitus
- dpp-iv
- incretins
-
peptidase-4
- peptide-1
- lysosomal
- dipeptides
-
antidiabetic
-
glycemic
- cathepsins
-
prolyl
-
insulinotropic
- linagliptin
- vildagliptin
- metformin
-
glucose-dependent
- glucagon
-
postprandial
-
iv-deficient
- hypoglycemia
-
glucose-lowering
-
exopeptidase
- gip
- sulfonylurea
- aminopeptidases
-
iv-like
-
antihyperglycemic
-
repopulation
-
3.4.14.5
-
proline-specific
-
oligopeptidase
- saxagliptin
- gelatinase
-
incretin-based
- alogliptin
- thiazolidinediones
- liraglutide
-
excursion
-
gliptins
-
sodium-glucose
- retrorsine
-
exenatide
-
post-proline
- diprotin
-
tripeptidyl
-
crevicular
- analysis
- medicine
Reaction
release of an N-terminal dipeptide, Xaa-Yaa-/-, preferentially when Yaa is Ala or Pro. Substrates are oligopeptides, preferentially tripeptides =
Synonyms
brain dipeptidyl aminopeptidase A, carboxytripeptidase, dipeptidyl aminopeptidase II, dipeptidyl arylamidase II, dipeptidyl peptidase, dipeptidyl peptidase 2, dipeptidyl peptidase II, dipeptidyl-aminopeptidase II, dipeptidylpeptidase II, DP II, DPP, DPP II, DPP-II, DPP2, DPP7, DPPII, DPPV, fibroblast activation protein alpha, GPA, More, peptidase, dipeptidyl, II, QPP, quiescent cell proline dipeptidase, seprase
ECTree
3.4.14.2 dipeptidyl-peptidase IIAdvanced search results
results (
results (Natural Substrates Products
Natural Substrates Products on EC 3.4.14.2 - dipeptidyl-peptidase II
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
additional information
?
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the enzyme contributes to the alveolar macrophage's proteolytic capabilities
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-
?
additional information
?
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the enzyme contributes to the alveolar macrophage's proteolytic capabilities
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-
?
additional information
?
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hydrolyzes specifically N-terminal X-alanine or X-proline from their respective arylamides and from tripeptides or tetrapeptides, but not from pentapeptides
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-
?
additional information
?
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possible role of the mast cell enzyme in remodelling of connective tissue
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-
?
additional information
?
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the enzyme may play a role in the segregation and degradation of specific regions of normal lens fiber cells
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-
?
