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3.4.13.12: Met-Xaa dipeptidase

This is an abbreviated version!
For detailed information about Met-Xaa dipeptidase, go to the full flat file.

Reaction

Hydrolysis of Met-/-Xaa dipeptides. =

Synonyms

methionyl dipeptidase, dipeptidase M

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.13 Dipeptidases
                3.4.13.12 Met-Xaa dipeptidase

Substrates Products

Substrates Products on EC 3.4.13.12 - Met-Xaa dipeptidase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
Ala-Ala + H2O
Ala + Ala
show the reaction diagram
-
-
-
ir
Ala-Leu + H2O
Ala + Leu
show the reaction diagram
-
-
-
ir
Ala-Met + H2O
Ala + Met
show the reaction diagram
ethionyl-Ala + H2O
ethionine + Ala
show the reaction diagram
-
-
-
ir
Gly-Gly + H2O
Gly + Gly
show the reaction diagram
-
-
-
ir
Leu-Ala + H2O
Leu + Ala
show the reaction diagram
Met-Ala + H2O
Met + Ala
show the reaction diagram
Met-amino acid + H2O
?
show the reaction diagram
Met-Glu + H2O
Met + Glu
show the reaction diagram
-
cleaved at about 10% of the maximal rate
-
-
?
Met-Gly + H2O
Met + Gly
show the reaction diagram
Met-Ile + H2O
Met + Ile
show the reaction diagram
Met-Leu + H2O
Met + Leu
show the reaction diagram
Met-Met + H2O
Met + Met
show the reaction diagram
-
-
-
ir
Met-Ser + H2O
Met + Ser
show the reaction diagram
Met-Thr + H2O
Met + Thr
show the reaction diagram
Met-Val + H2O
Met + Val
show the reaction diagram
norleucyl-Ala + H2O
norleucine + Ala
show the reaction diagram
-
-
-
ir
Ser-Ala + H2O
Ser + Ala
show the reaction diagram
Thr-Ala + H2O
Thr + Ala
show the reaction diagram