3.4.11.9: Xaa-Pro aminopeptidase
This is an abbreviated version!
For detailed information about Xaa-Pro aminopeptidase, go to the full flat file.
Reaction
release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide
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Synonyms
aminoacylproline aminopeptidase, aminopeptidase P, aminopeptidase P-like enzyme, aminopeptidase P1, aminopeptidase, aminoacylproline, AMPP, AP-P, APaseP, APP, APP1, APPro, DAP-P, dapUm, Dr-smAPP, Ec-smAPP, ecAPP, hAPP1, hcAMPP, Icp55, LeAPP1, LeAPP2, M24B peptidase, mAmP, Membrane-bound AmP, Membrane-bound APP, membrane-bound proline-specific APaseP, More, Mt-smAPP, Pa-PepP, PEPP, PepQ, peptidase PepQ, PepX aminopeptidase, PfAPP, proline aminopeptidase, sll0136, small aminopeptidase-P, TgAPP, TvMP50, X-Pro aminopeptidase, X-prolyl aminopeptidase, X-prolyl aminopeptidase 2, X-prolyl aminopeptidase 3, X-prolyl peptidase, X-prolyl-dipeptidyl aminopeptidase, Xaa-Pro aminopeptidase, Xaa-Pro aminopeptidase-1, Xaa-Pro aminopeptidase-2, Xaa-Pro dipeptidase, XPD, XpmA, XPNEP2, XPNPEP-1, XPNPEP-2, XPNPEP1, XPNPEP2, XPNPEP3, YpdF
ECTree
Source Tissue
Source Tissue on EC 3.4.11.9 - Xaa-Pro aminopeptidase
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adult fly
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upregulation of Xaa-Pro aminopeptidase-1, XPNPEP-1, in renal cell carcinoma from von Hippel-Lindau patients, and a strong decrease of XPNPEP-2, quantitative proteomic analysis, overview
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expression of GFP-fusion protein
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low activity in patients with angio-oedema
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adult fly, high level
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expression of GFP-fusion protein
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brush border membrane
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small inestinal epithelial cell
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microvillar membrane
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cortex
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brush border membrane
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microvillar membrane
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enriched in caveolae on the luminal surface of pulmonary vascular endothelium. Lung vascular targeting is assessed using a human/mouse chimeric monoclonal antibody (833c) against APP
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adult fly
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the enzyme colocalizes with collagens Col3 and Col4 in fetal ovaries around the germ cells, GCN, and along the ovigerous cords
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the enzyme colocalizes with collagens Col3 and Col4 in fetal ovaries around the germ cells, GCN, and along the ovigerous cords
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low activity
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adult fly
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additional information
developmentally regulated
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additional information
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developmentally regulated
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additional information
enzyme is expressed through the asexual erythrocytic cycle
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