Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

3.4.11.9: Xaa-Pro aminopeptidase

This is an abbreviated version!
For detailed information about Xaa-Pro aminopeptidase, go to the full flat file.

Word Map on EC 3.4.11.9

Reaction

release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide =

Synonyms

aminoacylproline aminopeptidase, aminopeptidase P, aminopeptidase P-like enzyme, aminopeptidase P1, aminopeptidase, aminoacylproline, AMPP, AP-P, APaseP, APP, APP1, APPro, DAP-P, dapUm, Dr-smAPP, Ec-smAPP, ecAPP, hAPP1, hcAMPP, Icp55, LeAPP1, LeAPP2, M24B peptidase, mAmP, Membrane-bound AmP, Membrane-bound APP, membrane-bound proline-specific APaseP, More, Mt-smAPP, Pa-PepP, PEPP, PepQ, peptidase PepQ, PepX aminopeptidase, PfAPP, proline aminopeptidase, sll0136, small aminopeptidase-P, TgAPP, TvMP50, X-Pro aminopeptidase, X-prolyl aminopeptidase, X-prolyl aminopeptidase 2, X-prolyl aminopeptidase 3, X-prolyl peptidase, X-prolyl-dipeptidyl aminopeptidase, Xaa-Pro aminopeptidase, Xaa-Pro aminopeptidase-1, Xaa-Pro aminopeptidase-2, Xaa-Pro dipeptidase, XPD, XpmA, XPNEP2, XPNPEP-1, XPNPEP-2, XPNPEP1, XPNPEP2, XPNPEP3, YpdF

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.11 Aminopeptidases
                3.4.11.9 Xaa-Pro aminopeptidase

KM Value

KM Value on EC 3.4.11.9 - Xaa-Pro aminopeptidase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
3
(4-nitro)Phe-Pro-HN-CH2-CH2-NH-o-aminobenzoyl
-
-
0.22
(4-nitro)Phe-Pro-Pro-HN-CH2-CH2-NH-o-aminobenzoyl
-
-
0.087 - 0.14
2-aminobenzoyl-L-Lys-L-Pro-L-Pro-4-nitroanilide
0.087 - 0.14
Abz-L-Lys-L-Pro-L-Pro-4-nitroanilide
0.15
Arg-homoPro-Pro-Ala-NH2
-
-
1.23
Arg-Pro
-
-
2.1 - 8.4
Arg-Pro-Ala
0.16 - 1.4
Arg-Pro-Pro
0.0007
Arg-Pro-Pro-benzylamide
-
-
0.048 - 0.34
Arg-Pro-Pro-Gly-Phe
0.032 - 0.15
Arg-Pro-Pro-Gly-Phe-Ser
0.051 - 0.25
Arg-Pro-Pro-Gly-Phe-Ser-Pro
0.039 - 0.15
Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe
0.076
Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg
-
-
0.021 - 6.7
bradykinin
0.056
des-Arg9-bradykinin
-
pH 7.4, 37°C
0.51 - 0.86
FPHFD
0.4697
Gly-Pro-4-nitroanilide
-
pH 8, 37°C
0.32 - 40.4
Gly-Pro-Hyp
13.82
Gly-Pro-Pro-p-nitroanilide
-
-
0.018
K(Dnp)PPGFSPK(Abz)NH2
-
-
0.02
K(Dnp)PPGK(Abz)NH2
-
-
0.019
K(Dnp)PPK(Abz)NH2
-
-
0.51 - 16.9
L-Ala-L-Pro-4-nitroanilide
0.77
L-Ala-L-Pro-L-Ala
wild-type, pH 8.1, 37°C
0.308 - 0.837
L-Arg-L-Pro-L-Pro
0.03
L-Arg-L-Pro-L-Pro-Gly
-
-
-
2.5
L-Ile-L-Pro-L-Pro
-
pH 7, temperature not specified in the publication
4.7
L-Leu-L-Pro-L-Pro
-
pH 7, temperature not specified in the publication
0.96
L-Met-L-Pro
pH 5.0, 80°C
1.33
L-Tyr-L-Pro-L-Phe-NH2
-
-
-
13.6
L-Val-L-Pro-L-Pro
-
pH 7, temperature not specified in the publication
0.9
Leu-Pro-Pro
-
-
0.038 - 0.1
Lys(epsilon-dinitrophenol)-Pro-Pro-NH-CH3-CH2-NH-2-aminobenzoyl
0.15 - 0.46
Met-Ala-Ala
6.3 - 11.9
Met-Pro
1.9 - 9
Met-Pro-Ala
0.00883
N6-(2-aminobenzoyl)-L-Lys-L-Pro-L-Pro-4-nitroanilide
recombinant enzyme, pH 7.5, 30°C
0.077
Substance P
pH 8.2, 37°C, recombinant wild-type enzyme
0.72
Tyr-Ala-Ala
pH 7.5, 40°C
1.8
Tyr-Pro-Ala
pH 7.5, 40°C
0.72
Tyr-Pro-Leu-Gly-NH2
-
-
1.2
Tyr-Pro-Phe
-
-
1.02 - 1.6
Tyr-Pro-Phe-Pro-Gly
0.6 - 1.4
Tyr-Pro-Phe-Pro-Gly-Pro-Ile
1.4 - 1.8
YPWTQ
additional information
additional information
-