3.4.11.7: glutamyl aminopeptidase

This is an abbreviated version!
For detailed information about glutamyl aminopeptidase, go to the full flat file.

Reaction

release of N-terminal glutamate (and to a lesser extent aspartate) from a peptide =

Synonyms

acid aminopeptidase, acidic alpha-aminopeptidase, Aminopeptidase, aminopeptidase A, aminopeptidase A ectopeptidase, aminopeptidase, aspartate, aminopeptidase-A, angiotensinase, angiotensinase A, antigen BP-1/6C3 of mouse B lymphocytes, AP A, APA, Asp-AP, aspartate aminopeptidase, aspartyl aminopeptidase, aspartyl-aminopeptidase, BP-1, BP-1/6C3 antigen, BP1/6C3, Ca2+-activated glutamate aminopeptidase, Differentiation antigen gp160, EAP, ENPEP, GAP, GluAP, glutamyl (aspartyl)-specific aminopeptidase A, glutamyl aminopeptidase, glutamyl aminopeptidase (Lactococcus), glutamyl peptidase, glutamyl-aminopeptidase, glutamyl-AP, hAPA, L-alpha-aspartyl(L-alpha-glutamyl)-peptide hydrolase, L-aspartate aminopeptidase, LAP-A, Lb-PepA, Lc-PepA, leucine aminopeptidase A, M18 aspartyl aminopeptidase, mAPA, membrane aminopeptidase II, membrane-bound aspartyl-AP, MHJ_0125, More, N-terminal acidic amino acid-specific aminopeptidase, PepA, tricorn interacting factor F3, tricorn protease-interacting factor F3, type II Zn2+ membrane-bound aminopeptidase

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.11 Aminopeptidases

                3.4.11.7 glutamyl aminopeptidase

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Results	in table
10	Activating Compound
1128	AA Sequence
23	Application
1	CAS Registry Number
34	Cloned(Commentary)
2	Crystallization (Commentary)
520	Disease/ Diagnostics
4	Expression
23	General Information
7	IC50 Value
315	Inhibitors
6	kcat/KM [mM/s]
144	Ki Value [mM]
94	KM Value [mM]
92	Localization
101	Metals/Ions
64	Molecular Weight [Da]
47	Natural Substrates/ Products (Substrates)
2	Organic Solvent Stability
198	Organism
3	Pathway
19	PDB ID
55	pH Optimum
11	pH Range
1	pH Stability
3	pI Value
10	Posttranslational Modification
43	Protein Variants
35	Purification (Commentary)
5	Reaction
31	Reaction Type
134	Reference
203	Source Tissue
86	Specific Activity [micromol/min/mg]
3	Storage Stability
253	Substrates and Products (Substrate)
36	Subunits
243	Synonyms
42	Temperature Optimum [°C]
7	Temperature Range [°C]
19	Temperature Stability [°C]
75	Turnover Number [1/s]

pH Range

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pH Range on EC 3.4.11.7 - glutamyl aminopeptidase

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pH RANGE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

4 - 8

Lactobacillus delbrueckii subsp. lactis

F0HXE4

activity range of CuCu-PepA, profile overview

753449

4.5 - 8

Lactobacillus delbrueckii subsp. lactis

F0HXE4

activity range of CoCo-PepA, NiNi-PepA, and ZnZn-PepA, profiles overview

753449

4.5 - 8.5

Sus scrofa

-

-

36021

5 - 10

Lactococcus lactis ssp. lactis

-

recombinant enzyme, activity range, profile overview

755117

5 - 8

2 entries

6 - 8

2 entries

6 - 9

Plasmodium falciparum

Q8I2J3

-

680832

7 - 9

Glycine max

-

more than 80% activity at 30°C

717392

additional information

Homo sapiens

-

pH-profile, recombinant enzyme

665723

5 - 8

Lactobacillus delbrueckii subsp. lactis

F0HXE4

recombinant enzyme, activity range, profile overview

755117

5 - 8

Lactobacillus delbrueckii subsp. lactis

F0HXE4

activity range of MnMn-PepA, profile overview

753449

6 - 8

Oryctolagus cuniculus

-

-

36020

6 - 8

Sus scrofa

-

-

36020