3.3.1.2: S-adenosyl-L-methionine hydrolase (L-homoserine-forming)

This is an abbreviated version!
For detailed information about S-adenosyl-L-methionine hydrolase (L-homoserine-forming), go to the full flat file.

Word Map on EC 3.3.1.2

Reaction

S-adenosyl-L-methionine
+
H2O
=
L-homoserine
+
S-methyl-5'-thioadenosine

Synonyms

S-adenosylmethionine cleaving enzyme, methylmethionine-sulfonium-salt hydrolase, adenosylmethionine lyase, hydrolase, adenosylmethionine, hydrolase, methylmethionine sulfonium salt, methyl-L-methionine sulfonium salt hydrolase, methylmethionine sulfonium salt hydrolase, S-adenosylmethionine hydrolase, AdoMet hydrolase, AdoMetase, SAMase, Adenosylmethionine hydrolase, MMSHase, methylmethionine sulfonium hydrolase, S-adenosyl-L-methionine hydrolase

ECTree

     3 Hydrolases
         3.3 Acting on ether bonds
             3.3.1 Thioether and trialkylsulfonium hydrolases
                3.3.1.2 S-adenosyl-L-methionine hydrolase (L-homoserine-forming)

Reference

Reference on EC 3.3.1.2 - S-adenosyl-L-methionine hydrolase (L-homoserine-forming)

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Mazelis, M.; Levin, B.; Mallinson, N.
Decomposition of methyl methionine sulfonium salts by a bacterial enzyme
Biochim. Biophys. Acta
105
106-114
1965
Corynebacterium sp.
Manually annotated by BRENDA team
Spoerel, N.; Herrlich, P.
Colivirus-T3-coded S-adenosylmethionine hydrolase
Eur. J. Biochem.
95
227-233
1979
Enterobacteria phage T3
Manually annotated by BRENDA team
Spoerel, N.; Herrlich, P.; Bickle, T.A.
A novel bacteriophage defence mechanism: the anti-restriction protein
Nature
278
30-34
1979
Enterobacteria phage T3
Manually annotated by BRENDA team
Hughes, J.A.; Brown, L.R.; Ferro, A.J.
Expression of the cloned coliphage T3 S-adenosylmethionine hydrolase gene inhibits DNA methylation and polyamine biosynthesis in Escherichia coli
J. Bacteriol.
169
3625-3632
1987
Enterobacteria phage T3
Manually annotated by BRENDA team
Hughes, J.A.; Brown, L.R.; Ferro, A.J.
Nucleotide sequence and analysis of the coliphage T3 S-adenosylmethionine hydrolase gene and its surrounding ribonuclease III processing sites
Nucleic Acids Res.
15
717-729
1987
Enterobacteria phage T3
Manually annotated by BRENDA team
Collier, G.B.; Mattson, T.L.; Connaughton, J.F.; Chirikjian, J.G.
A novel Tn10 tetracycline regulon system controlling expression of the bacteriophage T3 gene encoding S-adenosyl-L-methionine hydrolase
Gene
148
75-80
1994
Enterobacteria phage T3
Manually annotated by BRENDA team
Good, X.; Kellogg, J.A.; Wagoner, W.; Langhoff, D.; Matsumura, W.; Bestwick, R.K.
Reduced ethylene synthesis by transgenic tomatoes expressing S-adenosylmethionine hydrolase
Plant Mol. Biol.
26
781-790
1994
Enterobacteria phage T3
Manually annotated by BRENDA team
Kramer, M.G.; Kellogg, J.; Wagoner, W.; Matsumura, W.; Good, X.; Peters, S.; Clough, G.; Bestwick, R.K.
Reduced ethylene synthesis and ripening control in tomatoes expressing S-adenosylmethionine hydrolase
Biology and Biotechnology of the Plant Hormone Ethylene (A. K. Kanellis et al. (eds. ))
34
307-319
1997
Enterobacteria phage T3
-
Manually annotated by BRENDA team
Takigawa, S.; Ishii, G.
Accumulation and decomposition of S-methylmethionine in cabbage
Acta Hortic.
517
457-462
2000
Brassica sp.
-
Manually annotated by BRENDA team
Hughes, J.A.
In vivo hydrolysis of S-adenosyl-L-methionine in Escherichia coli increases export of 5-methylthioribose
Can. J. Microbiol.
52
599-602
2006
Enterobacteria phage T3
Manually annotated by BRENDA team
LaMonte, B.L.; Hughes, J.A.
In vivo hydrolysis of S-adenosylmethionine induces the met regulon of Escherichia coli
Microbiology
152
1451-1459
2006
Enterobacteria phage T3
Manually annotated by BRENDA team