3.2.1.86: 6-phospho-beta-glucosidase

This is an abbreviated version!
For detailed information about 6-phospho-beta-glucosidase, go to the full flat file.

Reaction

Synonyms

6-phospho-alpha-glucosidase, 6-phospho-beta-glucosidase, AscB protein, bgl-2, BglA, BglA-2, BglA3, bglD, BglT, CelD, Cellobiose-6-phosphate hydrolase, Gan1D, LacG1, LacG2, More, P-beta-glc, PalH, Pbgl25-217, phospho-alpha-glucosidase, phospho-beta-glucosidase, phospho-beta-glucosidase A, phosphocellobiase, SPD_0247, SPy1599

ECTree

     3 Hydrolases

         3.2 Glycosylases

             3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds

                3.2.1.86 6-phospho-beta-glucosidase

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Results	in table
4	Activating Compound
8988	AA Sequence
1	CAS Registry Number
13	Cloned(Commentary)
1	Cofactor
5	Crystallization (Commentary)
2	Expression
13	General Information
1	General Stability
22	Inhibitors
9	kcat/KM [mM/s]
1	Ki Value [mM]
67	KM Value [mM]
4	Localization
9	Metals/Ions
15	Molecular Weight [Da]
10	Natural Substrates/ Products (Substrates)
39	Organism
2	Pathway
48	PDB ID
13	pH Optimum
2	pH Range
1	pH Stability
1	pI Value
39	Protein Variants
15	Purification (Commentary)
2	Reaction
1	Reaction Type
39	Reference
5	Specific Activity [micromol/min/mg]
4	Storage Stability
101	Substrates and Products (Substrate)
13	Subunits
58	Synonyms
1	Systematic Name
9	Temperature Optimum [°C]
2	Temperature Range [°C]
3	Temperature Stability [°C]
24	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 3.2.1.86 - 6-phospho-beta-glucosidase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

4-nitrophenyl 6-phospho-beta-glucoside + H2O

4-nitrophenol + D-glucose 6-phosphate

Streptococcus pneumoniae

-

-

750733

-

-

?

6-phospho-beta-D-glucosyl-(1->4)-D-glucose + H2O

D-glucose + D-glucose 6-phosphate

2 entries

cellobiose 6-phosphate + H2O

beta-D-glucose + glucose 6-phosphate

Streptococcus pneumoniae

A0A0H2UP35

-

732101

-

-

?

cellobiose 6-phosphate + H2O

D-glucose 6-phosphate + D-glucose

3 entries

additional information

?

-

3 entries

6-phospho-beta-D-glucosyl-(1->4)-D-glucose + H2O

D-glucose + D-glucose 6-phosphate

Escherichia coli

Q46829

-

750963

-

-

?

6-phospho-beta-D-glucosyl-(1->4)-D-glucose + H2O

D-glucose + D-glucose 6-phosphate

Oenococcus oeni

-

-

751192

-

-

?

cellobiose 6-phosphate + H2O

D-glucose 6-phosphate + D-glucose

Klebsiella aerogenes

-

-

136923

-

136923

?

cellobiose 6-phosphate + H2O

D-glucose 6-phosphate + D-glucose

Klebsiella aerogenes

-

-

136925

-

136925

?

cellobiose 6-phosphate + H2O

D-glucose 6-phosphate + D-glucose

Thermotoga maritima

Q9X108

-

655795

-

-

?

additional information

?

-

Lactobacillus gasseri

-

expression of P-beta-glc induced by lactose is characteristic of Lactobacillus gasseri. Because this lactic acid bacterium is a major inhabitant of the human intestine, this enzyme is a key glycosidase involved in lactose utilization

681716

-

-

?

additional information

?

-

Mycoplasma mycoides

Q6MSD6

single nucleotide polymorphism in the bgl gene coding for the 6-phospho-beta-glucosidase is one possible cause of the difference in bacterial virulence among strains of Mycoplasma mycoides subsp. mycoides SC. Bgl does not act as a direct virulence factor, but strains possessing the Bgl isoform Val204 with low hydrolysing activity are more prone to survive in environments that contain high levels of beta-D-glucosides, thus contributing in some extent to mycoplasmaemia

678941

-

-

?

additional information

?

-

Streptococcus pneumoniae

-

no activity with 2-nitrophenyl beta-D-galactopyranoside, 4-methylumbelliferyl N-acetyl-alpha-D-glucosaminide, 4-methylumbelliferyl beta-D-glucopyranoside, 4-methylumbelliferyl alpha-D-glucopyranoside, 2-nitrophenyl alpha-D-galactopyranoside, 4-nitrophenyl alpha-D-glucoside 6-phosphate, 4-nitrophenyl alpha-D-mannoside 6-phosphate, and 4-nitrophenyl alpha-D-galactoside 6-phosphate

750733

-

-

?