3.2.1.49: alpha-N-acetylgalactosaminidase

This is an abbreviated version!
For detailed information about alpha-N-acetylgalactosaminidase, go to the full flat file.

Word Map on EC 3.2.1.49

3.2.1.49

n-acetylgalactosamine

sialidase

fabry

schindler

exoglycosidase

neuroaxonal

d3-binding

gcmaf

angiokeratoma

alpha-linked

beta-galnac

macrophage-activating

pomatia

corporis

diffusum

biflorus

mucin-type

medicine

alpha-n-acetylgalactosaminyltransferase

alpha-n-acetylgalactosamine

asialo

diagnostics

biotechnology

Reaction

alpha-D-GalNAc-(1->3)-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-ceramide

beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-ceramide

Synonyms

2-acetamido-2-deoxy-alpha-D-galactoside acetamidodeoxygalactohydrolase, 4-nitrophenyl-alpha-N-acetylgalactosaminidase, AglA, alpha-acetylgalactosaminidase, alpha-galactosidase B, alpha-GalNAc, alpha-GalNAc-ase, alpha-GalNAcase, alpha-GalNAcase I, alpha-GalNAcase II, alpha-N acetylgalactosaminidase, alpha-N-acetylgalactosaminidase blood group A2 degrading enzyme, alpha-N-galactosaminidase IV, alpha-NAGA, alpha-NAGAL, alpha-NaGalase, envelope glycoprotein gp160, exo-alpha-N-acetylgalactosaminidase, N-acetyl-alpha-D-galactosaminidase, N-acetyl-alpha-galactosaminidase, NagA, NaGalase

ECTree

3 Hydrolases

3.2 Glycosylases

3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds

3.2.1.49 alpha-N-acetylgalactosaminidase

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
2	Activating Compound
289	AA Sequence
9	Application
1	CAS Registry Number
14	Cloned(Commentary)
1	Cofactor
3	Crystallization (Commentary)
407	Disease/ Diagnostics
2	Expression
27	General Information
2	General Stability
53	Inhibitors
3	kcat/KM [mM/s]
49	KM Value [mM]
9	Localization
7	Metals/Ions
40	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
101	Organism
2	Pathway
28	PDB ID
57	pH Optimum
8	pH Range
14	pH Stability
8	pI Value
9	Posttranslational Modification
23	Protein Variants
31	Purification (Commentary)
6	Reaction
1	Reaction Type
98	Reference
46	Source Tissue
60	Specific Activity [micromol/min/mg]
18	Storage Stability
111	Substrates and Products (Substrate)
31	Subunits
38	Synonyms
1	Systematic Name
32	Temperature Optimum [°C]
2	Temperature Range [°C]
23	Temperature Stability [°C]
5	Turnover Number [1/s]

Purification

print visible entries

print all entries

Purification on EC 3.2.1.49 - alpha-N-acetylgalactosaminidase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to Purification (commentary) Search

15 entries

enzyme from salivary gland cells

Homo sapiens

655748

enzyme mutant from cell culture by dialysis, ammonium sulfate fractionation, hydrophobic interaction, cation exchange, and anion exchange chromatography

native enzyme

native enzyme from cell culture supernatant by three chromatographic steps to homogeneity, recombinant enzyme from Saccharomyces cerevisiae to homogeneity 105.9fold by hydrophobic interaction chromatography, ultrafiltration, cation exchange chromatography, gel filtration, and anion exchange chromatography

Aspergillus niger

G5D7B5

716839

native enzyme from placenta by 4-aminophenyl thio-beta-D-galactose-ceramide hexoside-resin affinity

Homo sapiens

707791

native isozymes alpha-GalNAcase I and alpha-GalNAcase II from liver

Architeuthis sp.

707632

native isozymes alpha-GalNAcase I and II are isolated from liver homogenate by ammonium sulfate fractionation and separated from each other by gel filtration. Then they are further individually purified by cation exchange chromatography and gel filtration, and additionally by hydroxylapatite chromatography for isozyme alpha-GalNAcase II. Isozyme alpha-GalNAcase I is purified 440fold, isozyme alpha-GalNAcase II 544fold

Asterina amurensis

707791

partially

2 entries

recombinant enzyme

Clostridium perfringens

657266

recombinant His6-tagged enzyme from Escherichia coli strain BL21(DE3) by nickel affinity chromatography

Elizabethkingia meningoseptica

recombinant protein