3.2.1.49: alpha-N-acetylgalactosaminidase

This is an abbreviated version!
For detailed information about alpha-N-acetylgalactosaminidase, go to the full flat file.

Word Map on EC 3.2.1.49

Reaction

alpha-D-GalNAc-(1->3)-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-ceramide
+
H2O
=
D-GalNAc
+
beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-ceramide

Synonyms

alpha-acetylgalactosaminidase, N-acetyl-alpha-D-galactosaminidase, N-acetyl-alpha-galactosaminidase, 4-nitrophenyl-alpha-N-acetylgalactosaminidase, 2-acetamido-2-deoxy-alpha-D-galactoside acetamidodeoxygalactohydrolase, exo-alpha-N-acetylgalactosaminidase, alpha-galactosidase B, AglA, alpha-NAGAL, alpha-GalNAc, alpha-NaGalase, alpha-N-galactosaminidase IV, NaGalase, alpha-N-acetylgalactosaminidase blood group A2 degrading enzyme, alpha-NAGA, envelope glycoprotein gp160, NagA, alpha-GalNAcase I, alpha-GalNAcase II, alpha-GalNAcase, alpha-GalNAc-ase, alpha-N acetylgalactosaminidase

ECTree

     3 Hydrolases
         3.2 Glycosylases
             3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
                3.2.1.49 alpha-N-acetylgalactosaminidase

Molecular Weight

Molecular Weight on EC 3.2.1.49 - alpha-N-acetylgalactosaminidase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
102000
-
gel filtration
115000
-
non-denaturating polyacrylamide gel electrophoresis
130000
35000
-
2 * 35000, monomers associate to dimers at pH 4.2, SDS-PAGE
40000
43000
430000
-
about, isozyme alpha-GalNAcase I, gel filtration
440000
-
gel filtration
46000
-
x * 46000, native enzyme, SDS-PAGE
47000
-
x * 47000, isozyme alpha-GalNAcase I, SDS-PAGE
48000
48500
49100
-
x * 49100, SDS-PAGE
50000
-
4 * 50000, SDS-PAGE
52000
-
2 * 52000, probably two subunits with identical molecular weight, SDS-PAGE
54000
55000
55600
57000
-
57000, SDS-PAGE
70000
719600
-
x * 719600, denatured recombinant enzyme, x * 724200, native recombinant enzyme, SDS-PAGE
72100
-
x * 72100 Da, SDS-PAGE
724200
-
x * 719600, denatured recombinant enzyme, x * 724200, native recombinant enzyme, SDS-PAGE
76000
80000
-
pH 4.2, gel filtration
84000
-
gel filtration