3.2.1.49: alpha-N-acetylgalactosaminidase

This is an abbreviated version!
For detailed information about alpha-N-acetylgalactosaminidase, go to the full flat file.

Word Map on EC 3.2.1.49

3.2.1.49

n-acetylgalactosamine

sialidase

fabry

schindler

exoglycosidase

neuroaxonal

d3-binding

gcmaf

angiokeratoma

alpha-linked

beta-galnac

macrophage-activating

pomatia

corporis

diffusum

biflorus

mucin-type

medicine

alpha-n-acetylgalactosaminyltransferase

alpha-n-acetylgalactosamine

asialo

diagnostics

biotechnology

Reaction

alpha-D-GalNAc-(1->3)-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-ceramide

beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-ceramide

Synonyms

2-acetamido-2-deoxy-alpha-D-galactoside acetamidodeoxygalactohydrolase, 4-nitrophenyl-alpha-N-acetylgalactosaminidase, AglA, alpha-acetylgalactosaminidase, alpha-galactosidase B, alpha-GalNAc, alpha-GalNAc-ase, alpha-GalNAcase, alpha-GalNAcase I, alpha-GalNAcase II, alpha-N acetylgalactosaminidase, alpha-N-acetylgalactosaminidase blood group A2 degrading enzyme, alpha-N-galactosaminidase IV, alpha-NAGA, alpha-NAGAL, alpha-NaGalase, envelope glycoprotein gp160, exo-alpha-N-acetylgalactosaminidase, N-acetyl-alpha-D-galactosaminidase, N-acetyl-alpha-galactosaminidase, NagA, NaGalase

ECTree

3 Hydrolases

3.2 Glycosylases

3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds

3.2.1.49 alpha-N-acetylgalactosaminidase

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Results	in table
2	Activating Compound
289	AA Sequence
9	Application
1	CAS Registry Number
14	Cloned(Commentary)
1	Cofactor
3	Crystallization (Commentary)
407	Disease/ Diagnostics
2	Expression
27	General Information
2	General Stability
53	Inhibitors
3	kcat/KM [mM/s]
49	KM Value [mM]
9	Localization
7	Metals/Ions
40	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
101	Organism
2	Pathway
28	PDB ID
57	pH Optimum
8	pH Range
14	pH Stability
8	pI Value
9	Posttranslational Modification
23	Protein Variants
31	Purification (Commentary)
6	Reaction
1	Reaction Type
98	Reference
46	Source Tissue
60	Specific Activity [micromol/min/mg]
18	Storage Stability
111	Substrates and Products (Substrate)
31	Subunits
38	Synonyms
1	Systematic Name
32	Temperature Optimum [°C]
2	Temperature Range [°C]
23	Temperature Stability [°C]
5	Turnover Number [1/s]

KM Value

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KM Value on EC 3.2.1.49 - alpha-N-acetylgalactosaminidase

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8.8

2-nitrophenyl alpha-D-fucopyranoside

Homo sapiens

171228

0.56 - 0.73

2-nitrophenyl-alpha-N-acetylgalactosaminide

3 entries

6.8

4-methylumbelliferyl-alpha-D-galactopyranoside

Homo sapiens

171227, 208660

0.7 - 0.89

4-nitrophenyl alpha-D-N-acetylgalactosaminide

2 entries

0.6 - 6.6

4-nitrophenyl alpha-N-acetylgalactosaminide

8 entries

2.15

4-nitrophenyl N-acetyl-D-galactosamine

2 entries

0.036 - 0.59

Forssman hapten

2 entries

1.04 - 3.97

GalNAc-alpha-1,3-GalNAc-beta-1,3-Gal-alpha-1,4-Gal-beta-1,4-Glc-beta-1,1-ceramide

3 entries

N-acetyl-alpha-D-galactosaminide

Homo sapiens

208672

1.3 - 2.4

o-nitrophenyl-alpha-N-acetylgalactosaminide

2 entries

1.58 - 1.62

o-nitrophenyl-N-acetyl-alpha-D-galactosaminide

2 entries

0.05

ovine submaxillary asialoglycoprotein

Katsuwonus pelamis

208649

1.27 - 4.83

p-nitrophenyl N-acetyl-alpha-D-galactosaminide

2 entries

14.7

p-nitrophenyl-2-deoxy-alpha-D-galactopyranoside

Homo sapiens

171228

0.38

p-nitrophenyl-alpha-N-acetyl-D-galactosaminide

Arenibacter latericius

pH 7.2, 36°C

654777

0.23 - 5.8

p-nitrophenyl-alpha-N-acetylgalactosaminide

5 entries

1.1 - 1.35

p-nitrophenyl-N-acetyl-alpha-D-galactosaminide

2 entries

phenyl-alpha-N-acetylglucosaminide

Bos taurus

208666

1.27 - 4.83

serum vitamin D3-binding protein

2 entries

additional information

7 entries