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3.2.1.38: beta-D-fucosidase

This is an abbreviated version!
For detailed information about beta-D-fucosidase, go to the full flat file.

Word Map on EC 3.2.1.38

Reaction

colanic acid
+
H2O
=
beta-D-fucopyranose
 +
6-O-AcGlcbeta(1-4)[6-O-pyruvylGalbeta(1-4)GlcAbeta(1-3)Galbeta(1-3)]Fucbeta(1-4)Fucbeta-R

Synonyms

1,4-beta-fucoside hydrolase, beta-D-fucosidase, beta-D-fucoside fucohydrolase, beta-D-galactosidase/beta-D-fucosidase, beta-D-gluco/fuco/galactosidase, beta-D-glucosidase/beta-D-fucosidase, beta-fucosidase, beta-fucosidase I, beta-fucosidase II, BglMKg, colanase, FucA, M8 mutant of glycoside hydrolase GK3214, MeBglD2, More, Pb280, PRGH1

ECTree

     3 Hydrolases
         3.2 Glycosylases
             3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
                3.2.1.38 beta-D-fucosidase

Inhibitors

Inhibitors on EC 3.2.1.38 - beta-D-fucosidase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1-amino-1-deoxy-D-glucose
-
-
1-butanol
-
inhibition above 50 mM
1-ethyl-3-(3-dimethylaminopropyl)carbodiimide
-
-
1-propanol
-
inhibition above 50 mM
2-amino-2-deoxy-D-glucose
-
non-competitive inhibition
4-O-alpha-D-glucopyranosyl-D-glucose
Ovis aries aries
-
effective inhibitor at 50 mM
4-O-beta-D-galactopyranosyl-D-glucose
4-O-beta-D-glucopyranosyl-D-glucose
acetone
-
inhibition at low concentrations
acetonitrile
-
inhibition at low concentrations
arsenate
-
-
Ba2+
-
strong inhibition at 25 mM
beta-D-fructofuranosyl-alpha-D-glucopyranoside
-
-
beta-D-fucose
beta-D-galactose
beta-D-glucose
Ca2+
Achatina balteata
-
slight inhibition at 50 mM, beta-D-fucosidase II not affected
Co2+
Achatina balteata
-
50% inhibition at 50 mM for beta-D-fucosidase I, 22% inhibition for beta-D-fucosidase II
colanic acid
-
substrate inhibition at high concentrations
conduritol B epoxide
-
loss of activity towards both substrates beta-D-glucoside and beta-D-fucoside, inactivation followed an all-or-none-type of modification, inactivation reduced in the presence of Tris
CuSO4
-
64% inhibition at 1 mM, alpha-L-arabinosidase activity less affected
D-fucono-1,4-lactone
-
50% inhibition at 0.057 mM
D-fucono-gamma-lactone
D-galactono-1,4-lactone
dicarbonic acid diethyl ester
-
-
ethanol
-
inhibition above 50 mM
F-
Achatina balteata
-
slight inhibition at 50 mM, beta-D-fucosidase II less affected
Fe3+
-
complete inhibition at 25 mM
glucono 1,5-lactone
glycerol
interferes with enzyme activity
iodoacetate
-
strong inhibition
KI
Achatina balteata
-
lactose protects against inactivation
La3+
-
strong inhibition at 25 mM
methanol
-
inhibition above 50 mM
Mn2+
Achatina balteata
-
slight inhibition at 50 mM, beta-D-fucosidase II less affected
N-Acetylimidazole
Achatina balteata
-
progressive inactivation
N-bromosuccinimide
-
-
N-ethylmaleimide
-
strong inhibition
Ni2+
Achatina balteata
-
47% inhibition at 50 mM for beta-D-.fucosidase I, 25% inhibition at 50 mM for beta-D-fucosidase II
p-chloromercuribenzoate
p-nitrophenyl-beta-D-fucoside
-
competitive inhibition of beta-D-glucosidase
p-nitrophenyl-beta-D-glucoside
-
competitive inhibition of beta-D-fucosidase
Tetranitromethane
Achatina balteata
-
lactose protects against inactivation
additional information
-