3.2.1.11: dextranase
This is an abbreviated version!
For detailed information about dextranase, go to the full flat file.
Word Map on EC 3.2.1.11
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3.2.1.11
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dextrans
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streptococcus
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dental
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glucans
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plaque
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penicillium
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caries
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leuconostoc
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sobrinus
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dextransucrase
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isomaltose
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water-insoluble
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cariogenic
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mesenteroides
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colon-specific
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lipomyces
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downei
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sanguis
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glucosyltransferases
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funiculosum
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salivarius
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mutanase
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synthesis
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medicine
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starkeyi
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isomaltotriose
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agriculture
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degradation
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nutrition
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drug development
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isomalto-oligosaccharides
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biotechnology
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food industry
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glucan-binding
- 3.2.1.11
- dextrans
- streptococcus
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dental
- glucans
- plaque
- penicillium
- caries
- leuconostoc
- sobrinus
- dextransucrase
- isomaltose
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water-insoluble
-
cariogenic
- mesenteroides
-
colon-specific
- lipomyces
- downei
- sanguis
-
glucosyltransferases
- funiculosum
- salivarius
- mutanase
- synthesis
- medicine
- starkeyi
- isomaltotriose
- agriculture
- degradation
- nutrition
- drug development
- isomalto-oligosaccharides
- biotechnology
- food industry
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glucan-binding
Reaction
Synonyms
1,6-alpha-D-glucan-6-glucanohydrolase, 6-alpha-D-glucan 6-glucanohydrolase, alpha-1,6-D-glucan 6-glucanohydrolase, alpha-1,6-D-glucan-6-glucanohydrolase, Alpha-1,6-glucan-6-glucanohydrolase, alpha-D-1,6-glucan-6-glucanohydrolase, alpha-dextranase, alpha-glucanase, AODex, Dex, Dex2, Dex410, Dex49A, DexA, dextran hydrolase, dextranase, dextranase DL 2, dextranase I, dextranase II, Dextranase Plus L, dextransucrase, DL 2, DXSR, endo-dextranase, endodextranase, extracellular dextranase, Fjoh_4430, LSD1, More, rDex, SmDex, Teth39_0264, TLDex, TPDex
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Inhibitors
Inhibitors on EC 3.2.1.11 - dextranase
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aflatoxin B1
inhibits dextranase activities of CYP3A4-expressing cultures, maximum inhibition of 22% at 2 microg/ml. Only negligibly inhibits strain INVSC1 expressing dextranase
aflatoxin G1
substantially less inhibitory towards dextranase activities of CYP3A4-expressing cultures than aflatoxin B1, showing a maximum inhibition of about 12% at 2 microg/ml, whereas strain INVSC1 expressing dextranase is only marginally inhibited
Na+
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85% inhibition of the free enzyme, 60% inhibition of the immobilized enzyme
T-2 toxin
100% inhibition at 10 microg/ml of dextranase activities of CYP3A4-expressing cultures and strain INVSC1
Ca2+
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5 mM, isoform D-I 71% residual activity, isoform D-II 83% residual activity
Cu2+
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93% inhibition of the free enzyme, 56.5% inhibition of the immobilized enzyme
Fe2+
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41.5% inhibition of the free enzyme, 18% inhibition of the immobilized enzyme
Fe2+
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5 mM, isoform D-I 47% residual activity, isoform D-II 38% residual activity
Hg2+
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complete inhibition of the free enzyme and the immobilized enzyme
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23% inhibition of the free enzyme, 6% inhibition of the immobilized enzyme
Mn2+
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5 mM, isoform D-I 67% residual activity, isoform D-II 63% residual activity
Pb2+
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5 mM, isoform D-I 23% residual activity, isoform D-II 10% residual activity
Zn2+
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21% inhibition of the free enzyme, 8% inhibition of the immobilized enzyme
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not inhibited by Mn2+, Co2+, Zn2+, Ni2+, PCMB and EDTA
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additional information
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teeth rinsing product reagents, including carboxybenzene, ethanol, sodium fluoride, and xylitol have no effects on enzyme activity
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additional information
Chaetomium erraticum
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for successful adsorption, enzyme to bentonite ratios greater than 0.4 (w/w) have to be used as lower ratios lead to 90% enzyme inactivation due to bentonite contact
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additional information
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Zn2+, Co2+, Ni2+, Fe3+ and EDTA show no obvious inhibition at 1 mM
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additional information
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not inhibited by dithiothreitol, 2-mercaptoethanol and EDTA
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additional information
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stable to Cu2+, Fe3+, Mg2+, Zn2+, EDTA and iodoacetamide
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additional information
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not inhibited by Mn2+, Co2+, Al3+, Mg2+ and EDTA
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additional information
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degree of enzyme inactivation declines with increasing ratio dextranase per dextranase adsorbate bentonite, at a ratio below 0.5: (w/w) only one half of the initial activity is retained
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additional information
no significant inhibition of dextranase activities of CYP3A4-expressing cultures and strain INVSC1 at concentrations of 2, 20, 200, and 2000 ng/ml by deoxynivalenol, fumonisin B1, and ochratoxin A
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additional information
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no significant inhibition of dextranase activities of CYP3A4-expressing cultures and strain INVSC1 at concentrations of 2, 20, 200, and 2000 ng/ml by deoxynivalenol, fumonisin B1, and ochratoxin A
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