3.1.6.6: choline-sulfatase

This is an abbreviated version!
For detailed information about choline-sulfatase, go to the full flat file.

Reaction

Synonyms

BetC, choline sulfatase, choline sulphatase, sulfatase, choline

ECTree

     3 Hydrolases

         3.1 Acting on ester bonds

             3.1.6 Sulfuric-ester hydrolases

                3.1.6.6 choline-sulfatase

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Results	in table
5	Activating Compound
4358	AA Sequence
1	CAS Registry Number
3	Cloned(Commentary)
1	Crystallization (Commentary)
4	Expression
2	General Information
38	Inhibitors
11	kcat/KM [mM/s]
2	Ki Value [mM]
15	KM Value [mM]
13	Metals/Ions
4	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
15	Organism
1	Pathway
24	PDB ID
4	pH Optimum
3	pH Stability
1	Posttranslational Modification
6	Protein Variants
2	Purification (Commentary)
3	Reaction
1	Reaction Type
15	Reference
1	Source Tissue
2	Specific Activity [micromol/min/mg]
37	Substrates and Products (Substrate)
1	Subunits
8	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
11	Turnover Number [1/s]

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Turnover Number on EC 3.1.6.6 - choline-sulfatase

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TURNOVER NUMBER [1/s]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.043

4-Methylumbelliferyl sulfate

Sinorhizobium meliloti

O69787

pH 7.5, 25°C

749790

0.004

4-nitrophenyl methylphosphate

Sinorhizobium meliloti

O69787

wild-type, pH 6.0, 25°C

751335

0.1

4-nitrophenyl methylphosphonate

Sinorhizobium meliloti

O69787

wild-type, pH 6.0, 25°C

751335

0.035 - 0.22

4-nitrophenyl sulfate

2 entries

0.011 - 2.4

choline O-sulfate

4 entries

0.27

Choline sulfate

Sinorhizobium meliloti

O69787

pH 7.5, 25°C

749790

0.027

phosphoryl choline

Sinorhizobium meliloti

O69787

wild-type, pH 7.6, 25°C

751335

0.035

4-nitrophenyl sulfate

Sinorhizobium meliloti

O69787

pH 7.5, 25°C

749790

0.22

4-nitrophenyl sulfate

Sinorhizobium meliloti

O69787

wild-type, pH 7.6, 25°C

751335

0.011

choline O-sulfate

Sinorhizobium meliloti

O69787

mutant C54S, pH 7.6, 25°C

751335

0.012

choline O-sulfate

Sinorhizobium meliloti

O69787

mutant E386L, pH 7.6, 25°C

751335

0.035

choline O-sulfate

Sinorhizobium meliloti

O69787

mutant H104A, pH 7.6, 25°C

751335

2.4

choline O-sulfate

Sinorhizobium meliloti

O69787

wild-type, pH 7.6, 25°C

751335