3.1.6.6: choline-sulfatase

This is an abbreviated version!
For detailed information about choline-sulfatase, go to the full flat file.

Word Map on EC 3.1.6.6

3.1.6.6

sulfur

meliloti

sinorhizobium

osmoprotectant

betaine

sulfatases

intergenic

permease

Reaction

Synonyms

BetC, choline sulfatase, choline sulphatase, sulfatase, choline

ECTree

3 Hydrolases

3.1 Acting on ester bonds

3.1.6 Sulfuric-ester hydrolases

3.1.6.6 choline-sulfatase

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Results	in table
5	Activating Compound
4358	AA Sequence
1	CAS Registry Number
3	Cloned(Commentary)
1	Crystallization (Commentary)
4	Expression
2	General Information
38	Inhibitors
11	kcat/KM [mM/s]
2	Ki Value [mM]
15	KM Value [mM]
13	Metals/Ions
4	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
15	Organism
1	Pathway
24	PDB ID
4	pH Optimum
3	pH Stability
1	Posttranslational Modification
6	Protein Variants
2	Purification (Commentary)
3	Reaction
1	Reaction Type
15	Reference
1	Source Tissue
2	Specific Activity [micromol/min/mg]
37	Substrates and Products (Substrate)
1	Subunits
8	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
11	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 3.1.6.6 - choline-sulfatase

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betaine

Pseudomonas aeruginosa

linear competitive inhibitor

135659

chloramphenicol

Pseudomonas sp.

synthesis of the enzyme is repressed

135663

choline

3 entries

choline chloride

2 entries

Choline sulfate

Sinorhizobium meliloti

substrate inhibition

CN-

cysteine

Dimethylamine

Pseudomonas aeruginosa

uncompetitive inhibitor

135659

dimethylaminoethanol

Pseudomonas aeruginosa

uncompetitive inhibitor

dithiothreitol

F-

mercaptoethanol

methionine

N-ethylmaleimide

NaCl

Sinorhizobium meliloti

slight inhibition at high concentrations

135665

p-chloromercuribenzoate

phosphate

phosphorylcholine

sulfate

sulfite

tetramethylamine

Pseudomonas aeruginosa

uncompetitive inhibitor

135659

trimethylamine

Pseudomonas aeruginosa

uncompetitive inhibitor

135659

additional information

Sinorhizobium meliloti

O69787

not inhibitory: ammonium sulfate up to 70 mM

749790