3.1.6.6: choline-sulfatase

This is an abbreviated version!
For detailed information about choline-sulfatase, go to the full flat file.

Word Map on EC 3.1.6.6

3.1.6.6

sulfur

meliloti

sinorhizobium

osmoprotectant

betaine

sulfatases

intergenic

permease

Reaction

Synonyms

BetC, choline sulfatase, choline sulphatase, sulfatase, choline

ECTree

3 Hydrolases

3.1 Acting on ester bonds

3.1.6 Sulfuric-ester hydrolases

3.1.6.6 choline-sulfatase

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Results	in table
5	Activating Compound
4358	AA Sequence
1	CAS Registry Number
3	Cloned(Commentary)
1	Crystallization (Commentary)
4	Expression
2	General Information
38	Inhibitors
11	kcat/KM [mM/s]
2	Ki Value [mM]
15	KM Value [mM]
13	Metals/Ions
4	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
15	Organism
1	Pathway
24	PDB ID
4	pH Optimum
3	pH Stability
1	Posttranslational Modification
6	Protein Variants
2	Purification (Commentary)
3	Reaction
1	Reaction Type
15	Reference
1	Source Tissue
2	Specific Activity [micromol/min/mg]
37	Substrates and Products (Substrate)
1	Subunits
8	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
11	Turnover Number [1/s]

Expression

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Expression on EC 3.1.6.6 - choline-sulfatase

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the putative transcriptional regulator BetR activates betC and betR transcription in the presence of choline sulfate, whilst in the absence of choline sulfate BetR represses its own transcription. BetR directly binds to betC-betR intergenic region in vitro, with higher affnity in the presence of choline sulfate as cofactor

2 entries

transcription of betC and betR is not induced in the presence of high concentration of NaCl

2 entries