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3.1.6.4: N-acetylgalactosamine-6-sulfatase

This is an abbreviated version!
For detailed information about N-acetylgalactosamine-6-sulfatase, go to the full flat file.

Word Map on EC 3.1.6.4

Reaction

D-GalNAc-6-sulfate
+
H2O
=
D-GalNAc
+
sulfate

Synonyms

6-sulfatase, acetylgalactosamine 6-sulfatase, AtsA2, chondroitin sulfatase, chondroitinase, chondroitinsulfatase, galactose-6-sulfatase, galactose-6-sulfate sulfatase, GalNAc6S sulfatase, GALNS, N-acetylgalactosamine 6-sulfatase, N-acetylgalactosamine 6-sulphate sulphatase, N-acetylgalactosamine-6-sulfatase, N-acetylgalactosamine-6-sulfate sulfatase, sulfatase, acetylgalactosamine 6-, sulfatase, chondroitin

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.6 Sulfuric-ester hydrolases
                3.1.6.4 N-acetylgalactosamine-6-sulfatase

pH Optimum

pH Optimum on EC 3.1.6.4 - N-acetylgalactosamine-6-sulfatase

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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
3.5 - 4
3.8 - 4
-
hydrolysis of N-acetylgalactosamine 6-sulfate or galactose 6-sulfate
4
-
recombinant enzyme
4.2
-
and a second optimum at pH 5.2, 0.1 M sodium acetate buffer
4.4
-
and a second optimum at pH 4.9, 0.02 M sodium acetate buffer
4.9
-
and a second optimum at pH 4.4, 0.02 M sodium acetate buffer
5.2
-
and a second optimum at pH 4.2, 0.1 M sodium acetate buffer
6.5
-
release of sulfate from galactose 6-sulfate and N-acetylgalactosamine 6-sulfate