3.1.6.4: N-acetylgalactosamine-6-sulfatase
This is an abbreviated version!
For detailed information about N-acetylgalactosamine-6-sulfatase, go to the full flat file.
Word Map on EC 3.1.6.4
-
3.1.6.4
-
mucopolysaccharidosis
-
lysosomal
-
morquio
-
keratan
-
glycosaminoglycans
-
dysplasia
-
chondroitin-6-sulfate
-
sulfatases
-
arylsulfatase
-
elosulfase
-
n-acetylgalactosamine-4-sulfatase
-
medicine
-
kyphoscoliosis
-
odontoid
-
sumf1
-
synthesis
-
sanfilippo
-
pectus
-
platyspondyly
-
carinatum
-
valgum
- 3.1.6.4
- mucopolysaccharidosis
- lysosomal
- morquio
- keratan
- glycosaminoglycans
- dysplasia
- chondroitin-6-sulfate
-
sulfatases
- arylsulfatase
-
elosulfase
- n-acetylgalactosamine-4-sulfatase
- medicine
-
kyphoscoliosis
-
odontoid
- sumf1
- synthesis
-
sanfilippo
-
pectus
-
platyspondyly
-
carinatum
-
valgum
Reaction
Synonyms
6-sulfatase, acetylgalactosamine 6-sulfatase, AtsA2, chondroitin sulfatase, chondroitinase, chondroitinsulfatase, galactose-6-sulfatase, galactose-6-sulfate sulfatase, GalNAc6S sulfatase, GALNS, N-acetylgalactosamine 6-sulfatase, N-acetylgalactosamine 6-sulphate sulphatase, N-acetylgalactosamine-6-sulfatase, N-acetylgalactosamine-6-sulfate sulfatase, sulfatase, acetylgalactosamine 6-, sulfatase, chondroitin
ECTree
Advanced search results
Natural Substrates Products
Natural Substrates Products on EC 3.1.6.4 - N-acetylgalactosamine-6-sulfatase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REACTION DIAGRAM
?
-
-
enzyme is involved in chondroitin sulfate breakdown
-
-
?
additional information
?
-
-
concerted action of exoglycosidases and EC 3.1.6.4 in degradation of polymeric chondroitin 4-sulfate, no contribution of the enzyme to the degradation of chondroitin
-
-
?
additional information
?
-
-
enzyme is involved in lysosomal degradation of the glycosaminoglycans keratan sulfate and chondroitin 6-sulfate
-
-
?
additional information
?
-
-
the enzyme catalyzes the first step of intralysosomal keratan sulfate catabolism. In Morquito A syndrome the N-acetylglucosamine 6-sulfate sulfatase deficiency causes the accumulation of keratan sulfate in tissue and results in generalized skeletal dysplasia in affected patients
-
-
?
additional information
?
-
-
enzyme deficiency causes mucopolysaccharidosis type IV, i.e. Morquio A syndrome, an autosomal recessive inborn error, due to accumulation of sulfated glycosaminoglycans in lysosomes, overview
-
-
?