3.1.4.45: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase

This is an abbreviated version!
For detailed information about N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, go to the full flat file.

Word Map on EC 3.1.4.45

Reaction

glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose
+
H2O
=
N-acetyl-D-glucosamine
+
glycoprotein phospho-D-mannose

Synonyms

alpha-N-acetylglucosaminylphosphodiesterase, phosphodiester glycosidase, lysosomal alpha-N-acetyl-glucosaminidase, alpha-N-acetyl-D-glucosamine-1-phosphodiester acetamidodeoxyglucohydrolase, phosphodiester alpha-GlcNAcase, N-acetylglucosamine-1-phosphodiester N-acetylglucosaminidase, alpha-N-acetylglucosaminyl phosphodiesterase, lysosomal alpha-N-acetylglucosaminidase, alpha-N-acetyl-D-glucosamine-1-phosphodiester N-acetylglucosaminidase, 2-acetamido-2-deoxy-alpha-D-glucose 1-phosphodiester acetamidodeoxyglucohydrolase, UCE, mannose 6-phosphate-uncovering enzyme, NAGLU, mannose 6-phosphate uncovering enzyme, GH89, GlcNAc-1-phosphodiester-N-acetylglucosaminidase, uncovering enzyme, BACOVA_00430, GlcNAc-1-phosphodiester alpha-N-acetylglucosaminidase

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.4 Phosphoric-diester hydrolases
                3.1.4.45 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase

Localization

Localization on EC 3.1.4.45 - N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
-
in tubulovesicular regions of the trans-Golgi network and in clathrin-coated trans Golgi network vesicles and buds, GFP-fusion protein expressed in HeLa cells, localization of mutants E502stop and Y488A/Q492A/E502stop like wild-type
-
Manually annotated by BRENDA team
-
recombinant UCE expressed in CHO-K1 cells and in Sf9 insect cells
-
Manually annotated by BRENDA team