3.1.3.48: protein-tyrosine-phosphatase

This is an abbreviated version!
For detailed information about protein-tyrosine-phosphatase, go to the full flat file.

Word Map on EC 3.1.3.48

3.1.3.48

pp2a

mapks

autoimmune

erk

cyclin

leukemia

endothelial

ras

signal-regulated

lysosomal

okadaic

t-cells

metastasis

checkpoint

sirna

obesity

myeloid

3-kinase

adaptor

arthritis

vanadate

stat3

tumorigenesis

prostate

mellitus

phosphatidylinositol

cyclin-dependent

c-jun

pkc

rheumatoid

tyrosine-phosphorylated

hyperphosphorylation

nonreceptor

chk1

cytochemical

autophosphorylation

receptor-like

genistein

irs-1

insulin-stimulated

phosphopeptide

tartrate-resistant

grb2

c-src

jak2

fyn

paxillin

substrate-1

myelomonocytic

polo-like

medicine

pharmacology

diagnostics

drug development

Reaction

Synonyms

70Z-SHP, acid phosphatase, acid phosphatase activity, acid phosphatase ortholog, acid tyrosine phosphatase, alpha-PTP-PEST, AUM, Bd1204, BDP, Bmptp-h, Brain-derived phosphatase, BVP, CAPTPase, CD148, CD148 antigen, CD45, CD45 antigen, CD45 protein tyrosine phosphatase, Cdc25 phosphatase, Cdc25-like protein, Cdc25A, Cdc25B, Cdc25B phosphatase, Cdc25C, CDK2-associated dual specificity phosphatase, Ch-1PTPase, chick retinal tyrosine phosphatase-2, cold-active protein tyrosine phosphatase, CPTP1, CQMa102 phosphatase, Cryp-2, CRYP-2/PTPRO, CRYP-2/receptor-type tyrosine-protein phosphatase O, cysteine-dependent protein tyrosine phosphatase, cyt-PTPepsilon, density-enhanced phosphatase-1, DEP-1, DEP-1 phosphatase, DLAR, dPTP61F, DSP, DSP18, dual specificity phosphatase, Dual specificity phosphatase Cdc25A, Dual specificity phosphatase Cdc25B, Dual specificity phosphatase Cdc25C, dual specificity protein phosphatase, dual specificity protein phosphatase 23, dual specificity protein phosphatase 3, Dual specificity protein phosphatase hVH1, Dual specificity protein phosphatase hVH2, Dual specificity protein phosphatase hVH3, Dual specificity protein phosphatase PYST1, Dual specificity protein phosphatase PYST2, Dual specificity protein phosphatase VHR, dual-specificity (Thr/Tyr) MAPK protein phosphatase, dual-specificity phosphatase, dual-specificity protein phosphatase, dual-specificity protein tyrosine phosphatase 18, Dual-specificity tyrosine phosphatase TS-DSP6, Dual-specificity tyrosine phosphatase YVH1, DUSP, ED-Eya2, EhPRL, EpsB, ES cell phosphatase, FAP-1, Fap1, FLP1, GLEPP-1, GLEPP1, HAP, HCP, HD-PTP, Hematopoietic cell protein-tyrosine phosphatase, Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP, hematopoietic protein tyrosine phosphatase, Hematopoietic protein-tyrosine phosphatase, hematopoietic tyrosine phosphatase, HEPTP, His domain protein tyrosine phosphatase, histidine acid phosphatase, histidine domain-protein tyrosine phosphatase, HPTP beta-like tyrosine phosphatase, HPTP eta, HPTPbeta, HPTPbeta-CD, hPTPE1, IA-2, IA-2A, IA-2beta, IAR, ICAAR, IF1, IF2, insulinoma associated protein tyrosine phosphatase 2, islet cell antigen-related PTP, Islet cell autoantigen related protein, KIM-containing PTP, KIM-PTP, kinase associated phosphatase, kinase interaction motif phosphatase, kinase interaction motif-containing protein tyrosine phosphatases, L-CA, LAR, Late protein H1, LCA, LCA-related phosphatase, LDP-3, leucocyte common antigen-related protein tyrosine phosphatase, Leukocyte antigen related, leukocyte common antigen-related, LmACR2, LMJF_16_0230, LmPRL-1, LMW PTPase, LMW-PTP, LMWPTP, low molecular mass dual specificity phosphatase 3, Low molecular weight cytosolic acid phosphatase, Low molecular weight phosphotyrosine protein phosphatase, low molecular weight protein tyrosine phosphatase, low molecular weight protein-tyrosine phosphatase A, low molecular weight protein-tyrosine-phosphatase, low molecular weight-PTP, low-molecular weight PTPase, low-molecular-weight protein tyrosine phosphatase, Lpt1, LRP, Lymphoid phosphatase, lymphoid-specific tyrosine phosphatase, LyP, M1851, MAP kinase phosphatase, MAP-kinase phosphatase CPG21, MAPK-specific tyrosine phosphatase, MEG, mitogen-activated protein kinase phosphatase, mitogen-activated protein kinase phosphatase-1, mitogen-activated protein kinase-specific tyrosine phosphatase, Mitosis initiation protein, Mitosis initiation protein MIH1, Mitotic inducer homolog, MKP, MKP-1, MKP-1 like protein tyrosine phosphatase, MKP-2, MKP-3, MKP-4, MKP-5, MKP-7, MKP-X, MKP1, MKP5-C, More, MPTP, MPTP-PEST, MPtpA, MPtpB, MSP, N3PTP, NC-PTPCOM1, Neural-specific protein-tyrosine phosphatase, non-receptor protein tyrosine phosphatase, ORF5, orphan protein tyrosine phosphatase, OST-PTP, osteoclastic protein-tyrosine phosphatase, P19-PTP, p52shc, p65 PTPepsilon, p66shc, p67 PTPepsilon, P80, PC12-PTP1, PCPTP1, PEST, PGN_1525, Pgp, Phogrin, Phosphacan, phosphatase of regenerating liver-3, phosphatase, phosphoprotein (phosphotyrosine), phosphatase, phosphotyrosine, phosphoprotein phosphatase (phosphotyrosine), phosphotyrosine histone phosphatase, phosphotyrosine phosphatase, Phosphotyrosine phosphatase 13, phosphotyrosine phosphatase 1B, phosphotyrosine protein phosphatase, phosphotyrosine-specific PP, phosphotyrosylprotein phosphatase, Pmp1p, PP2A, PPase, pphA, PPM, PPT-phosphatase, PRL, PRL-1, PRL-3, PRL-related protein tyrosine phosphatase, probable low molecular weight protein-tyrosine-phosphatase, protein of regenerating liver-related protein tyrosine phosphatase, Protein phosphatase 1B, protein phosphatase 2A, protein phosphotyrosine phosphatase, protein Tyr phosphatase, protein tyrosine phosphatase, protein tyrosine phosphatase 1B, protein tyrosine phosphatase A, protein tyrosine phosphatase alpha, protein tyrosine phosphatase B, protein tyrosine phosphatase beta, protein tyrosine phosphatase epsilon, protein tyrosine phosphatase eta, protein tyrosine phosphatase H1, protein tyrosine phosphatase N12, protein tyrosine phosphatase N3, protein tyrosine phosphatase ny, Protein tyrosine phosphatase receptor-type T, protein tyrosine phosphatase SHP-1, protein tyrosine phosphatase sigma, protein tyrosine phosphatase xi, protein tyrosine phosphatase, non-receptor type 1, protein tyrosine phosphatase, receptor-type, Z polypeptide 1, protein tyrosine phosphatase-1B, protein tyrosine phosphatase-2, protein tyrosine phosphatase-BL, protein tyrosine phosphatase-H2, Protein tyrosine phosphatase-NP, protein tyrosine phosphatase-PEST, Protein-protein-tyrosine phosphatase HA2, protein-tyrosine phosphatase, Protein-tyrosine phosphatase 1B, Protein-tyrosine phosphatase 1C, Protein-tyrosine phosphatase 1E, Protein-tyrosine phosphatase 2C, Protein-tyrosine phosphatase 2E, Protein-tyrosine phosphatase 3CH134, protein-tyrosine phosphatase alpha, Protein-tyrosine phosphatase CL100, Protein-tyrosine phosphatase D1, Protein-tyrosine phosphatase ERP, Protein-tyrosine phosphatase G1, Protein-tyrosine phosphatase H1, Protein-tyrosine phosphatase LC-PTP, Protein-tyrosine phosphatase MEG1, Protein-tyrosine phosphatase MEG2, Protein-tyrosine phosphatase P19, Protein-tyrosine phosphatase PCPTP1, Protein-tyrosine phosphatase pez, Protein-tyrosine phosphatase PTP-RL10, Protein-tyrosine phosphatase PTP36, Protein-tyrosine phosphatase PTPL1, Protein-tyrosine phosphatase striatum-enriched, Protein-tyrosine phosphatase SYP, Protein-tyrosine-phosphatase SL, Protein-tyrosine-phosphate phosphohydrolase, Prp1, PrpA, PTEN, PTEN phosphoprotein phosphatase, PTK, PTP, PTP 1B, PTP epsilon, PTP IA-2beta, PTP-1B, PTP-1C, PTP-1D, PTP-2C, PTP-BAS, PTP-BL, PTP-E1, PTP-eta, PTP-F, PTP-H1, PTP-H2, PTP-HA2, PTP-like phytase, PTP-MEG2, PTP-NP, PTP-oc, PTP-PEST, PTP-phosphatase, PTP-SH2beta, PTP-SL, PTP-U2, PTP1, PTP1B, PTP1C, PTP1D, PTP1e, PTP1N13, PTP1N21, PTP2C, PTP3, PTP36, PtpA, PTPalpha, PTPase, PTPase YVH1, PTPase-MEG1, PTPase-MEG2, PtpB, PTPB1, PTPBAS, PTPbeta, PTPBR7, PTPD1, PTPepsilon, PTPepsilonC, PTPepsilonM, PTPeta, PTPetaCD, PTPG1, PTPgamma, PTPH1, PTPL1, PTPLP, PTPMEG, PTPN1, PTPN11, PTPN12, PTPN13, PTPN14, PTPN2, PTPN20 variant 15, PTPN21, PTPN22, PTPN23, PTPN3, PTPN4, PTPN4/PTP-MEG1, PTPN5, PTPN6, PTPN7, PTPN9, PTPNE6, PTPP, PTPPase, PTPPBSgamma, PTPPBSgamma-37, PTPPBSgamma-42, PTPRA, PTPRB, PTPRC, PTPRD, PTPRdelta, PTPRE, PTPRF, PTPRG, PTPRH, PTPRJ, PTPRK, PTPRM, PTPRN, PTPRN2, PTPRO, PTPRO, truncated, PTPRO-FL, PTPRomega, PTPROt, PTPRQ, PTPRR, PTPRS, PTPRT, PTPRU, PTPRV, PTPRZ, PTPRZ1, PTPS31, PTPsigma, PTPxi/RPTPbeta, PY protein phosphatase, Pyp1p, Pyp2p, R-PTP-alpha, R-PTP-beta, R-PTP-delta, R-PTP-epsilon, R-PTP-eta, R-PTP-gamma, R-PTP-kappa, R-PTP-mu, R-PTP-zeta, R2B phosphatase, receptor protein tyrosine phosphatase, receptor protein tyrosine phosphatase isoform delta, receptor protein tyrosine phosphatase isoform omega, receptor protein tyrosine phosphatase rho, receptor protein tyrosine phosphatase T, receptor protein tyrosine phosphatase {kappa}, receptor PTPepsilon, Receptor-linked protein-tyrosine phosphatase 10D, Receptor-linked protein-tyrosine phosphatase 99A, receptor-type protein tyrosine phosphatase J, Receptor-type protein-tyrosine phosphatase-kappa, receptor-type tyrosine-protein phosphatase R, reductant-inhibited PTPase1, RIP1, RNA/RNP complex-intereracting phosphatase, ROL B protein, RPTP, RPTP-BK, RPTPalpha, RPTPdelta, RPTPepsilon, RPTPgamma, RPTPkappa, RPTPlambda, RPTPmu, RPTPrho, RPTPrho/PTPRT, RPTPsigma, RPTPzeta, Saci-PTP, Saci0545, SAP1, Scr homology 2-containing tyrosine phosphatase, selective striatal enriched protein phosphatase, SH-PTP1, SH-PTP2, SH-PTP3, SH2 domain-containing tyrosine phosphatase-1, SH2 domain-containing tyrosine phosphatase-2, SHP, SHP-1, SHP-2, SHP1, SHP2, Siw14, Slr0328, Small tyrosine phosphatase, Small, acidic phosphotyrosine protein phosphatase, SP-PTP, Spd1837, SPD_1837, specific protein-tyrosine phosphatase, SPH-1, SPH-2, SPy_0036, SPy_0039, Src homology 2 domain-containing phosphatase-1, Src homology region 2 domain-containing phosphatase 1, Src homology-2 domain containing protein tyrosine phosphatase-1, Src homology-2 domain containing protein tyrosine phosphatase-2, STEP, STEP33, STEP46, STEP61, Stp1, striatal enriched protein tyrosine phosphatase, striatal-enriched protein-tyrosine phosphatase, striatal-enriched PTP, String protein, SynPTP, Syp, T cell protein tyrosine phosphatase, T-cell protein tyrosine phosphatase, T-cell protein-tyrosine phosphatase, T-cell PTP, T-DSP11, T200, TC PTP, TC-PTPase �, TC48, TCPTP, TCPTP/TC45, TcPTP1, testis- and skeletal-muscle-specific DSP, testis- and skeletal-muscle-specific dual specificity protein phosphatase, Testis-and skeletal-muscle-specific DSP, Tk-PTP, TK0241, TMDP, TpbA, TypPT, tyrosine O-phosphate phosphatase, tyrosine phosphatase, tyrosine phosphatase alpha, Tyrosine phosphatase CBPTP, tyrosine phosphatase epsilon, tyrosine phosphatase IA-2, tyrosine phosphatase Src homology region 2 domain-containing phosphatase 1, tyrosine phosphatase-1B, tyrosine-protein phosphatase, tyrosine-protein phosphatase non-receptor type 22, tyrosine-protein phosphatase non-receptor type 5, tyrosine-specific MAPK phosphatase, tyrosylprotein phosphatase, vaccinia H1-related PTP, VE-PTP, VHR, VHZ, Wzb, YopH, YwlE, YwqE, [phosphotyrosine]protein phosphatase

ECTree

3 Hydrolases

3.1 Acting on ester bonds

3.1.3 Phosphoric-monoester hydrolases

3.1.3.48 protein-tyrosine-phosphatase

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Results	in table
49	Activating Compound
125386	AA Sequence
15	Application
2	CAS Registry Number
110	Cloned(Commentary)
50	Crystallization (Commentary)
34098	Disease/ Diagnostics
10	Expression
156	General Information
4	General Stability
420	IC50 Value
1171	Inhibitors
113	kcat/KM [mM/s]
212	Ki Value [mM]
276	KM Value [mM]
136	Localization
43	Metals/Ions
76	Molecular Weight [Da]
160	Natural Substrates/ Products (Substrates)
549	Organism
1281	PDB ID
83	pH Optimum
22	pH Range
4	pH Stability
4	pI Value
18	Posttranslational Modification
269	Protein Variants
86	Purification (Commentary)
29	Reaction
1	Reaction Type
380	Reference
1	Renatured (Commentary)
307	Source Tissue
38	Specific Activity [micromol/min/mg]
10	Storage Stability
721	Substrates and Products (Substrate)
69	Subunits
1232	Synonyms
1	Systematic Name
46	Temperature Optimum [°C]
6	Temperature Range [°C]
16	Temperature Stability [°C]
164	Turnover Number [1/s]

Synonyms

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Synonyms on EC 3.1.3.48 - protein-tyrosine-phosphatase

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70Z-SHP

acid phosphatase

2 entries

acid phosphatase activity

Setaria cervi

751789

acid phosphatase ortholog

Francisella tularensis

the enzyme share the conserved RHGXRXP motif characteristic of the histidine acid phosphatase family

677341

acid tyrosine phosphatase

Periplaneta americana

677839

alpha-PTP-PEST