3.1.3.42: [glycogen-synthase-D] phosphatase
This is an abbreviated version!
For detailed information about [glycogen-synthase-D] phosphatase, go to the full flat file.
Word Map on EC 3.1.3.42
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3.1.3.42
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phosphorylase
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glycogen-bound
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adrenalectomized
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glucagon-treated
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g-component
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glucose-6-p
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insulin-mediated
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protein-glycogen
- 3.1.3.42
- phosphorylase
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glycogen-bound
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adrenalectomized
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glucagon-treated
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g-component
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glucose-6-p
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insulin-mediated
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protein-glycogen
Reaction
Synonyms
glycogen glucosyltransferase phosphatase, glycogen synthase D phosphatase, glycogen synthase phosphatase, glycogen synthetase phosphatase, UDP-glycogen glucosyltransferase phosphatase, UDPglucose-glycogen glucosyltransferase phosphatase, uridine diphosphoglucose-glycogen glucosyltransferase phosphatase
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Substrates Products
Substrates Products on EC 3.1.3.42 - [glycogen-synthase-D] phosphatase
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REACTION DIAGRAM
glycogen phosphorylase + H2O
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rabbit muscle glycogen phosphorylase
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muscle phosphorylase kinase + H2O
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alpha-subunit of rabbit muscle phosphorylase kinase
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glycogen synthase D + H2O
glycogen synthase I + phosphate
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glycogen synthase D from liver, glycogen synthase D1, D2 and D3 from muscle
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glycogen synthase D + H2O
glycogen synthase I + phosphate
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inactive glycogen synthase D
active glycogen synthase I, i.e. EC 2.4.1.11
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additional information
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a low basal synthase phosphatase activity and a defect in its response to insulin explains, at least in part, reduced insulin stimulation of skeletal muscle glycogen synthase associated with insulin resistance
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additional information
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little activity towards phosphorylase a or phosphohistone
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additional information
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glycogen synthase phosphatase interacts with heat shock factor to activate CUP1 gene transcription
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