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3.1.3.42: [glycogen-synthase-D] phosphatase

This is an abbreviated version!
For detailed information about [glycogen-synthase-D] phosphatase, go to the full flat file.

Word Map on EC 3.1.3.42

Reaction

[glycogen-synthase D]
+
H2O
=
[glycogen-synthase I]
+
phosphate

Synonyms

glycogen glucosyltransferase phosphatase, glycogen synthase D phosphatase, glycogen synthase phosphatase, glycogen synthetase phosphatase, UDP-glycogen glucosyltransferase phosphatase, UDPglucose-glycogen glucosyltransferase phosphatase, uridine diphosphoglucose-glycogen glucosyltransferase phosphatase

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.3 Phosphoric-monoester hydrolases
                3.1.3.42 [glycogen-synthase-D] phosphatase

Activating Compound

Activating Compound on EC 3.1.3.42 - [glycogen-synthase-D] phosphatase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Ca2+
-
5 mM, 2.4fold activation
D-glucosamine 6-phosphate
-
2 mM, 30°C, pH 7.8, 3.2fold activation
D-glucose 1-phosphate
-
2 mM, 30°C, pH 7.8, 3.8fold activation
D-glucose 6-phosphate
-
4.9fold activation, without D-glucose 6-phosphate 38.8% remainimng activity and additionally without D-glucose 6-phosphate 23.1% remaining activity
galactose 6-phosphate
-
0.1 mM, stimulates activity
glucosamine 6-phosphate
-
0.1 mM, stimulates activity
glucose 6-phosphate
Mg2+
-
5 mM, 3.7fold activation, without Mg2+ 33% remaining activity and additionally without D-glucose 6-phosphate 23.1% remaining activity
Mn2+
-
5 mM, 4.4fold activation
additional information
-
no effects of 5 mM K+ and Na+, and 2 mM 6-P-gluconate, D-fructose 1,6-bisphosphate, alpha-glycerol phosphate, creatine phosphate, phosphate, and SO42-
-