3.1.3.22: mannitol-1-phosphatase

This is an abbreviated version!
For detailed information about mannitol-1-phosphatase, go to the full flat file.

Reaction

Synonyms

D-mannitol 1-phosphatase, HMPREF0010_00722, M1Pase, M1Pase2, M1Pse, mannitol 1-phosphatase, mannitol 1-phosphate phosphatase, mannitol dehydrogenase, mannitol-1-phosphatase, mannitol-1-phosphate dehydrogenases/phosphatase, mannitol-1-phosphate-specific phosphatase, Mt1Pase, MtlD

ECTree

     3 Hydrolases

         3.1 Acting on ester bonds

             3.1.3 Phosphoric-monoester hydrolases

                3.1.3.22 mannitol-1-phosphatase

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Results	in table
1	Activating Compound
143	AA Sequence
6	Application
1	CAS Registry Number
6	Cloned(Commentary)
2	Expression
6	General Information
1	General Stability
1	IC50 Value
24	Inhibitors
1	kcat/KM [mM/s]
5	KM Value [mM]
6	Localization
15	Metals/Ions
6	Molecular Weight [Da]
43	Natural Substrates/ Products (Substrates)
56	Organism
4	Pathway
6	pH Optimum
5	pH Range
1	pI Value
1	Posttranslational Modification
1	Protein Variants
7	Purification (Commentary)
1	Reaction
1	Reaction Type
54	Reference
6	Source Tissue
17	Specific Activity [micromol/min/mg]
90	Substrates and Products (Substrate)
7	Subunits
42	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 3.1.3.22 - mannitol-1-phosphatase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

37 entries

mannitol 1-phosphate + H2O

mannitol + phosphate

2 entries

additional information

?

-

4 entries

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Acinetobacter baylyi

Q6FBP5

-

729646

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Alternaria alternata

-

pathway for NADPH regeneration and NADH oxidation, regulatory function in carbohydrate metabolism

94717

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Alternaria alternata

-

the enzyme is involved in D-mannitol biosynthesis from fructose 6-phosphate via mannitol 1-phosphate in the mannitol cycle

666230

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Amylomyces rouxii

-

-

94718

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Apium graveolens

-

mannitol metabolism

94715

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Apium graveolens

-

the enzyme is involved in D-mannitol biosynthesis from mannose 6-phosphate via D-mannitol 1-phosphate

666230

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Aspergillus nidulans

-

mannitol metabolism

94714

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Aspergillus niger

-

-

94719

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Aspergillus niger

-

pathway for NADPH regeneration and NADH oxidation, regulatory function in carbohydrate metabolism

94717

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Aspergillus niger

-

the enzyme is involved in D-mannitol biosynthesis from fructose 6-phosphate via mannitol 1-phosphate in the mannitol cycle

666230

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Botrytis cinerea

-

pathway for NADPH regeneration and NADH oxidation, regulatory function in carbohydrate metabolism

94717

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Caloglossa continua

-

final step of mannitol biosynthesis

653107

-

653107

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Caloglossa continua

-

the enzyme is involved in D-mannitol biosynthesis, unusual for red algae, required for adjustment of osmotic pressure due to highly changing environmental conditions, mannitol pathway regulation, overview

666230

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Caloglossa leprieurii

-

the enzyme is involved in D-mannitol biosynthesis, unusual for red algae, required for adjustment of osmotic pressure due to highly changing environmental conditions, mannitol pathway regulation, overview

666230

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Ceratocystis multiannulata

-

pathway for NADPH regeneration and NADH oxidation, regulatory function in carbohydrate metabolism

94717

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Cladosporium cladosporioides

-

pathway for NADPH regeneration and NADH oxidation, regulatory function in carbohydrate metabolism

94717

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Cyberlindnera jadinii

-

pathway for NADPH regeneration and NADH oxidation, regulatory function in carbohydrate metabolism

94717

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Dictyota sp.

-

high activity

666230

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Dunaliella salina

-

the enzyme is involved in D-mannitol biosynthesis from fructose 6-phosphate via mannitol 1-phosphate in the mannitol cycle

666230

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Ectocarpus siliculosus

-

highly specific substrate

730126

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Ectocarpus siliculosus CCAP 1310/4

-

highly specific substrate

730126

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Eimeria tenella

-

-

663703

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Eimeria tenella

-

mannitol metabolism

94713, 94720

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Eisenia sp. (in: Phaeophyceae)

-

high activity

666230

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Fusarium graminearum

-

pathway for NADPH regeneration and NADH oxidation, regulatory function in carbohydrate metabolism

94717

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Laminaria digitata

-

-

81101

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Neurospora crassa

-

-

94719

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Neurospora crassa

-

pathway for NADPH regeneration and NADH oxidation, regulatory function in carbohydrate metabolism

94717

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Penicillium chrysogenum

-

-

94718

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Penicillus frequentans

-

pathway for NADPH regeneration and NADH oxidation, regulatory function in carbohydrate metabolism

94717

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Platymonas suecica

-

the enzyme is involved in D-mannitol biosynthesis, D-mannitol is the main product of photosynthesis and is accumulated at high level, mannitol pathway overview

666230

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Pyricularia oryzae

-

-

94719

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Pyricularia oryzae

-

pathway for NADPH regeneration and NADH oxidation, regulatory function in carbohydrate metabolism

94717

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Spatoglossum sp.

-

high activity

666230

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Talaromyces islandicus

-

pathway for NADPH regeneration and NADH oxidation, regulatory function in carbohydrate metabolism

94717

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Thermomyces lanuginosus

-

pathway for NADPH regeneration and NADH oxidation, regulatory function in carbohydrate metabolism

94717

-

-

?

D-mannitol 1-phosphate + H2O

D-mannitol + phosphate

Trichothecium roseum

-

pathway for NADPH regeneration and NADH oxidation, regulatory function in carbohydrate metabolism

94717

-

-

?

mannitol 1-phosphate + H2O

mannitol + phosphate

Acinetobacter baylyi

Q6FBP5

-

729646

-

-

?

mannitol 1-phosphate + H2O

mannitol + phosphate

Acinetobacter baylyi ATCC 33305

Q6FBP5

-

729646

-

-

?

additional information

?

-

Acinetobacter baylyi

-

MtlD is a bifunctional enzyme of mannitol biosynthesis that combines mannitol-1-phosphate dehydrogenase and phosphatase activities in a single polypeptide chain

729646

-

-

?

additional information

?

-

Acinetobacter baylyi

Q6FBP5

MtlD is a bifunctional enzyme of mannitol biosynthesis that combines mannitol-1-phosphate dehydrogenase and phosphatase activities in a single polypeptide chain

729646

-

-

?

additional information

?

-

Acinetobacter baylyi ATCC 33305

Q6FBP5

MtlD is a bifunctional enzyme of mannitol biosynthesis that combines mannitol-1-phosphate dehydrogenase and phosphatase activities in a single polypeptide chain

729646

-

-

?

additional information

?

-

Alternaria alternata

-

D-mannitol is secreted by the fungus

666230

-

-

?