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3.1.3.17: [phosphorylase] phosphatase

This is an abbreviated version!
For detailed information about [phosphorylase] phosphatase, go to the full flat file.

Word Map on EC 3.1.3.17

Reaction

[phosphorylase a]
+ 5 H2O = 2 [phosphorylase b] + 4 phosphate

Synonyms

glycogen phosphorylase phosphatase, phosphorylase a phosphatase, phosphorylase phosphatase, PP1, ppase-1, PR-enzyme, protein phosphatase 1, protein phosphatase C, protein phosphatase-1, type 1 protein phosphatase

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.3 Phosphoric-monoester hydrolases
                3.1.3.17 [phosphorylase] phosphatase

Inhibitors

Inhibitors on EC 3.1.3.17 - [phosphorylase] phosphatase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-hydroxyethyl disulfide
-
-
5,5'-dithiobis(2-nitrobenzoic acid)
-
-
D-Pantethine
-
-
Disulfides
-
irreversible inactivation
glucose 1-phosphate
-
inhibits by binding to one subunit of phosphorylase a
glycerophosphate
-
-
glycogen
-
partially inhibits by binding to one subunit of phosphorylase a
iodoacetamide
-
50 mM, 30% inhibition after 1 h at 30°C
iodoacetic acid
-
50 mM, 30% inhibition after 1 h at 30°C
microcystin-LR
-
-
Mn2+
-
3 mM, 64% inhibition
NaCl
-
0.1-0.3 M, 40-96% inhibition
okadaic acid
-
-
phosphorylase b
-
-
poly(L-lysine)
-
0.001 mM, strong
protein
synthetic peptide analog of ribosomal protein S6
-
0.2 mM S6229-239, 50% inhibition
-
UDP-glucose
-
-
ZnCl2
-
10 mM
additional information
-