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3.1.2.4: 3-hydroxyisobutyryl-CoA hydrolase

This is an abbreviated version!
For detailed information about 3-hydroxyisobutyryl-CoA hydrolase, go to the full flat file.

Word Map on EC 3.1.2.4

Reaction

3-hydroxy-2-methylpropanoyl-CoA
+
H2O
=
CoA
 +
3-hydroxy-2-methylpropanoate

Synonyms

3-hydroxy-isobutyryl CoA hydrolase, 3-hydroxyisobutyryl-CoA hydrolase, BCH, beta-hydroxyisobutyryl-CoA hydrolase, beta-hydroxyisobutyryl-coenzyme A hydrolase, CHY1, HIB CoA hydrolase, HIB-CoA hydrolase, HIBCH, HIBYL-CoA hydrolase, HICH, hydrolase, 3-hydroxyisobutyryl coenzyme A, More, NGR_b20860, Smb20752, VutE

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.2 Thioester hydrolases
                3.1.2.4 3-hydroxyisobutyryl-CoA hydrolase

Specific Activity

Specific Activity on EC 3.1.2.4 - 3-hydroxyisobutyryl-CoA hydrolase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.073
recombinant BCH in Escherichia coli strain BL21(DE3) crude extract
244
-
purified recombinant enzyme, substrate 3-hydroxypropionyl-CoA
430
-
purified recombinant enzyme, substrate (S)-3-hydroxy-2-methylpropanoyl-CoA
additional information
-
-