3.1.2.4: 3-hydroxyisobutyryl-CoA hydrolase

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For detailed information about 3-hydroxyisobutyryl-CoA hydrolase, go to the full flat file.

Reaction

Synonyms

3-hydroxy-isobutyryl CoA hydrolase, 3-hydroxyisobutyryl-CoA hydrolase, BCH, beta-hydroxyisobutyryl-CoA hydrolase, beta-hydroxyisobutyryl-coenzyme A hydrolase, CHY1, HIB CoA hydrolase, HIB-CoA hydrolase, HIBCH, HIBYL-CoA hydrolase, HICH, hydrolase, 3-hydroxyisobutyryl coenzyme A, More, NGR_b20860, Smb20752, VutE

ECTree

     3 Hydrolases

         3.1 Acting on ester bonds

             3.1.2 Thioester hydrolases

                3.1.2.4 3-hydroxyisobutyryl-CoA hydrolase

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Results	in table
2394	AA Sequence
1	CAS Registry Number
5	Cloned(Commentary)
161	Disease/ Diagnostics
16	General Information
17	Inhibitors
8	Ki Value [mM]
5	KM Value [mM]
4	Localization
1	Metals/Ions
7	Molecular Weight [Da]
17	Natural Substrates/ Products (Substrates)
22	Organism
12	Pathway
17	PDB ID
6	pH Optimum
3	pH Range
4	Protein Variants
5	Purification (Commentary)
2	Reaction
5	Reaction Type
20	Reference
23	Source Tissue
6	Specific Activity [micromol/min/mg]
41	Substrates and Products (Substrate)
6	Subunits
28	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
5	Turnover Number [1/s]

Purification

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Purification on EC 3.1.2.4 - 3-hydroxyisobutyryl-CoA hydrolase

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PURIFICATION (Commentary)

ORGANISM

UNIPROT

LITERATURE

-

Rattus norvegicus

-

94558

by Ni chromatography

Arabidopsis thaliana

Q9LKJ1

710261

from rat liver, 7200fold, to homogeneity

Rattus norvegicus

-

653127

native enzyme from mitochondrial membranes of HL-60 cells by two-step heparin affinity chromatography method using divalent cations, e.g. Mg2+, as eluents

Homo sapiens

-

665823

recombinant enzyme from Escherichia coli, removal of His-tag with thrombin

Homo sapiens

-

653127